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15 Cards in this Set
- Front
- Back
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what antibiotic can increase level of statin & cause toxicity?
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Erythromycin, Ciprofloxacin (also azole antifungals); inhibits P-450 3A4 (Note - arythromycin does NOT do this)
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what is the statin of choice for patients on drugs that inhibit P450-3A4 enzymes?
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Pravastatin
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what does carbamazepine do to CYP 450?
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induces
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what does phenobarbital do to cyp 450?
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induces
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what does phenytoin do to cyp450?
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induces
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what does rifampin do to cyp 450?
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induces
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what does Griseofulvin do to cyp 450?
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induces
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what do psych drugs "tend" to do to cyp 450?
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induces
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what does cimetidine do to cyp 450? What is is it for?
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inhibits; H2 blocker used for GERD
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what does ciprofloxacicn do to cyp 450?
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inhibits
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what does erythromycin do to cyp 450?
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inhibits
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what do azole antifungals do to cyp 450?
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inhibit
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what does grape fruit juice do to cyp 450?
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inhibit
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what does Isoniazide do to cyp 450?
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inhibit
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what does ritonavir do to cyp 450? What is it?
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inhibit; it is a protease inhibitor
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