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22 Cards in this Set

  • Front
  • Back
What is the ratio of ppl making anti-K if exposed to K antigen?
1 in 10
What are some examples of sulfhydryl reagents?
AET
2ME
DTT
What does sulfhydryl reagent do to K antigens?
Destroy
People with which phenotype are resisitant to some forms of Malaria?
Fy (a-b-)
Why are ppl with a certain Duffy phenotype resistant to Malaria?
because that Duffy ag is a receptor site for the merozoite
Ppl who are negative for Fya and Fyb are also negative to?
Fy3
Which antibodies show dosage?
Kidd, M, N, U, S, s
Which antibodies are very weak and difficult to detect, but are very important?
Kidd
Higher frequency.
Lua or Lub?
Lub
What are mixed field agglutination and in which group does it occur?
Agglutination with 2 population of cells

Lutheran
Lewis antigen are composed of? by?
water-soluable glycoproteins

tissue cells
Which antigens are not part of the red cell membrane and not present at birth?
Lewis
What is the most common Lewis phenotype?
Le(a-b+)
Comment on the development of Ii ags.
- i found on cord cells
- i will change to I in 2 years
What technique is used to stop anti-I reactions?
- prewarm plasma and red cells separately and test at 37oC
- use IAT
- wash cells by hand with warm saline
What happens when there is a reaction to Anti-I?
Cold hemagglutinin disease
higher frequency.
P1 or P2?
P1
Auto-anti-P causes what disease?
Paroxysmal cold hemablobinuria (autoimmune hemolytic anemia)
What is another name for Auto-Anti-P?
Donath-Landsteiner antibody
What is special about the reaction of auto-anti-P?
binds to P positive cells at low temp and causes hemolysis when cells are warmed to 37oC
MNS system, what are the main ags?
M, N, S, s, U
U antigen is inherited when ? and ? is inherited?
S and s