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127 Cards in this Set

  • Front
  • Back
Breath Right Strips
SNORE AID

DOSAGE: nasal strips ;
MOA: open nasal passage ;
INDICATIONS: snoring and congestion ;
ADRs: Rash, skin irritation
Lactaid (lactose)
LACTOSE INTOLERANCE

DOSAGE: oral caplets (tablet, chewable) - 3 caps upon consumption of dairy
MOA: enzyme in hydrolysis of disaccharide lactose into constituent galactose and glucose monomers
INDICATIONS: lactose intolerance (gas, cramps, bloating, diarrhea)
Imodium AD (loperimide)
ANTIDIARRHEAL

DOSAGE: 2mg tablet (MAX-16mg/day
MOA: slows intestinal motility and inhibits fluid and electrolyte secretion
INDICATIONS: diarrhea
ADRs: abdominal pain, constipation
COUNSEL: do not use if diarrhea is black/bloody
Cold-EEZE (zinc)
SUPPLEMENT

DOSAGE: lozenges (dissolve in the mouth)
MOA: +ions that bind to neg. charged rhinovirus, prevents replication
INDICATIONS: common cold
ADRs: temp change in taste buds, mild stomach upset
Ocuvite (Lutein)
SUPPLEMENT

DOSAGE: oral tablets (2mg & 6mg lutein) qd or bid
MOA: powerful antioxidant, protects against UV damage by filtering blue light
INDICATIONS: eye care
AZO Cranberry (cranberry, probiotic lactobacillus, vit c)
UTI PREVENTION

DOSAGE: oral tablets (2tabs w/ H2O, max 6tabs/day)
MOA: blocks the attachment of bacteria to the bladder wall
INDICATIONS: urinary tract infections
ADRs: diarrhea, GI symptoms
Bactroban (mupirocin)
WOUND CARE

DOSAGE: ointment (clean area, coat and cover)
MOA: inhibits protein synthesis
INDICATIONS: impetigo, skin lesions, dermatitis
ADRs: burning, stinging, pain, itching
Neosporin (neomycin)
WOUND CARE

DOSAGE: ointment (clean area, coat and cover)
MOA: inhibits protein synthesis, good against gram neg bacilli
INDICATIONS: antibiotic and pain reliever for minor cuts, scrapes, burns
ADRs: itching, swelling, local irritation
Bacitracin
WOUND CARE

DOSAGE: ointment (clean area, coat and cover)
MOA: antibacterial against staph infections
INDICATIONS: antibiotic & pain reliever for minor cuts, scrapes, burns
Polymyxin B
WOUND CARE

DOSAGE: ointment (clean area, coat and cover)
MOA: increases bacterial cell membrane permeability
INDICATIONS: antibiotic & pain reliever for minor cuts, scrapes, burns
Monistat (miconazole)
ANTIFUNGAL

DOSAGE: Cream(2%), Suppositories(100mg)
MOA: inhibits biosynthesis of ergosterol, damages fungal cell wall & alters permeability
INDICATIONS: vaginal yeast infections
ADRs: stomach and vaginal discomfort
COUNSEL: avoid other vaginal products
Abreva (docosanol)
COLD SORES

DOSAGE: topical cream 10%
MOA: reduces viral replication & inhibits fusion of plasma membrane and HSV envelope
INDICATIONS: oral herpes or cold sores
ADRs: application site reaction, headache
COUNSEL: for herpetic lesions on lips and face only
Baby Orajel (benzocaine 7.5%)
TEETHING PRODUCT

DOSAGE: oral gel, liquid, swabs
MOA: local anesthetic decreases Na ion permeability thru reversible stabilization of neuronal membrane
INDICATIONS: teething pain for babies
ADRs: swelling, fever, rash, mouth irritation
COUNSEL: wash hands before use
NIX (permethrin)
LICE TREATMENT

DOSAGE: topical liquid 1%
MOA: acts on nerve cell membrane of louse to disrupt Na channel current that regulates polarization, leads to paralysis
INDICATION: head lice, scabies
ADRs: pruritus, burning, stinging
COUNSEL: avoid mucous membranes
Afrin (oxymetazoline)
DECONGESTANT

DOSAGE: nasal spray 0.05% (no more than 3 days)
MOA: constricts blood vessels in nose/sinuses leads to drainage
INDICATIONS: nasal congestion
COUNSEL: avoid MAO inhibitors or CNS depressants
Mederma
SCAR TREATMENT

