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28 Cards in this Set
- Front
- Back
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most important exposure site
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skin
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parent compound as toxicant
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EtOH
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metabolite as toxicant
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methanol to formic acid
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free radical as toxicant
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paraquat and doxorubicin to superoxide
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doxorubicin
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chemotherapeutic agent that has cardiotoxicity
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methanol
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metabolized to formic acid which causes blindness
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ethylene glycol
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metabolized to calcium oxalate which causes renal failure
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methanol and ethylene glycol antidotes
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ethanol or fomepizole (4-methylpyrazole which inhibits alcohol dehydrogenase)
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these types of mercury enter CNS
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organic and elemental
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this type of mercury remains in peripheral tissues
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inorganic mercury; causes renal damage
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Lead toxicity
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anemia and basophilic stippling
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can cause wrist-drop and encephalopathy
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lead poisoning
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mercury poisoning can cause
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renal damage
gingivostomatitis CNS effects: visual disturbance, muscle tremor, and mental deterioration |
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vomiting with streaks of blood, increased HR, low BP, radiopaque stomach, and rectal exam positive for heme
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Fe intoxication
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heavy metal antagonists
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EDTA
dimercaprol succimer deferoxamine penicilamine |
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EDTA SEs
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Zn deficiency and renal damage
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dimercaprol administration and SEs
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IM in peanut oil
HTN and tachy |
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Succimer
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water-soluble analog of dimercaprol
orally effective and fewer SEs |
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deferoxamine
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given IV or IM to treat Fe intoxication
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penicilamine
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treat copper poisoning and wilson's disease
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prussian blue
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used to treat exposure to radioactive Cs, thallium, and a dirty bomb
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antidote for CO poisoning
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100% O2
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deferoxamine
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given IV or IM to treat Fe intoxication
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penicilamine
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treat copper poisoning and wilson's disease
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prussian blue
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used to treat exposure to radioactive Cs, thallium, and a dirty bomb
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antidote for CO poisoning
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100% O2
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this drug may cause cyanide intoxication
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nitroprusside
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cyanide detox
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sodium nitrite to methemoglobin
sodium thiosulfate to thiocyante hydroxocobalamin to cyanocobalamin |
