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15 Cards in this Set
- Front
- Back
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Schistocytes indicate ____
while ____ indicate extravascular hemolysis. |
Schistocytes indicate INTRAVASCULAR HEMOLYSIS
while SPHEROCYTES indicate extravascular hemolysis. |
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What is the #1 cause of transfusion related death?
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TRALI
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What is the mortality rate of TRALI?
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5-25% (depending on the report)
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What products can cause post-transfusion purpura?
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RBC or Platelets
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What is the cause of post-transfusion purpura?
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Patient is PLA1 negative and get either RBC or Platelet transfusion with PLA1 which results in destruction of BOTH PLA1 positive and negative platelets.
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What is the treatment for post-transfusion purpura? Can you give platelets?
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IVIG, platelets are contraindicated
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If there is a SUSPICION of transfusion related death, when and how are you supposed to contact the FDA?
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1. Call the FDA w/in 24 hours of death
2. Full written report filed with FDA within 7 days of death |
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What is the risk of transfusion related transmission of disease?
HIV1 |
HIV1
1 in 2.3 million |
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What is the risk of transfusion related transmission of disease?
HBV |
HBV
1 in 220K |
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What is the risk of transfusion related transmission of disease?
HCV |
HCV
1 in 1.8 million |
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What is the risk of transfusion related transmission of disease?
HTLV1 |
1 in 2.993 million
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What is the risk of transfusion related transmission of disease?
HIV2, WNV, Syphilis, T. cruzi |
remote
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What is the risk of transfusion related transmission of disease?
Bacteria in platelets and RBC? |
Bacteria
Platelet: 1 in 75K RBC: 1 in 500K |
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How long do you defer a donor who has suspected or confirmed WNV?
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28 days from onset of SX or 14 days after resolution of SX, whichever is longer.
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How long do you defer a donor who tests positive for WNV but has no SX?
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120 days from date of positive test
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