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10 Cards in this Set
- Front
- Back
EPINEPHERINE
(NONSELECTIVE ADRENERGIC AGONISTS) |
Therapuetics:Anaphlaxis shock,asthma
Kinetics:IV, topical, Inhaled Dynamics: beta 1&2, Alpha 1&2 contraindications:severe cardiac disease, close angel glaucoma Precautions; HTN, Pregnancy, DM, elderly, children with asthma |
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Epinephrine adverse reactions?
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Blood glucose, arrhythmias & angina
HTN crisis, cerebral hemmorrage extravasation |
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PHENYLEPHRINE
(Alpha-1 ADRENERGENIC AGONIST) |
Therapeutics: Relief of nasal congestion, mydriasis (opthalmic),treat vascular failure in shock.
Kinetics: IV or topical Dynamics: Vasoconstriction (alpha 1 agonists) Contraindications: SEVERE HTN, VT, closed angle glaucoma Precautions: Hyperthyroid, Pregnancy, Cardio vasc disease, decrease volume, asthma (bronchoconstriction) |
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Phenylephrine Adverse reactions and interactions?
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HA, reflex bradycardia,
Restlessness and excitability(especially with concurrent MAOI use) Interactions: MAOI and tricyclic antidepressants |
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DOPAMINE
(BETA-ADRENERGIC AGONISTS) |
Therapeutics: Tx of hemodynamic imbalance in shock (low=renal perfusion, High= up B/P c vasoconstriction)
Kinetics: Rapid action,wide distribution(no bloodbrain barrier cross), take up into adrenergic nerve terminals. Dynamics: Alph/beta 1 directly, releases stored epinephrine indirectly. Contraindications: Pheocromocytoma, uncorrected tachy rythms and v-fib, correction of acidosis pre med. |
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Dopamine adverse reactions?
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Common: ectopic bts, tachycardia, dyspnea, and Hypotension
rare:abnormal conduction, bradycardia, wide qrs, piloerection O.D.: excessive hypertension |
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What to do for dopamine extravasation?
How to avoid? |
Give phentolamine SQ to area-causes vasodilation to flush dopamine into system.
Give meds via central line and make sure line flushes before giving drug. Monitor hemodynamic pressures. |
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PRAZOSIN
(ALPHA-ADRENERGIC ANTAGONISTS) |
Therapuetics: Refractory heart failure, Raynauds vasospasm, prostatic outflow obstruction, HTN.
Kinetics: PO Dynamics: selectively blocks Alpha-1 receptors. Contraindications: Hypersensitivity Precautions: angina, pregnancy, heart failure or renal failure. |
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Prazosin adverse reactions and interactions?
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adverse reactions: Lightheadedness, dizziness, HA, drowsiness. FIRST DOSE SYNCOPE (give 1/2 dose 1st time give drug).
Driving caution!! Drug Interactions: Additive effect with other antihypertensives, Erectile dysfunction drugs (work against each other). NSAIDS decrease effect of this drug. |
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PROPRANOLOL
(BETA-ANDRENERGIC ANTAGONISTS) |
Therapuetics: HTN, Angina, atrial tach, VT, migraines, irreg. rhythms, DIG intoxications, MI, pheochromocytoma, hypertropic aortic stenosis
also- situational anxiety, withdrawl Kinetics: PO or IV dynamics: nonselective beta blocker (BETA 1 heart and BETA 2 lungs) acts on receptors. Contraindications: cardiac disorders and airway diseases. Raynaud's and concomitant use of antidepressants. Precautions: |