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3 Cards in this Set
- Front
- Back
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Features of Methanol Overdose
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Formic Acid is the metabolite responsible for toxicity.
CNS Depression Metabolic Acidosis Visual Changes Coma, SZ and Metabolic Acidosis are poor prognostic features Signs may be delayed upt to 24hrs Non reactive mydriasis idicates permanent damage |
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Features of Ethylene Glycol Overdose
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GLycolic acid is thought to be the najor contributing toxic metabolite.
CNS depression Metabolic acidosis Renal Failure |
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Toxic alcohol Treatment
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No gastric emptying
Metabolic Blockade - ethanol or fomepizole (indication - unexplained osmolar gap, or metabolic acidosis with + ethanol) Hemodialysis - severe acidosis, visual changes, hemodynamic instability or renal failure Bicarbonate infusions to maintain ph between 7.35-7.45 Folic Acid (Methanol) Pyridoxine, thiamine and magnesium (Ethylene Glycol) |
