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35 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Acetylcholinesterase Inhibitors
Organophosphates |
S&S:
Diarrhea, Urination, Miosis, Bradycardia, Bronchostriction, Excitation (Muscle and CNS) Lacrimation Salivation, Sweating |
Intervention/ ANTIDOTE
: Respiratory support: Atropine 2-Pam (pralidoxime) irreversible AChE Inhibitors |
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Atropine and Muscarinic blockers
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↑HR ↑ BP, Hyperthermia (hot dry skin) delirium, Hallucinations, Mydriasis
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Intervention/ ANTIDOTE
Control CV symptoms and Hyperthermia+ Physostigmine (Cross BBB) |
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Carbon Monoxide Poisoning
>10% Carboxy Hb |
Nausea, vominting dyspnea with Hyperventilation, Mydriasis, vertigo,
CV signs prominent ↓ BP, syncope ↑HR, arrhythmias |
Intervention/ ANTIDOTE
Hyperbaric Oxygen and decontamination Humidifed 100% O2 in mild overdose is ok |
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CNS Stimulants
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Anxiety/agitation, Hyperthermia(warm sweaty skin) MYDRIASIS, ↑HR ↑BP, psychosis, seizure.
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Intervention/ ANTIDOTE
Control CV and hyperthermia symptoms Benzo for seizures |
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OPIODS Analgesic
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Lehtargy, Sedation ↓ HR ↓ BP hypoventilation(resp depression)miosis, coma, respiratory failure
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Intervention/ ANTIDOTE
Ventilatory support Naloxone/natrexone frequent intervals |
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Salicylates (ASA)
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Confusion Lethargy, Hyperventilation,
dehydration hypokalemia Acidosis seizure coma |
Intervention/ ANTIDOTE
Correct acidosis, and electrolytes--> urinary alkalinization possible hemodialysis |
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Sedative/ Hypnotics (BZDs)
ALCOHOL |
Disinhibition, lethargy,ataxia, nystagmus,stupor, coma, hypothermia, respiratory failure
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Intervention/ ANTIDOTE
ventalatory support FLUMAZENIL if BZDs used |
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SSRI
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agitation, curgusion, Hallucination, Muscle rigitidy
Hyperthermia↑HR ↑BP Siezures |
Intervention/ ANTIDOTE
If neuroleptic syndrom use Dantrolene COntrol Hyperthermia and seizures... possible cyproheptadine, antipsychotics |
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Tricyclic Antidepressants
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Mydriasis, Hyperthermia (hot dry skin) 3C's : convulsions coma, cardiotoxicity) _-> arrhythmias
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Control Seiszure and hyperthermia... correct Acidosis and possibly arrhythmia
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Succinyl Choline
Currarine Drugs (tubocurarine) halothane |
MAlignant hyperthermia
Muscle rigidity hyperthermia hypertension, acidosis, hyperkalemia |
Dantrolene Decrease skelatal muscle contractility by blocking Ca release from the sarcoplasmic reticulum
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Arsenic
wood Presevative |
S&S:
Acute: gastroenteritis, hypotension, metabolic acidosis, GARLIC BREATH,"ricewater" stool Torsades Seizures Pallor- skin Pigmentation (rain Drop Pattern) allopecia, stocking glove neuropathy Myelosupression |
Intervention and Antidote
Dimercaprol - Acute Penicillamine- Chronic |
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Copper
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Wilson Disease:
Keiser Fleisher ring... |
Penicillamine
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Iron
Medicinal anemials Prenatal supplements |
Acute; Mainly in kids
sever GI distress--> Necrotizing Gastroenteritis, with Hematemsis bloody diarrhear, Dyspnea, shock, Coma |
Gastric Lavage
DeFEROxamine IV FEROUS--> IRON |
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Lead Poisoning
Tapwater, Lead paintchips, herbal, remedies, gas sniffing, glazed kichenware |
Acute: Nausea and vomiting Gi distress pain, malaise, tremor, Tinnitus, Paraesthesias, encephalopathy (red or black feces)
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Children: Succimer is the treatment
in adults ... Gastric lavage and Dimercaprol, or EDTA |
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Mercury
(elemental in instruments. Salts used as amalgum, battaries, Fish, fireworks electroplating |
Acute vapor inhalation: C/P dyspnea, pneumonitis
Acute: Inorgani salt ingestion- Hemmorhagic gastroenteritis acute Tubular Necrosis Shock |
Dimercaperol
or Succimer |
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Acetominophen
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N-Acetylcystine
Precursor to glutathione |
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Salycilates (ASA)
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Na+ HCO3- (alkalinize Urine) dialysis
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Amphetamines (basic)
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NH4 CL (acidify urine)
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Organophosphates
Acetylcholinesterase inhibitors |
Atropine & Pralidoxime (2-pam)
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Anti-Muscarinic Anticholinergic
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Physostimine Salycilate
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Beta Blocker
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Glucagon
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Digoxin
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stop Dig, Normalize potasium
Lidocain, Anti DIG-Fab Mg2+ |
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Iron
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Deferoxamine
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Mecury, Arsenic, Gold
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Dimercaperol
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Cynaide
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Nitrites & thiosulfate (reducing agent
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Methemoglobin
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Methelyne BLUE
Alternative Vitamin C |
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Carbon Monoxide
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100% Hyperbaric O2
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Methanol, Ethylen Glycol
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Ethanol, dialasis, Fomepizole
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Opiods
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Naloxone (NARCAN)
/Naltrexone |
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Benzodiazapines
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Flumezenil
(ROMAZICON) |
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TCAs
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HCO3-
Plasma alkalinization |
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Heparin
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Protamine
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Warfarin (coumadin)
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Vitamin K
Fresh Frozen Plazma |
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tPA, Streptokinase
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Aminocaproic Acid
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Theophyllin
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Beta blocker
Esmolol |
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