DOSAGE: topical gel (20 & 50g tube) - tid x8w
MOA: improve color, texture and over appearance of old and new scars
INDICATION: scar treatment
ADRs: itching, burning, discoloration
Sensodyne (potassium Nitrate 5% - antihypersensitivity or sodium fluoride 0.13% - anticavity)
TOOTHPASTE

DOSAGE: paste
MOA: desensitizes nerve endings within tubules found in dentin, makes them less responsive to hot, cold, etc
INDICATIONS: tooth sensitivity
COUNSEL: do not swallow
Mucinex (guaifenesin)
EXPECTORANT

DOSAGE: tablet er (600, 1200mg)
MOA: increase volume and reduces viscosity of secretions
INDICATIONS: abnormal sputum production
ADRs: n/v
COUNSEL: take w/ full glass of water
Debrox (carbamide peroxide)
EAR WAX REMOVAL

DOSAGE: otic soln 6.5% - 5-10gtts bid
MOA: releases oxygen, softens and loosens wax
INDICATIONS: removal of ear wax
Colace (docusate sodium)
STOOL SOFTENER

DOSAGE: capsule(50mg, 100mg), liquid(150mg/15ml, 100mg/10ml)
MOA: draws water into stool
INDICATION: constipation
ADRs: bitter taste, diarrhea, nausea, cramps
COUNSEL: works in 12-72hrs, drink water
Miralax (polyethylene glycol)
LAXATIVE

DOSAGE: powder for soln (17gm/dose)
MOA: causes retention of water in stool
INDICATION: constipation
ADRs: diarrhea, flatulence, nausea, stomach cramps
Lamisil AT (terbinafine)
ANTIFUNGAL

DOSAGE: topical spray(1%), topical cream(1%)
MOA: inhibits biosynthesis of ergosterol in fungal cell membrane
INDICATION: fungal infection, athletes foot
ADRs: stinging, burning, dryness
Maalox (calcium carbonate)
ANTACIDS

MOA: absorbed in GI tract via passive diffusion
INDICATION: acid indigestion, heartburn, upset stomach
ADRs: GI irritation
Mylanta (aluminum hydroxide & magnesium hydroxide)
ANTACIDS

MOA: increase lower esophageal sphincter tone, neutralize gastric acid
INDICATION; uncomplicated peptic ulcer, gastric hyperacidity
ADRs: constipation
Benadryl (diphenhydramine)
ANTIHISTAMINE - 1st generation

DOSAGE: iv(50mg/ml), caps(25mg), tablet(25mg)
MOA: competes with histamine for H1 receptor
INDICATION: allergic rhinitis, common cold
ADRs: drowsiness(used in sleep aids)
Allegra (fexofenadine)
ANTIHISTAMINE - 2nd generation

DOSAGE: caps(60mg), Susp(30mg/5ml), tab(30,60,180mg)
MOA: inhibits release of histamine from mast cells and antagonizes H1 receptor
INDICATION: seasonal allergic rhinitis
ADRs: dyspepsia, dizziness, headache, drowsy, fatigue
COUNSEL: do not take with fruit juices
Zyrtec (cetirizine)
ANTIHISTAMINE - 2nd generation

DOSAGE: syrup(1mg/ml), tab(5,10mg), chew(5,10mg)
MOA: inhibits H1 receptors
INDICATION: perennial and seasonal allergic rhinitis
ADRs: dry mouth, headache, drowsiness, fatigue
Clarinex (desloratadine)
ANTIHISTAMINE - 2nd generation

DOSAGE: syrup(0.5mg/ml), tab(5mg)
MOA: tricyclic histamine antagonist w/ H1 receptor antagonist activity
INDICATION: perennial & season allergic rhinitis
ADRs: dry mouth, muscle weakness, drowsiness, fatigue, flu-like
Patanol (olopatadine)
ANTIHISTAMINE - OCULAR

DOSAGE: eye drop(0.1%)
MOA: H1 antagonist, inhibits release of histamine
INDICATIONS: allergic conjuctivitis
ADRs: altered taste, headache, burning in eye
Promethazine
ANTIEMETIC/ANTIVERTIGO

DOSAGE: tab(25mg)
MOA: blocks H1 receptors w/out blocking secretion of histamine
INDICATION: motion sickness, vertigo, N/V
ADRs: unstable BP, dizziness, sweating
COUNSEL: avoid excessive sunlight, MAOIs
Antivert (meclizine)
ANTIEMETIC/ANTIVERTIGO

DOSAGE: tab(25,50mg)
MOA: suppresses vasodepressor response to histamine & only slightly inhibit ACh
INDICATION: motion sickness, vertigo, radiation-induced n/v
ADRs: sedation, dry mouth
COUNSEL: take 1 hour before travel
Allegra D (fexofenadine/PSE)
ANTIHISTAMINE/DECONGESTANT COMBO

