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6 Cards in this Set

  • Front
  • Back
Follicular lymphoma.

A. What type of lymphoma is it? (Hodgkins, Non Hodgkins)
B. What is it's translocation?
t(2;8), t(8;14), t(8;22), t(11;14), t(14;18), t(3;14), t(9;22), t(15;17)
A. Non Hodgkin's lymphoma, low-grade B cell, occurs exclusively in adults, most common B - cell NHL.
B. t(14;18) BCL2 overexpression inhibits apoptosis
Mantle cell lymphoma.

A. What type of lymphoma is it? (Hodgkins, Non Hodgkins)
B. What is it's translocation?
t(2;8), t(8;14), t(8;22), t(11;14), t(14;18), t(3;14), t(9;22), t(15;17)
A. Non Hodgkin's lymphoma, low-grade B cell
B. t(11;14) juxtaposition of cyclin D1 gene to immunoglobulin heavy chain leads to increased Cyclin D1 expression
Burkitt lymphoma

A. What type of lymphoma is it? (Hodgkins, Non Hodgkins)
B. What is it's translocation?
t(2;8), t(8;14), t(8;22), t(11;14), t(14;18), t(3;14), t(9;22), t(15;17)
A. Non Hodgkin's lymphoma, intermediate grade B cell

B. t(2;8), t(8;14), t(8;22), though most common is the t(8;14) . always involves the cmyc gene translocation to the heavy chain locus
BCL2 overexpression inhibits apoptosis

which lymphoma?
t(14;18) BCL2 overexpression inhibits apoptosis;

Follicular lymphoma.Non Hodgkin's lymphoma, low-grade B cell,
juxtaposition of cyclin D1 gene to immunoglobulin heavy chain leads to increased Cyclin D1 expression


which lymphoma?
Mantle cell lymphoma. t(11;14) Non Hodgkin's lymphoma, low-grade B cell
always involves the cmyc gene translocation to the heavy chain locus

which lymphoma?
Burkitt t(2;8), t(8;14), t(8;22), though most common is the t(8;14)