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33 Cards in this Set
- Front
- Back
Naloxone use
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reverse respiratory and cns depression due to opiod drugs. Not necessary if intubated |
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Flumenazil use/
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antagonist for benzodiazepine not use if pt convoluse or history of tricyclic antidepressant overdose |
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acetaminophen
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liver damage: measure aminotransferase and prothrombin treat with acetylcysteine acts as a glutathionine substitute and bind toxic metabolist acetadote is iv and mucomyst =orally |
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amphetamine and stimulants list
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metha, cocain ectasy sudaphe street drugs like bath salts fat burners
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treatment amphetamines
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hyperthermia: lead to brain damage, hypotension, coagulopathy, renal failure spray, fan tanke of clot... very high temps us neuromuscular paralysis seizures: use iv benzodiazepines such as loreazepam |
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Anticholinergic drugs and classic symptom
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red beet/flushed skin, hot dry mucus membranes, blurred vision,confusion delirium drugs: antihistamines, tryclic antidepressants |
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anticholinergic treatment
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Physostigmine... should be given slowly as not to cause bradycardia and should not be given with tyrcics as can cause cardiotoxicity |
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tricyclic antidepressant overdose
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symptoms :anticholinergic: tachycardia, dilated pupils, dry mouth, can cause wide qrs and depressed cardiac contractitliy< give sodium bicarbonate> three cs:cardiotoxicity,convusion, coma norepi for hypotension comatreatme endotracheal intbation |
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aspirin salicylate symptoms
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respiratory alkalosis due to medullary stimulation, hyperthermia: uncoupling of oxidative phosphor decontamainate : gastic lavage severe: hemodialysis |
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anticholinerestase intoxication: organophosphate, carbamates
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atropine: give till stop wheezing
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cardiotoxic depressant drugs: tricycics, quinidine,
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Bicarbonate: Sodium
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Iron salts
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deferoxamine
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fluoride, calcium channel blockers
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calcium
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digoxin and cardiac glycosides
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digoxin antibodies
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Theophyyline, caffeine, metraproterenol
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esmolol
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methanol, ethylene glycol
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ethanol
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flumenazil
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benzodiazepine
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fomepizole antidote
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methanol, ethylene glycol
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beta blocker
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glucagon may reverse hypotension and bradycardia
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cyanide
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hydroxocobalmin converts cyanide to cyanocobalamin, vitamin b twleve
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carbon monoxide
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oxygen
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anticholinergic agents delirium
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physostigimine < may cause brady cardia seiqure and bronchil secretetions do not use with tricylcics
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Organophosphate cholinesterase inhibitors
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Pralidoxime
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betal blockers
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bradycardia and hypotension also can block sodium channels and create wide qrs treat: b agonist atropine, glucagon craisce camp improve heart rate |
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Calcium channel blockers
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slow av node, reduce cardiac output and blood pressure exp is nifedipine and dihydropyridines treatment: whole bowel irrigation charcoal deal with hypotension add glucag and high dose insulin |
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cholinesterase inhibitors
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exp are organophosphate and carbamate. Poisoning pests stimulates muscarinic receptors: abdominal cramps, diarrhea, excessive salivation, sweating urinary frequency dumbels pneumonic Treatment: atropine and prlidosime< active at both musc and nicotinic while atropine inhib muscarininc |
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dumbels
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diarrhea ,urination, miosis, muscle weakness, bronchospasm, excitation, lacrimation, seizures
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cyanide
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binds to cytochrome oxidase inhibiting oxygen utilization within cell and leading to cellular hypoxia and lactic acidosis. shortness breath agitation, tachycardia seizures coma hypotension death treatment: cyanocobalmin, thiosulfate,nitrite |
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Digoxin
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acute: hyperkalemia vomiting longterm: hypokalemia heart block problems treatment: digoxin antibodies and atropine for av heart block |
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ethanol and sedative hypnotic
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hypothermia: environment and depressed shivering benzodiapine treat: flumenazil |
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ethylene glycol methanol
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can lead to metabolic acidosis, coma and blindness <formic acid> formic acid is formed from methanol treatment: use inhibitor of alcohol dehydrogenous such as fomepizole... also can use ethanol |
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rattle snake venom
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fasciculation, nausea, vomiting, tingling and metallic taste systematic coagulopathy antivenin |
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theophylline
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theophylline used for asthma and bronchospasm. symptoms tachy cardia hypokalemia hyperglycemia< thing btwo activation> treat with betal blocker <propanolo, esmolo phenobarbital for convulsions |