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11 Cards in this Set

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Pioglitazone HCl
Actos
Diabetes mellitus
TZD- less hypoglycemic risk/ Thinzolidinedione antidiabetic agent that decreases insulin resistance by improving target cell response to insulin. Binds PPAR that regulates transcription of insulin responsive genes.
May be taken w/o regard to meals. Closely follow dietary/exercise instructions. Quarterly HbA-1c. Store in cool/dry place away from sunlight/children. Do not double doses.
Requires insulin activity, inhibits gluconeogenesis(hepatic), Increases insulin sensitivity. Increase in insulin dependent glucose disposal. Quarterly hba1c test should be taken
Alendronate Sodium
Fosamax
Osteoporosis
Bisphosphonate Adheres to bone resorption sites and Inhibits osteoclasts
Swallowed w/ 6-8 oz of water upon arising in the day(30 min before food/bev, or other meds). Do not lie down for 30 min after swallowing. Report Gi distress. Swallow whole. Do not crush/chew/suck. Do not double doses. Store in a cool/dry place away from sunlight/children.
Very long half life,
Glyburide
Micronase, Diabeta
Diabetes mellitus
Stim insulin synthesis and release from B cells in the pancreatic islets. SulfonylUrea
Store in cool/dry place away from sunlight/children. Do not double doses. Take w/ breakfast or the first main meal. Compliance necessary for optimum effect. Follow diet closely, Avoid excessive alcohol. Patient should be aware of signs of hypoglycemia including sweating/tremor/blurred vision/weakness/hunger/confusion. When 2 or more treat w/oral glucose or contact physician
Insulin secretagogue
Ibandronate
Boniva
Osteoporosis (prevention and treatment)
Bisphosphonate Inhibits osteoclasts
Take 60 min before food/drink(except H20). Take in upright position. Do not lie down for 60 min after admin. Swallow tablets whole. Do not chew/dissolve in mouth. Supp Ca or Al taken at diff time of day. Contact Dr. if diff pain swallowing/ heartburn occur. Do not take 2 tablets on the same day. If monthly dose is missed, skip and return to daily dosing. Do not take 2 tabs w/i 7 days. Store in cool/dry place from sunlight/children.
Take 60 min before eating.
Sitagliptin
Januvia
Diabetes mellitus
DPP inhibitor (DPP deactivates GLP(glucagon like peptide-1) and GIP(glucose dependent insulinotropic polypeptide. These hormones are released by intestine and increase insulin synthesis and release from Panc b-cells.
Take w/o regard to meals. Follow dietary/exercise. Quarterly HbA-1c testing. Store cool/dry place from sunlight/children. Do not double doses.
Insulin glargine
Lantus
Diabetes mellitus
Long acting recombinant human insulin (up to 24 hrs). Insulin-proper glucose use and transport.
Follow diet/ Do not change insulin brands, syringe or dose w/o physician. Consult a physician during any illness. DO NOT DILUTE or mix Lantus with any other insulin/soln. Should be clear and colorless with no visible particles.If does missed, take asap. Be aware of hypoglycemia warning signs.
Storage requirements: Unopened-refrig, do not freeze. Can be at room temp for 28 days. Opened vials discard after 28 days.
Levothyroxine Sodium
Synthroid, Levoxyl, Levothroid
Hypothyroidism
Unknown- but protein synthesis control 1)reg growth 2)increase in metabolic rate 3)inhib of thyrotropin in pituitary 4)lipid effects.
Do not discontinue w/o physician. Notify Dr. for signs of hyperthyroidism. Transient loss of hair seen in children, but recovery usually occurs. Store n cool/dry place from sunlight/children. Do not double doses.
Narrow therapeutic window
Metformin HCl
glucophage
Diabetes mellitus
biguanide- improves glucose tolerance. Decreases intestinal abs of glucose, suppress hepatic gluconeogenesis, and improves insulin sensitivity.
Should be taken w/meals. Avoid excess alcohol. Follow diet/exercise. Stop tx if symptoms- hyperventilation, myalgia, malaise, or unusual somnolence. Do not double doses. Keep well hydrated-plenty of fluids.
XR- tablet may be found in the stool as soft-hydrated mass.
Raloxifene
Evista
Osteoporosis (prevention and treatment)
SERM- Decreases bone resorption by producing estrogen-like affect on bone.(Also decrease in LDL levels)
Discontinue 72 hrs prior to periods of prolonged immobilization. Avoid prolonged restrictions of movement during travel. Take Ca or vit D supp if intake is inadequate. Report any signs of blood clots. These include pains in calves or leg swelling, sudden chest pain, shortness of breath or coughing blood, changes in vision. Discontinue if pregnancy is suspected. Store in cool/dry place from sunlight/children. If dose missed, take asap and return to normal sched.
Possibility of hot flashes.
Risedronate
Actonel
Osteoporosis (prevention and treatment)
Bisphosphonate Inhibits osteoclasts
Take at least 30 minutes before first food/drink other than H20. Take in an upright position w/ full glass of water. Do not lie down for 30 min after admin. Swallow tablets whole. Do not chew/dissolve. Supp calc, magnesium, or Al taken at diff time of day. Contact Dr. if pain swallowing, heartburn(esophageal disease). Do not take 2 tablets on the same day. If weekly/monthly missed take it on the morning after remembering the missed dose and return to normal sched.
Vitamin D
Drisdol
Vitamin D deficiency
Proper regulation of Ca in plasma and activity of parathyroid hormone. Bone mineralization.
Take w/o regard to meals. Follow prescribed Ca supp. Do not exceed dosage. Store cool/dry place away from any light and children. If dose is missed, skip and return to normal sched.
Used in rickets. Very high dose, 50,000 units.