Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
16 Cards in this Set
- Front
- Back
What is xylitol used for?
|
Sugar substitute
|
|
What is the mode of action of xylitol toxicity in dogs?
|
Strong promoter of insulin release and can cause severe hypoglycemia
|
|
**When do signs of xylitol toxicity begin to appear in dogs?
|
As quickly as 30 minutes after ingestion- see sudden decrease in blood glucose
|
|
*What is usually the first sign of xylitol toxicity?
|
Vomiting
|
|
What is the main organ of xylitol metabolism?
|
Liver
|
|
What is the mechanism of liver necrosis from xylitol toxicity? What are the sequelae?
|
Unknown
Severe necrosis---> secondary impaired clotting factor production & DIC--> hemorrhage & often die |
|
When are elevated liver enzymes detected in some dogs with xylitol toxicity?
|
8-12 hours
|
|
Animals with hepatic injury from xylitol consumption usually become acutely ill in about ______ hours.
|
48
|
|
What is the treatment for xylitol toxicity?
|
No antidote!!!!!
|
|
What is 2,4-dichlorophenoxyacetic acid used for?
|
Common systemic pesticide/herbicide used in control of broadleaf weeds
|
|
**What is the most common source of 2,4-D poisoning?
|
Almost always due to accidental ingestion of concentrates or discarded excess or pooled sprays
|
|
**What are the primary clinical signs of 2,4-D toxicity?
|
Neurological
|
|
What are the best specimens for laboratory confirmation of 2,4-D toxicity?
|
Plasma or serum
|
|
What is the treatment of 2,4-D toxicity?
|
No specific antidotes
|
|
What is the prognosis of 2,4-D toxicity?
|
Unless severe CNS depression, recovery should be rapid
|
|
How are 2,4-D and canine lymphoma related?
|
Found that dogs in homes where lawns were treated with 2,4-D were twice as likely to develop malignant lymphoma
|