DOSAGE: tab er(60mg/120mg)
MOA: fex-inhibits release of histamine, pse-decongestant on nasal mucosa
INDICATION: seasonal allergic rhinitis
ADRs: palpitations, abdominal pain, nausea, headache, insomnia
Nasonex (mometasone)
INTRANASAL STEROID

DOSAGE: nasal spray(0.05mg/actuation--17g 120metered doses)
MOA: antiinflammatory, antipruritic, vasoconstrictor--inhibit release of arachidonic acid, inhibit phospholipase A2
INDICATION: Allergic rhinitis
ADRs: dyspepsia, back pain, headache, pharyngitis
Nasacort AQ (triamcinolone)
INTRANASAL STEROID

DOSAGE: nasal spray(55mcg/actuation--16.5g bottle)
MOA: antiinflammatory, antipruritic--changes body's immune responses
INDICATION: allergic rhinitis
COUNSEL: shake before using, don't blow nose for 15 minutes after use
Flonase (fluticasone)
INTRANASAL STEROID

DOSAGE: nasal spray(0.05mg/actuation
MOA: antiinflammatory--affects different cells involved in inflammation
INDICATION: allergic rhinitis
ADRs: phryngeal candidiasis, epistaxis, pharyngitis
COUNSEL: shake gently before use
Rhinocort AQ (budesonide)
INTRANASAL STEROID

MOA: acts on different cells involved in inflammation
INDICATION: allergic rhinitis
Naprosyn (naproxen)
NSAID

DOSAGE: susp(25mg/ml), tab(250,375,500mg) OTC(600mg)
MOA: inhibits prostaglandin production
INDICATION: pain & inflammation, headache, fever

*EFFECT OF FOOD-increases Tmax to 12hrs
**BLACK BOX**-increase risk of CV thrombotic events, MI, stroke
Motrin (ibuprofen)
NSAID

DOSAGE: susp(100mg/5ml), tab(400,600,800), otc(200mg)
MOA: inhibits prostaglandin synthesis
INDICATION: pain, inflammation, headache, fever
*MAX=1200mg/day
**BLACK BOX**-increase risk of CV thrombotic events, MI, stroke
Mobic (meloxicam)
NSAID

DOSAGE: susp(7.5mg/5ml), tab(7.5,15mg)
MOA: inhibit COX pathway
INDICATION: osteoarthritis, RA
ADRs: HTN, edema, ab pain, diarrhea, flatulance, nausea, headache, dizziness
**BLACK BOX**-increase risk of VC thrombotic events, MI, stroke
Celebrex (celecoxib)
NSAID - COX 2 INHIBITOR

DOSAGE: caps(50,100,200,400mg)
MOA: inhibits COX 2, decreased prostaglandins
INDICATION: osteoarthritis, RA, acute pain
COUNSEL: don't use if allergic to ASA, sulfonamides, NSAIDS
Ultram (tramadol)
NARCOTIC ANALGESIC

DOSAGE: tab(50mg)--max dose(400mg/day)
MOA: binds to m-opioid receptor, inhibits reuptake of serotonin and NE
INDICATION: moderate pain
ADRs: dizziness, nausea, constipation
Tylenol #3 (acetaminophen w/ codeine)
NARCOTIC ANALGESIC COMBO

DOSAGE: tab(30mg/325mg) max(12tabs/day)
MOA: codeine-centrally acting analgesic ; APAP-inhibits prostaglandin synthesis
INDICATION: mild-moderately severe pain
COUNSEL: apap overdose(4g/day)
Vicodin (hydrocodone/apap)
NARCOTIC ANALGESIC COMBO

DOSAGE: tab(5mg/500mg) max(8tabs/day)
MOA: apap-antipyretic & analgesic ; hydrocodone-opioid analgesic
INDICATION: moderate-severe pain
**BLACK BOX**-apap=acute liver failure
Norco (hydrocodone/apap)
NARCOTIC ANALGESIC COMBO

DOSAGE: tab(5/325, 7.5/325, 10/325)
MOA: apap-antipyretic & analgesic ; hydrocodone - opioid analgesic
INDICATION: moderate-severe pain
**BLACK BOX**-apap=acute liver failure
Percodan (oxycodone/asa)
NARCOTIC ANALGESIC COMBO

