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25 Cards in this Set

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  • Back
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Expression
Bacterial infection that commonly infects lungs, but can also infect other organs
b________ infection that commonly infects _____, but can also infect other ______
Expression
infects other organs besides lungs.
central nervous system (meningitis)
Urinary system - kidneys
circulatory system
lymphatic system
skelatal system
systems
(cir____tory)
lym_____ system
sk______ system
most common afffect of tuberculosis
pulmonary (85%)
History
Ancient Disease
Epidemiology
Worldwide stat
33% have TB bacteria
Epidemiology
US
15 m
Epidemiology
Mortality
2 m worldwide
don't be a tard muffin...starts with t ends with wo
Epidemiology
Susceptibility
immune system, nutrition, and medical acces are important
cough nutrition cough
Epidemiology
highest incidence in what demographics
non-white males > 30 yrs and non-white females > 60 yrs; AIDS patients;
affreekaaa
Etiology
Causative agent
Mycobacterium tuberculosis
Etiology
Mycobacterium tuberculosis
acid-fast rod-shaped bacterium
____-fast rod-shaped b________
Transmission
where most predominant?
in countries and conditions where sanitation is lacking
Transmission
specific
Respiratory droplets carry the M. tuberculosis
highly infectious: only about 10 cells needed to infect
Pathogenesis
Step 1
Bacteria reach lungs, phagogcytized by macrophages; bacteria grow inside macrophages
Bacteria reach _____, phagogc______ by macr______; bacteria grow inside macr_____
Pathogenesis
Primary Tuberculosis
initial infection; most remain latent (LTBI) with mild fever or no signs; ~5% develop active TB; after 3-4 weeks, immune system attacks infected macrophages forming tubercles – central core of bacteria in macrophage, surrounded by other cells; tubercles calcify
initial ________; most remain _______(LTBI) with mild _____or no signs; ~5% develop ______ TB; after _-_ weeks, ______ system attacks infected macr_____ forming tubercles – central ___ of bacteria in macr______, surrounded by other cells; tu_______ calcify
Pathogenesis
Secondary tuberculosis
reactivation of infection weeks, months, or years after primary infection
dont be a retard...what the fuck do you think secondary means?
Pathogenesis
Causes chronic situation
tubercles drain into bronchi; violent coughing with greenish or bloody sputum; fever, weight loss, anorexia, night sweats, extreme fatigue
t______ drain into br__chi; violent coughing with greenish or blo____ sputum; fever, _____ loss, anorexia, night ______, extreme fat____
Pathogenesis
Extrapulmonary tuberculosis
infection of organs outside of lungs usually in immunocompromised patients
tno ni hte ungls
Prevention
quarantine patients in negative pressure rooms
vaccine is used in some countries; more effective in children
ive got a quarter for that tin of E + vaccine for TB
Patients with ____ are not infectious
LTBI
ITBL
Patients with active TB treated with
streptomycin, isoniazid, rifampin, ethambutol usually in cocktail for 1 – 2 years; sometimes vaccine given with meds
right it's harder to read than japanese. good luck.
r-f-m-i-, e-h-m-u-o-, s-r-e-t-o-y-i-, i-o-i-z-d
Recent increases in incidence/prevalence due to
co-infection with HIV
TB test (Mantoux test)
injects PPD (purified protein derivatives) into forearm intradermally; after 48-72 hrs develop “induration”
um no hint here bitch
5 mm = + in category 1
high risk groups
10 mm = + in category 2
high risk but not in category 1