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7 Cards in this Set
- Front
- Back
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What is Nicotine?
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an alkaloid from the dried leaves of nicotiniana tabacum plant
highly toxic and animals get by contaminated feed of ingestion of excessive amounts of tobacco leaves cigarettes or cigars |
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What is the mechanism of action for nicotine?
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-ganglionic and neuromuscular stimulalation (small dose)
-blockade at high doses -CNS stimulation followed by depression -respiratory failure -Stalks have teratogenic effect to sows -Nicotinana glauca is teratogenic to cows |
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What are the clinical signs of nicotine toxicosis?
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excitement
rapid respiration salivation vomiting diarrhea hypotension convulsions depresion respiratory failure |
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What are the lesions are associated with nicotine toxicosis?
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no lesions
may be signs of anoxia odor of nicotine in stomach contents (old cigar) |
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How so do you diagnose nicotine toxicosis?
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elevated nicotine in urine, blood, liver and kidney
history clinical signs |
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How do you treat nicotine toxicosis?
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-mecamylame as a ganglionic blockers only can have some benefits in early cases
-Atropinefor parasympathetic effects -Diazepam for seizures -Fluid therapy for hypertension -artificial respiration -removal of the source |
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What is the prognosis of nicotine toxicosis?
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poor with large doses
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