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5 Cards in this Set
- Front
- Back
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What are sulfonamides and trimethoprim?
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Sulfonamides and trimethoprim inhibit bacterial growth by preventing the synthesis of folic acid, folic acid is essential for the production of DNA, RNA and proteins
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What are some examples of sulfonamides or trimethoprim?
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-Trimethoprim-sulfamethoxazole (TMP-SMZ, Bactrim)
-Co-trimoxazole (Cotrim, Septra) |
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What are sulfonamides and trimethoprim used to treat?
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-UTI
-Chronic bronchitis -Otitis media |
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What are some possible adverse effects that may occur with sulfonamides or trimethoprim?
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-Hypersensitivity including Steven-Johnson syndrome
-Blood dyscrasias (hemolytic anemia, agranulocytosis, aplastic anemia) -Crystalluria (clients should consume 2-3 L/day to prevent crystals in the urine) -Jaundice -Photosensitvity -DO NOT administer if creatinine is less than 15 mL/min -Sulfonamides can increase the effects of warfarin (coumadin), monitor for increased bleeding, adjust dosage accordingly |
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Are sulfonamides and trimethoprim administered on an empty stomach?
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Yes, take with a full glass of water
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