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33 Cards in this Set

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Naloxone use

reverse respiratory and cns depression due to opiod drugs.


Not necessary if intubated

Flumenazil use/

antagonist for benzodiazepine




not use if pt convoluse or history of tricyclic antidepressant overdose

acetaminophen

liver damage: measure aminotransferase and prothrombin




treat with acetylcysteine acts as a glutathionine substitute and bind toxic metabolist




acetadote is iv and mucomyst =orally

amphetamine and stimulants list
metha, cocain ectasy sudaphe street drugs like bath salts fat burners
treatment amphetamines

hyperthermia: lead to brain damage, hypotension, coagulopathy, renal failure


spray, fan tanke of clot... very high temps us neuromuscular paralysis


seizures: use iv benzodiazepines such as loreazepam

Anticholinergic drugs and classic symptom

red beet/flushed skin, hot dry mucus membranes, blurred vision,confusion delirium




drugs: antihistamines, tryclic antidepressants

anticholinergic treatment

Physostigmine... should be given slowly as not to cause bradycardia




and should not be given with tyrcics as can cause cardiotoxicity

tricyclic antidepressant overdose

symptoms :anticholinergic: tachycardia, dilated pupils, dry mouth, can cause wide qrs and depressed cardiac contractitliy< give sodium bicarbonate>


three cs:cardiotoxicity,convusion, coma


norepi for hypotension


comatreatme endotracheal intbation

aspirin salicylate symptoms

respiratory alkalosis due to medullary stimulation,


hyperthermia: uncoupling of oxidative phosphor


decontamainate : gastic lavage


severe: hemodialysis

anticholinerestase intoxication: organophosphate, carbamates
atropine: give till stop wheezing
cardiotoxic depressant drugs: tricycics, quinidine,
Bicarbonate: Sodium
Iron salts
deferoxamine
fluoride, calcium channel blockers
calcium
digoxin and cardiac glycosides
digoxin antibodies
Theophyyline, caffeine, metraproterenol
esmolol
methanol, ethylene glycol
ethanol

flumenazil
benzodiazepine
fomepizole antidote
methanol, ethylene glycol
beta blocker
glucagon may reverse hypotension and bradycardia
cyanide
hydroxocobalmin converts cyanide to cyanocobalamin, vitamin b twleve
carbon monoxide
oxygen
anticholinergic agents delirium
physostigimine < may cause brady cardia seiqure and bronchil secretetions do not use with tricylcics
Organophosphate cholinesterase inhibitors
Pralidoxime
betal blockers

bradycardia and hypotension also can block sodium channels and create wide qrs


treat: b agonist atropine, glucagon craisce camp improve heart rate

Calcium channel blockers

slow av node, reduce cardiac output and blood pressure exp is nifedipine and dihydropyridines


treatment: whole bowel irrigation charcoal deal with hypotension add glucag and high dose insulin

cholinesterase inhibitors

exp are organophosphate and carbamate. Poisoning pests


stimulates muscarinic receptors: abdominal cramps, diarrhea, excessive salivation, sweating urinary frequency


dumbels pneumonic


Treatment: atropine and prlidosime< active at both musc and nicotinic while atropine inhib muscarininc

dumbels
diarrhea ,urination, miosis, muscle weakness, bronchospasm, excitation, lacrimation, seizures
cyanide

binds to cytochrome oxidase inhibiting oxygen utilization within cell and leading to cellular hypoxia and lactic acidosis. shortness breath agitation, tachycardia seizures coma hypotension death


treatment: cyanocobalmin, thiosulfate,nitrite

Digoxin

acute: hyperkalemia vomiting


longterm: hypokalemia heart block problems




treatment: digoxin antibodies and atropine for av heart block

ethanol and sedative hypnotic

hypothermia: environment and depressed shivering


benzodiapine treat: flumenazil

ethylene glycol methanol

can lead to metabolic acidosis, coma and blindness <formic acid> formic acid is formed from methanol


treatment: use inhibitor of alcohol dehydrogenous such as fomepizole... also can use ethanol

rattle snake venom

fasciculation, nausea, vomiting, tingling and metallic taste systematic coagulopathy




antivenin

theophylline

theophylline used for asthma and bronchospasm.


symptoms tachy cardia hypokalemia hyperglycemia< thing btwo activation>


treat with betal blocker <propanolo, esmolo


phenobarbital for convulsions