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30 Cards in this Set
- Front
- Back
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topical antifungals agents
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amphotericin b
butenafine butoconazole ciclopirox clioquinol clotrimazole econazole gential violet ketoconazole miconazole naftifine nystatin oxiconazole sulconazole terbinafine terconazole tioconazole tolnaftate |
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amp b use
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oropharyngeal candidiasis
cutaneous and mucocutaneous candidal infxn local irrigant for bladder and intrapleural or intraperitoneal areas |
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butenafine
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synthetic benzylamine realted to the allulamine antifungal agents (naftifine , terbinafine)
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butenafine axn
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alters fungal membrane permeability and growth inhibiton
interferes with sterol biosynthesis by allowing squalene to accumilate with the cell |
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butenafine activity
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tricophyton rubrum
trichophyton mentahrophytes microsporum canis sporothrix schenckii yeasts candida parapsilosis candida albicans |
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butenafine 1% cr
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dermatophytoses
tinea corporis, cruris,pedis |
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butoconazole
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azole antifungal cr
vaginal use |
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butoconazole axn
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fungistatic
interferes w/ membrane permeability, 2ndary metabolic eff and growth inhibition |
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butoconazole activity
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dermatophytes,yeasts g+ org
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butoconazole 2% cr
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vulvovaginal candidiasis
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butoconazole precaution
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avoid using tampoons
damage birth control devices |
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ciclopirox
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synthetic antifungal agent
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ethanolamine in ciclopirox
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enhance epidermal penetration
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ciclopirox axn
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intracellular depletion of amino acid and ions nec fornormal cellular fxn
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ciclopirox activity
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dermatophytes, yeats, g+ and g- bacteria
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ciclopirox use
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tinea pedis,cruris,corporis, versicolor, cutaneous candiciasis (moniliasis) from C albicans
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clioquinol
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topical antifungal
use with hydrocortisone |
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clioquinol activity
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dermatophytic fungi
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clioquinol use
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tinea pedis,cruris (ringworm)
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clotrimazole
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azole antifungal agt that is an imidazole der
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clotrimazole axn
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alters fungal cell membrane permeability by binding with phospholipids in the membrane
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clotimazole activity
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yeast, dermatophytes, g+ bac
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clotrimazole use- lozenges
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oropharyngeal candidiasis
primary prophylaxis of mucocutaneous candidiasis in HIV infected infants or children with severe immunosuppression |
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clotrimazole use - cr,lotion or soln
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dernatiohytoses, superficial mycoses and cutaneous candidiasis
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clotrimazole intravaginal use
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vulvovaginal candidiasis
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econazole
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azole antifungal agt
imidazole deriv |
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econazole axn
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alters cell membranes and inc permeability
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econazole activity
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dermatophytes, yeasts g+ bac and T vaginalis
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econazole 1% top cr,lot,soln
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dermatophytoses
cutaneous candidiasis - tinea corporis,cruris |
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econazole
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treat pityriases (tinea)
vexicolor (M. furfur) |