DOSAGE: tab(4.8/325) max(12tabs/day)
MOA: oxycodone-pure opioid agonist ; asa-antipyretic & analgesic
INDICATION: moderate-severe pain
ADRs: dizziness, nausea
Percocet (oxycodone/apap)
NARCOTIC ANALGESIC COMBO

DOSAGE: tab(2.5,5,7.5,10/325 , 7.5/500, 10/650mg) max(12, 8, 6 tabs/day respectively)
MOA: apap-nonopiate antipyretic & analgesic ; oxycodone-sedation and analgesia
INDICATION: moderate-moderately severe pain
ADRs: dizziness, drowsiness, nausea
**BLACK BOX**-apap=acute liver failure
Flexeril (cyclobenzaprine)
SKELETAL MUSCLE RELAXER

DOSAGE: tab(5,10mg)
MOA: influences gamma and alpha motor systems by reducing tonic somatic motor activity
INDICATION: skeletal muscle spasm
ADRs: bad taste in mouth, anticholinergic effects, nausea, headache
Imitrex (sumatriptan)
ANTIMIGRAINE - 5HT receptor agonist

DOSAGE: tab(25,50,100mg) subq(6mg/0.5ml) max(200mg/day tab, 12mg/day subq)
MOA: 5HT receptor agonist
INDICATION: migraine, cluster headache
ADRs: subq=tingling, warm sensation, flushing, dizziness, vertigo
Xalatan (latanoprost)
GLAUCOMA AGENT - OPHTHALMIC

DOSAGE: soln(2.5ml)
MOA: reduces intraocular pressure by increasing outflow of aqueous humor
INDICATION: glaucoma
ADRs: blurred vision, burning/stinging, darkening of iris and eyelid
STORAGE: cool, dark place or fridge
Travatan (travaprost)
GLAUCOMA AGENT - eye drop

MOA: reduces intraocular pressure by increasing outflow of aqueous humor
INDICATION: glaucoma
ADRs: ocular hyperemia, eye discomfort
STORAGE: cool, dry place away from light
Lumigan (bimatoprost)
GLAUCOMA AGENT - eye drop

MOA: selectively mimics natural prostamides
INDICATION: open-angle glaucoma, ocular htn
ADRs: ocular hyperemia
STORAGE: cool, dry place away from light
Amoxil (amoxicillin)
PENICILLIN ANTIBIOTIC

DOSAGE: susp(125/5,200/5,250/5,400/5) tabs(875mg) chew(125mg,250mg,400mg)
MOA: bacteriocidal-inhibits cell wall synthesis
INDICATION: bacterial infections, otitis media
ADRs: n/v/d, irritation of mouth or throat
COUNSEL: reduce effectiveness of OC
Pen VK (penicillin)
PENICILLIN ANTIBIOTIC

DOSAGE: tab(250,500mg) susp(125mg/5ml, 250mg/5ml)
MOA: bactericidal-inhibits cell wall synthesis
INDICATION: bacterial infections, otitis media
ADRs: black-hairy tongue, mild n/v/d, upset stomach
COUNSEL: reduce effectiveness of OC
Augmentin (amox/clav)
COMBO ANTIBIOTIC

DOSAGE: tab(500/125mg,875/125mg,250/125mg) susp(200/5ml, 400/5ml), chew(400mg)
MOA: bactericidal-inhibits cell wall synthesis & beta-lactamase
INDICATION: bacterial infections, otitis media
ADRs: n/v/d
**Clav=beta-lactamase..fights PCN resistant bacteria
Keflex (cephalexin)
CEPHALOSPORIN ANTIBIOTIC

DOSAGE: cap(250,500mg) susp(125/5ml, 250/5ml)
MOA: bactericidal-inhibits cell wall synthesis
INDICATION: bacterial infection, otitis media, UTI
ADRs: dizziness, tiredness, headache, diarrhea
**% of patients w/ PCN allergy allergic to cephs-10%
Omnicef (cefdinir)
CEPHALOSPORIN ANTIBIOTIC

DOSAGE: cap(300mg) susp(125/5ml, 250/5ml)
MOA: bactericidal-inhibits cell wall synthesis
INDICATION: bacterial infection, otitis media, UTI
ADRs: n/v/d, headache
**interaction w/ antacids = decreased absorption of antibiotic
Levaquin (levofloxacin)
FLUOROQUINOLONE ANTIBIOTIC

DOSAGE: tab(250,500,750mg), soln(25mg/ml)
MOA: inhibits DNA gyrase & topoisomerase IV
INDICATION: bacterial infections, prevent/slow anthrax, UTI
ADRs: constipation, n/d, gas, headache
BLACK BOX WARNING FOR FLUOROQUINOLONES
increase tendonitis/tendon rupture risk in all ages
Cipro (ciprofloxacin)
FLUOROQUINOLONE ANTIBIOTIC

