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4 Cards in this Set
- Front
- Back
What are the uses of fluoride?
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highly toxic sodium fluoride and sodium fluorosilicate are no longer used as insectides in the US
soduim flualuminnnate (cryolite) which has a very low solubility and toxicity, is used as a plate insecticide hydrofluoric acid is an industral toxicant |
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What are the sources of fluoride?
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forages and pastures can be contamination from industry
natural waters feed and minerals supplements fluoride is a normal constituent of forages and plants that grow in fluoride - rich soil herbaceceous parts accumulate large amounts but not seeds |
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What is the toxicity of fluodide?
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acute fluoride toxicosis is not common
chronic fluoride toxicosis is mainly seen in herbivores especially dairy cattle toxic level for most large animals are 40-60ppm -factors influencing chronic fluoride toxicity |
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What are the mechanism of action of fluoride?
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acute toxicosis
-caustic effect on the GI mucosa -hypocalcemia -coagulation defect -increase capillary permeability -inhibition of many enzymes |