Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
30 Cards in this Set
- Front
- Back
|
Primary Bag Volume/Anticoag |
450 or 500 mL WB/63mL or 70 mL |
|
|
Preservative solutions (4) |
1. ACD 2. CPD (21 days) 3. CP2D (21 days) 4. CPDA-1 (35 Days) |
|
|
Purpose of Additive Solutions (2) |
1. Extend RBC survival and Function 2. Minimize RBC hemolysis (42 days) |
|
|
Limits for RBC storage life QC |
75% original Red Cell Mass found after 24 hours post-transfusion |
|
|
Rejuvenation Solutions (4) |
Pyruvate Inosine (washed off) Phosphate Adenine |
|
|
Rejuvination Limitations (3) |
1. Restore ATP and 2,3-BPG levels 2. For CPD/CPDA-1 RC units only 3. Only units <3 days after expiration |
|
|
Rejuvination does (3) |
1. Extend Exp. 10 years if glycerated+frozen 2. Extends exp. of AS-1 to 3 years 3. Extends thawed units by 24 hours |
|
|
WB storage Temps (2) |
1-6 C Ship 1-10 C |
|
|
All PRBC unit storage temps (2) |
1-6 C Ship 1-10 C |
|
|
Normal PRBC minimum QC |
<80% Hct w/o AS |
|
|
Leukoreduced PRBC QC (2) |
Retain 85% original RBC's WCC <5,000,000 per bag |
|
|
FFP storage requirements (2) |
<-18 C (1 year exp) <-65 C (7 year exp) |
|
|
FFP QC requirement |
In freezer within 8 hours of phlebotomy |
|
|
Random PLT storage requirements (1) |
20-24C with continuous agitation |
|
|
Random PLT expiration |
24 hrs (open system pooling 5 days (closed system collection) |
|
|
Random PLT QC requirements (3) |
No more than 24 hours without agitation 90% of units >5.5X10^10 plts Final pH >6.2 |
|
|
Indications for RBCs (3) |
Symptomatic Anemia Acute blood loss (hemodynamic compromise) Management of Hgb-opathies |
|
|
Contraindications for RBCs (3) |
Correctable Anemia Volume Expansion Increase oncotic pressure |
|
|
RBC Expected Benefits |
Hct/Hgb +3%/+1g/dL |
|
|
PLT Indications for use (3) |
Thrombocytopenia Dysfunctional PLT disorders Manage active PLT-related hemorrhage |
|
|
PLT contraindications (4) |
Bleeding unrelated to PLT PLT >100 Prophylactic for medication side-effects Cases of HIT, TTP, or ITP unless life-threatening |
|
|
PLT benefit (1) |
Increase count by 5 per unit or 30 per dose |
|
|
Unit Modification Effects (3) |
Leukoreduction: Reduce risk of CMV Irradiation: Reduce GVHD (t cells) Washed: Prevent Plasma protein effects |
|
|
Plasma Inidications (3) |
Replace coag factors Massive transfusion dilutional coagulopathy Bleeding, warfarin patients reverse effects |
|
|
Plasma Contraindications (3) |
Volume expansion DIC patients with fac 1 <100 mg/dL Coagulopathy corrected in concentrates |
|
|
Plasma Effects (1) |
In 70 kg adult: Factor levels +20-30% for every 2 units |
|
|
Cryo Storage requirements (2) |
AHF <-18C (1 year) Thawed 20-24 C 6/4 hours close/open |
|
|
Cryo Indications for use (2) |
Bleeding associated with factor 1/13 deff. 2nd line therapy for Hemophilia A and vWD |
|
|
Cryo Contraindications (1) |
Do not use if virus inactivated concentrates or preparations are available |
|
|
Cryo Benefits |
Dosage by weight and health, resolves bleeding issues. |