DOSAGE: tab(250,500,750) susp(5g/100ml) XR(500,100)
MOA: inhibits DNA gyrase & topoisomerase IV
INDICATION: bacterial infections, prevent/slow anthrax, UTI
ADRs: n/v/d, dizziness, headache, loss of appetite
Avelox (moxifloxacin)
FLUOROQUINOLONE ANTIBIOTIC

DOSAGE: tab(400mg), IV
MOA: inhibits topoisomerase II and IV
INDICATION: bacterial infections
ADRs: dizziness, n/v/d
Zithromax (azithromycin)
MACROLIDE ANTIBIOTIC

DOSAGE: tab(250,500mg) susp(100/5ml, 200/5ml)
MOA: binds to P site of 50S ribosomal subunit, interferes w/ protein synthesis
INDICATION: bacterial infections, otitis media
ADRs: mild n/d, headache, stomach pain
what is dosage regimen of azithromycin in Community Acquired Pneumonia in adults?
500mg stat, 1250mg days 2-5 OR 500mg IV x2 or more days, then 500mg PO days 7-10
Doxyclycline Hyclate
TCN ANTIBIOTIC

DOSAGE: cap(50,100mg) tab(20,100mg)
MOA: inhibits protein synthesis and collagenase activity
INDICATION: uti, acne, gonorrhea, chlamydia
ADRs: n/v, loss of appetite, *photosensitivity*
OFF LABEL USE: rosacea
Doryx (doxycycline)
TCN ANTIBIOTIC

DOSAGE: tab(50,75,100) cap(150)
MOA: inhibits protein synthesis
INDICATIONS: bacterial infections, acne
ADRs: headache, n/v, dizziness
**enteric coated-less GI upset*
Bactrim (sulfa-trimeth)
SULFA COMBO ANTIBIOTIC

DOSAGE: tab(400/80mg, 800/160mg), susp
MOA: inhibits PABA utilization & interfere w/ dihydrofolate reductase
INDICATION: uti, pcp
ADRs: n/v, loss of appetite, stomach upset, *photosensitivity*
Valtrex (valcyclovir)
ANTIVIRAL AGENT

DOSAGE: tab(500,1000mg)
MOA: inhibits DNA polymerase
INDICATION: herpes zoster, cold sores, genital herpes, chicken pox
ADRs: n/v, dizziness, headache, stomach pain
Zovirax (acyclovir)
ANTIVIRAL AGENT

DOSAGE: tab(400,800mg) cap(200mg) susp, oint, crm
MOA: inhibits DNA polymerase
INDICATION: oral and genital herpes, cold sores
ADRs: caps/tabs=n/v, oint/crm=sting, burning, itch
Tamiflu (oseltamivir)
ANTIVIRAL AGENT

DOSAGE: cap(30,40,75mg) susp
MOA: inhibit influenza virus neuraminidase
INDICATION: uncomplicated acute illness due to influenza
ADRs: n/v
How is Tamiflu dosed regularly? How is it dosed to treat the flu?
1. 75mg QD x10D
2. 75mg BID x5D
Diflucan (fluconazole)
ANTIFUNGAL

DOSAGE: tab(50,100,150,200mg) susp(10mg/ml, 40mg/ml)
MOA: inhibit cyp 450 & sterol C14
INDICATION: fungal infections
ADRs: headache, n/v/d, stomach upset, taste, dizziness
Synthroid (levothyroxine) & Levoxyl
THYROID HORMONE

DOSAGE: tab(25,50,75,88,100,112,137,150,175,200,300mcg)
MOA: synthetic T4
INDICATION: low thyroid hormone levels, goiters
Yasmin (drospirenone & ethinyl estradiol) & Yaz
ORAL CONTRACEPTIVE

DOSAGE: tab(21drug + 7 placebos)
MOA: suppress LH & FSH, inhibit ovulation
INDICATION: prevent pregnancy, moderate acne
ADRs: bleeding/spotting, breast tenderness, cramps, n/v
BLACK BOX WARNING FOR ORAL and TOPICAL CONTRACEPTIVES
along with smoking, increases risk of heart problems, cardiovascular and thromboembolic disorders
Ortho Tri-Cyclen (Norgestimate & ethinyl estradiol) &
Tri-Sprintec (Norgestimate & ethinyl estradiol) &
Tri-Nessa
ORAL CONTRACEPTIVE

