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16 Cards in this Set

  • Front
  • Back
What is xylitol used for?
Sugar substitute
What is the mode of action of xylitol toxicity in dogs?
Strong promoter of insulin release and can cause severe hypoglycemia
**When do signs of xylitol toxicity begin to appear in dogs?
As quickly as 30 minutes after ingestion- see sudden decrease in blood glucose
*What is usually the first sign of xylitol toxicity?
Vomiting
What is the main organ of xylitol metabolism?
Liver
What is the mechanism of liver necrosis from xylitol toxicity? What are the sequelae?
Unknown
Severe necrosis---> secondary impaired clotting factor production & DIC--> hemorrhage & often die
When are elevated liver enzymes detected in some dogs with xylitol toxicity?
8-12 hours
Animals with hepatic injury from xylitol consumption usually become acutely ill in about ______ hours.
48
What is the treatment for xylitol toxicity?
No antidote!!!!!
What is 2,4-dichlorophenoxyacetic acid used for?
Common systemic pesticide/herbicide used in control of broadleaf weeds
**What is the most common source of 2,4-D poisoning?
Almost always due to accidental ingestion of concentrates or discarded excess or pooled sprays
**What are the primary clinical signs of 2,4-D toxicity?
Neurological
What are the best specimens for laboratory confirmation of 2,4-D toxicity?
Plasma or serum
What is the treatment of 2,4-D toxicity?
No specific antidotes
What is the prognosis of 2,4-D toxicity?
Unless severe CNS depression, recovery should be rapid
How are 2,4-D and canine lymphoma related?
Found that dogs in homes where lawns were treated with 2,4-D were twice as likely to develop malignant lymphoma