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11 Cards in this Set

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  • Back
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Rb (13q)
Retinoblastoma, osteosarcoma
Rb gene product blocks
G1 --> S phase of the cell cycle
p53 (17p)
Most human cancers, Li-Fraumeni syndrome
p53 gene product blocks
G1 --> S phase of the cell cycle
BRCA1 (17q)
Breast and ovarian cancer
DNA repair protein
BRCA2 (13q)
Breast cancer
DNA repair protein
p16 (9p)
Melanoma
APC (5q)
Colorectal cancer (associated with FAP)
WT1 (11p)
Wilms' tumor
NF1 (17q)
Neurofibromatosis type 1
NF2 (22q)
Neurofibromatosis type 2
Type 2 = 22
DPC (18q)
Pancreatic cancer
DPC--Deleted in Pancreatic Cancer.
DCC (18q)
Colon cancer
DCC-Deleted in Colon Cancer.