DOSAGE: 28tabs(21drug + 7 placebos)
MOA: suppress LH and FSH, inhibit ovulation
INDICATION: prevent pregnancy, moderate acne
ADRs: n/v, bleeding, breast tenderness
Plan B (levonorgestrel) & Next Choice (levonorgestrel)
EMERGENCY ORAL CONTRACEPTIVE

DOSAGE: tab(1.5mg) & tab(0.75mg)
DIRECTIONS: 1t po w/in 72hrs, next one in 12hrs
MOA: prevents ovulation, fertilization, implantation
INDICATION: prevent pregnancy after contraception failure
ADRs: fatigue, headache, dizziness
Age at which Plan B and Next Choice can be dispensed without a prescription?
17 years old or older
Ortho-Evra (Norelgestromin & ethinyl estradiol)
TOPICAL CONTRACEPTIVE

DOSAGE: patch
MOA: suppress LH & FSH, inhibit ovulation
INDICATION: prevent pregnancy
ADRs: breast tenderness, headache, cramps, n/v, bloating, spotting
Nuvaring (Etonogestrel & ethinyl estradiol)
CONTRACEPTIVE VAGINAL RING

DOSAGE: vaginal ring
MOA: suppress LH and FSH, inhibit ovulation
INDICATION: prevent pregnancy
ADRs: breast tenderness, dizziness, weight gain, headache, mild hair loss, spotting, bloating
***ALLOW 1 WEEK TO PASS BEFORE INSERTING NEW RING***
Premarin (conjugated estrogen)
ESTROGEN

DOSAGE: tab(0.3, 0.45,0.625,0.9,1.25mg) crm
MOA: binds to estrogen receptors
INDICATION: decrease menopausal symptoms
ADRs: tab=dizziness, gas, nausea ; crm=dizziness, nausea, vaginal buring
Fosamax (alendronate)
BISPHOSPHONATE

DOSAGE: weekly(35,70), daily(5,40,70)
MOA: inhibit osteoclast activity reducing bone resorption
INDICATION: prevent & treat osteoporosis
ADRs: constipation, diarea, dizziness, bloated, gas, headache
IMPORTANT COUNSELING POINT FOR BISPHOSPHONATES
stay upright for 30mins after taking medication to prevent esophageal irritation
Actonel (risedronate)
BISPHOSPHONATE

DOSAGE: weekly(35mg) daily(5,35,75) month(150mg)
MOA: inhibits osteoclast activity
INDICATION: prevent osteoporosis
ADRs: back pain, constipation, diarrhea, dizziness, headache
Boniva (ibandronate)
BISPHOSPHONATE

DOSAGE: monthly(150mg), IV
MOA: inhibit osteoclast activity
INDICATION: prevent osteoporosis
ADRs: dyspepsia, diarrhea
Evista (raloxifene)
SELECTIVE ESTROGEN RECEPTOR MODULATOR

DOSAGE: tab(30mg)
MOA: binds estrogen receptors
INDICATION: post-menopausal osteoporosis
ADRs: hot flashes, infection, flu-like symptoms, nausea, weight gain, cough
Zantac (ranitidine)
H2 BLOCKER

DOSAGE: tab(150, 300) syrup
MOA: blocks histamine release, inhibits H2 receptor
INDICATION: ulcers, GERD
ADRs: constipation, n/d, headache
Pepcid (famotidine)
H2 BLOCKER

DOSAGE: tab(20,40mg)
MOA: blocks histamine release, inhibits H2 receptor
INDICATION: ulcers, GERD
ADRs: constipation, headache, n/d
Aciphex (rabeprazole)
PROTON PUMP INHIBITOR

DOSAGE: tab(20mg)
MOA: inhibits gastric parietal cell, blocks acid production
INDICATION: ulcers, GERD, erosive esophagitis
ADRs: diarrhea, headache
COUNSEL: take 30min before food
Nexium (esomeprazole)
PROTON PUMP INHIBITOR

DOSAGE: cap(20,40mg)
MOA: inhibits gastric parietal cell, blocks acid production
INDICATION: ulcers, GERD, erosive esophagitis
ADRs: constipation, n/d, dry mouth, gas, headache
Prevacid (lansoprazole)
PROTON PUMP INHIBITOR

DOSAGE: cap(15,30) solutab(15,30) granules(15mg)
MOA: inhibits gastric parietal cell, blocks acid production
INDICATION: ulcers, GERD, erosive esophagitis
ADRs: constipation, diarrhea
Prilosec (omeprazole)
PROTON PUMP INHIBITOR

