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25 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Expression
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Bacterial infection that commonly infects lungs, but can also infect other organs
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b________ infection that commonly infects _____, but can also infect other ______
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Expression
infects other organs besides lungs. |
central nervous system (meningitis)
Urinary system - kidneys circulatory system lymphatic system skelatal system |
systems
(cir____tory) lym_____ system sk______ system |
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most common afffect of tuberculosis
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pulmonary (85%)
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History
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Ancient Disease
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Epidemiology
Worldwide stat |
33% have TB bacteria
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Epidemiology
US |
15 m
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Epidemiology
Mortality |
2 m worldwide
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don't be a tard muffin...starts with t ends with wo
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Epidemiology
Susceptibility |
immune system, nutrition, and medical acces are important
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cough nutrition cough
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Epidemiology
highest incidence in what demographics |
non-white males > 30 yrs and non-white females > 60 yrs; AIDS patients;
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affreekaaa
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Etiology
Causative agent |
Mycobacterium tuberculosis
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Etiology
Mycobacterium tuberculosis |
acid-fast rod-shaped bacterium
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____-fast rod-shaped b________
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Transmission
where most predominant? |
in countries and conditions where sanitation is lacking
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Transmission
specific |
Respiratory droplets carry the M. tuberculosis
highly infectious: only about 10 cells needed to infect |
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Pathogenesis
Step 1 |
Bacteria reach lungs, phagogcytized by macrophages; bacteria grow inside macrophages
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Bacteria reach _____, phagogc______ by macr______; bacteria grow inside macr_____
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Pathogenesis
Primary Tuberculosis |
initial infection; most remain latent (LTBI) with mild fever or no signs; ~5% develop active TB; after 3-4 weeks, immune system attacks infected macrophages forming tubercles – central core of bacteria in macrophage, surrounded by other cells; tubercles calcify
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initial ________; most remain _______(LTBI) with mild _____or no signs; ~5% develop ______ TB; after _-_ weeks, ______ system attacks infected macr_____ forming tubercles – central ___ of bacteria in macr______, surrounded by other cells; tu_______ calcify
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Pathogenesis
Secondary tuberculosis |
reactivation of infection weeks, months, or years after primary infection
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dont be a retard...what the fuck do you think secondary means?
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Pathogenesis
Causes chronic situation |
tubercles drain into bronchi; violent coughing with greenish or bloody sputum; fever, weight loss, anorexia, night sweats, extreme fatigue
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t______ drain into br__chi; violent coughing with greenish or blo____ sputum; fever, _____ loss, anorexia, night ______, extreme fat____
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Pathogenesis
Extrapulmonary tuberculosis |
infection of organs outside of lungs usually in immunocompromised patients
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tno ni hte ungls
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Prevention
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quarantine patients in negative pressure rooms
vaccine is used in some countries; more effective in children |
ive got a quarter for that tin of E + vaccine for TB
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Patients with ____ are not infectious
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LTBI
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ITBL
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Patients with active TB treated with
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streptomycin, isoniazid, rifampin, ethambutol usually in cocktail for 1 – 2 years; sometimes vaccine given with meds
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right it's harder to read than japanese. good luck.
r-f-m-i-, e-h-m-u-o-, s-r-e-t-o-y-i-, i-o-i-z-d |
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Recent increases in incidence/prevalence due to
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co-infection with HIV
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TB test (Mantoux test)
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injects PPD (purified protein derivatives) into forearm intradermally; after 48-72 hrs develop “induration”
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um no hint here bitch
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5 mm = + in category 1
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high risk groups
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10 mm = + in category 2
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high risk but not in category 1
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