Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
10 Cards in this Set
- Front
- Back
|
what are the side effects of ipecac?
|
drowsiness which can mask poison's effect
can delay admin/reduce effectiveness of other treatments eg activated charcoal |
|
|
when is emesis indicated for decontamination?
|
not indicated
|
|
|
when is emesis/gastric lavage ineffective?
|
>1hr post ingestion
|
|
|
what is the mainstay of recommendations for gastric decontamination?
|
activated charcoal
|
|
|
how does activated charcoal work?
|
large surface area adsorbs many drugs & poisons
|
|
|
when is charcoal not useful in poisoning?
|
iron, lithium, K+ (no binding)
poor binding EtOH, cyanide nil use in corrosive mineral acids & alkali |
|
|
what is "gut dialysis"?
|
repeated doses of oral activated charcoal which may enhance systemic elimination of some drugs
|
|
|
what is the role of laxatives in poisoning?
|
admin of golytely etc (polyethylene glycol electrolyte solution) can enhance decontamination after ingestion of iron tabs, enteric coated meds, illicit drug filled packets & foreign bodies
|
|
|
once decontamination is done, what are options for further eliminating toxins?
|
dialysis (peritoneal or haemo)
urinary alkalisation (eg salicylates) |
|
|
for what drugs is dialysis useful in overdose? (9)
|
carbamazepine
ethylene glycol phenobarb metformin salicylate theophylline valproic acid lithium methanol |