DOSAGE: cap(10,20,40)
MOA: blocks acid production in stomach
INDICATION: ulcers, heartburn, GERD
ADRs: headache, constipation, cough, dizziness
Protonix (pantoprazole)
PROTON PUMP INHIBITOR

DOSAGE: tab(20,40mg) inj(40)
MOA: blocks acid production in stomach
INDICATION: ulcers, GERD, erosive esophagitis
ADRs: headache, n/v/d, stomach pain
Lantus (insulin glargine)
INSULIN - BASAL

DOSAGE: vial(100units) cartridge(100u/ml
MOA: stimulate glucose uptake, inhibit hepatic glucose production
INDICATION: diabetes
ADRs: redness, swelling or itching @ inj site, *HYPOGLYCEMIA*

DURATION: over 24 hours
Levemir
INSULIN - BASAL

DOSAGE: vial(100u) flexpen
MOA: stimulate glucose uptake, inhibit hepatic glucose production
INDICATION: diabetes
ADRs: pain @ inj site, *HYPOGLYCEMIA*

ONSET: 6-8hrs DURATION: 5.7-23hrs
Humulin N & Novolin N
INSULIN - BASAL

DOSAGE: NPH(N), vial(injection)
MOA: decreases formation of TGs
INDICATION: diabetes
ADRs: pain @ site, *HYPOGLYCEMIA*

ONSET: 3-4hrs DURATION: 24hrs
Humulin R & Novolin R
INSULIN - BOLUS

DOSAGE: injection(vial)
MOA: decreases formation of TGs
INDICATION: diabetes
ADRs: pain @ injection site, *HYPOGLYCEMIA*

ONSET: 0.5-1hr DURATION: 6-8hrs
NOVOLOG
INSULIN - BOLUS

DOSAGE: injection(70/30)
MOA: stimulate glucose uptake, inhibit hepatic glucose production
INDICATION: diabetes
ADRs: pain @ injection site, *HYPOGLYCEMIA*

ONSET: 40-50mins DURATION: 80mins
Humalog
INSULIN - BOLUS

DOSAGE: injection(mix=75/25, 50/50)
MOA: stimulate glucose uptake, inhibit hepatic glucose production
INDICATION: diabetes
ADRs: pain @ injection site, *HYPOGLYCEMIA*

ONSET: 30-90mins DURATION: 26-52mins
Apidra
INSULIN - BOLUS

DOSAGE: injection
MOA: stimulate glucose uptake, inhibit hepatic glucose production
INDICATION: diabetes
ADRs: pain @ injection site, *HYPOGLYCEMIA*

DURATION: 42-86mins
Micronase (glyburide)
SULFONYLUREA

DOSAGE: tab(1.25,2.5,5mg)
MOA: stimulate pacreatic islet beta cell insulin release
INDICATION: type 2 diabetes
ADRs: stomach fullness, heartburn, nausea
Glucatrol ER (glipizide er)
SULFONYLUREA

DOSAGE: tab(5,10) xl(2.5,5,10)
MOA: stimulate pancreatic islet beta cell insulin release
INDICATION: type 2 diabetes
ADRs: diarrhea, dizziness, gas, nausea
COUNSEL: take 30mins before meals
Amaryl (glimeperide)
SULFONYLUREA

DOSAGE: tab(1,2,4mg)
MOA: stimulate pancreatic islet beta cell insulin release
INDICATION: type 2 diabetes
ADRs: dizziness, headache, nausea, *HYPOGLYCEMIA*
COUNSEL: take w/ 1st main meal
Glucophage (metformin)
BIGUANIDE

DOSAGE: tab(500,850,1000mg) er(500,750mg)
MOA: decrease hepatic glucose production
INDICATION; type 2 diabetes
ADRs: n/v/d, gas, headache, indigestion, stomach upset, metallic taste
BLACK BOX WARNING FOR METFORMIN
lactic acidosis can occur
Actos (pioglitazone)
THIAZOLIDINEDIONE

DOSAGE: tab(15, 30, 45mg)
MOA: increases insulin sensitivity
INDICATION: type 2 diabetes
ADRs: fluid retention, edema, weight gain, headache, anemia
Januvia (sitagliptin)
DPP-4 INHIBITOR

DOSAGE: tab(25,50,100mg)
MOA: deactivates incretin hormones glucagon like peptide 1
INDICATION: type 2 diabetes
ADRs: nasopharyngitis
RENAL DOSAGE: moderate=50mg, severe=25mg
Onglyza (saxagliptin)
DPP-4 INHIBITOR

DOSAGE: tab(2.5,5mg)
MOA: deactivates incretin hormones glucagon-like peptide 1
INDICATION: type 2 diabetes
ADRs: UTI, headache
RENAL DOSE: 2.5mg/day
Trajenta (linagliptin)
DPP-4 INHIBITOR

DOSAGE: tab(5mg)
MOA: deactivates incretin hormones glucagon-like peptide 11
INDICATION: type 2 diabetes
ADRs: nasopharyngitis
RENAL DOSE: none
Byetta (exenatide - BID)
GLUCAGON-LIKE PEPTIDE-1 AGONIST

DOSAGE: injection
MOA: mimics action of incretins, increase glucose-dependent synthesis and secretion
INDICATION: type 2 diabetes
ADRs: n/v/d, *HYPOGLYCEMIA*
COUNSEL: take w/in 60mins of meal
Victoza (liraglutide)
GLP- 1 AGONIST

DOSAGE: subq injection(18mg/3ml)
MOA: mimics action of incretins, increase glucose-dependent synthesis and secretion
INDICATION: type 2 diabetes
ADRs: n/v/d
BLACK BOX WARNING FOR VICTOZA AND BYDUREON
thyroid C-cell tumor risk
Bydureon (exenatide - QW)
GLP-1 AGONIST

DOSAGE: subq injection(2mg)
MOA: mimics action of incretins, increase glucose-dependent synthesis and secretion
INDICATION: type 2 diabetes
ADRs: n/d, nodule at injection site, *HYPOGLYCEMIA*
Flomax (tamsulosin)
BPH AGENT-ALPHA-1 BLOCKER

DOSAGE: cap(0.4mg)
MOA: antagonize prostate alpha-1-adrenergic receptors, relax smooth muscle
INDICATION: BPH
ADRs: back pain, blurred vision, cough, diarrhea, dizziness, weakness
Viagra (sidenafil)
PDE 5 INHIBITOR

DOSAGE: tab(25,50,100mg)
MOA: inhibits PDE 5, enhances nitric oxide
INDICATION: erectile dysfunction
ADRs: diarrhea, dizziness, flushing, headache, stuffy nose, upset tummy
What happens if Viagra and Cialis are taken with Nitrates?
hypotensive effects
Cialis (tadalafil)
PDE-5 INHIBITOR

DOSAGE: tab(2.5,5,10,20mg)
MOA: inhibits PDE 5, enhances nitric oxide
INDICATION: erectile dysfunction
ADRs: headache, flushing, nausea, heartburn
Detrol LA (tolteradine)
ANTICHOLINERGIC

DOSAGE: cap(2,4mg)
MOA: antagonizes ACh receptors
INDICATION: overactive bladder
ADRs: blurred vision, constipation, dry mouth, drowsiness, headache
Enablex (darifenacin)
ANTIMUSCARINIC

DOSAGE: tab(7.5, 15mg)
MOA: competitive muscarinic receptor antagonist
INDICATION: overactive bladder
ADRs: dry mouth, constipation, blurred vision
Zyloprim (allopurinol)
XANTHINE OXIDASE INHIBITOR

DOSAGE: tab(100,300mg)
MOA: inhibits xanthine oxidase, interferes w/ production of uric acid
INDICATION: gout
ADRs: skin rash and sores, itching, hives, fever, painful urination
Colcrys (colchicine)
XANTHINE OXIDASE INHIBITOR

DOSAGE: tab(0.6mg)
MOA: inhibits xanthine oxidase, interferes w/ production of uric acid
INDICATION: gout
ADRs: vomiting, diarrhea, nausea
Prednisone
GLUCOCORTICOID

DOSAGE: tab(1,2.5,5,10,50mg) soln(5/5ml)
MOA: anti-inflammatory
INDICATION: asthma, PCP, MS
ADRs: difficulty sleeping, nervousness, indigestion, nausea
What is a major side effect of prednisone?
Cushing Syndrome=increased susceptibility to infections, osteoporosis, vertebral compression
one major counseling point for prednisone
don't stop taking it suddenly = lead to unpleasant withdrawal symptoms and can weaken immune system
Classes of antibiotics that cause photosensitivity
1. TCN antibiotics
2. Bactrim
which drug has an off-label use for treatment of Rosecea?
Doxycycline Hyclate
drugs indicated for treatment of UTI
1. cephalexin
2. levofloxacin
3. ciprofloxacin
4. doxycycline hyclate
5. bactrim
drugs indicated for treatment of otitis media
1. Amoxicillin
2. penicillin
3. amox/clav
4. cephalexin
5. cefdinir
6. azithromycin
drug used for malaria prophylaxis
1. doxycycline hyclate