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140 Cards in this Set

  • Front
  • Back

Tissues

Made up similar cells that function together


Similar speciality

4 types of tissue

Epithelial


Connective


Muscle


Nerve

Importance of understanding radiology

1) Wound healing & repair (gingivitis and perio)


2) Pathology that can occure

Turnover time

Time it takes cells to be completely replace


Help fight disease process in oral cavity

Epithelial tissue

Covers and lines body surfaces



Epithelial tissues protect from what

physical


chemical


microbial


dehydration


heatloss

Epithelial tissues involved in

Absorbption


Secretion


Sensory & specialized function

Epithelial derived from

Ectoderm - skin & oral region


Endoderm - respiratory & digestive


Mesoderm- urinary tract

Characteristics of Epithelial Tissue

Polyhedral Cells with little or no interstitial fluid


Rapid Turnover


Differentiate as they move to surface


Avascular


Joined by intercellular junctions

Intercellular junctions

Hemidesmosomes - non cellular surface


desmosomes - cell to cell

Nutrition for epithelial comes from

metabolites from adjoining connective tissue

Basement membrane

Between Epithelium & Connective tissue

Simple Squamous Epitheliar

flat squames -


blood & lymph vessels


heart


lung


kidney interfaces (Endothelium)



Simple cuboidal Epitheliar

Ducts of gland


like salivary

Simple Columnar epitheliar

other parts of salivary glands & IEE

Pseudostratified Epithelium

nuclei are at different levels


Really simple epi. b/c ALL cells contact basement


Nasal Cavity & Paranasal sinuses

Staratified epithelium

2 or more layers only lower layer contacts basement


Can be cuboidal, columanr, squamous, combinations


Keratinized or non keratinized

Most stratified epithelium are what shape located where

squamous


skin


oral mucosa

Rete Ridges

Extensions of epithelium into connective tissue for communication

Keratin

tough protien resistant to bacteria and friction


Epidermis of skin

Repair and turnover of EPithelium

Occurs deep and migrate superficaially


TIme it takes cell to divide and move


Time is quick b/c high level of mitosis

Buccal mucosa tunover

14 day turnover

Skin turnover

27 day

Process after injury with clot

clot triggers inflammation from WBC.


Epithelial tissue lose inter-cellular junction and migrate below clot.


Clot guides new surface.


Clot then broken down by enzymes.



Basement membrane

Thin


Acellular


Chemical based structure


Between epithelial and connective tissue

Basal Lamina

Superficial layer produced by epithelium


lamina lucid


Lamina densa

Lamina Lucid

Clear


Close to epithelium

Lamina densa

dense


Located close to connective tissue

Reticular lamina

Deeper portion of basement membrane


Collagen & Reticular fibers secreted by connective tissue

Attachment of basement membrane

Hemidesmosomes - plaque


Tonofilaments - from epithelium


Anchoring fibers - from connective

Connective Tissue

Most abundant by weight

Derived from somites


Fewer cells than epithelium'


Spaced with lots of matrix


Ability to produce own matrix and fibers


Vasucular

Connective tissue involved in

Support


Attachment


Packing


Insulation
Storage


Transport


Repair


Defense

Fibroblast

Most common


Synthesize protein and intercellular substance


Flat & elongated


Cytoplasmic process at each end


Do not enter blood

Fibroblasts produce what

fibers


intercellular substance


Large amounts of cytoplasm, mitochondria, & rough ER

Fibroblasts & Perio

Can become inactive in late perio but revert during repair

Migrated WBC

Monocyte - macrophage


Basophils - mast cells


Lymphocytes - plasma cells


Nutrophils





Protein fibers in connective tissue

Collegen


Elastic


Reticular

Collegen

in all connective tissue except blood


Type 1 found indermis tendon, bone, and teeth

Cells responsible for forming Type 1

osteoblast


odontoblasts


fibroblasts

Elastic Fibers

Micro-filaments in the protein elastin


Soft palate

Reticular fibers

Least common


In embryonic tissue


Lymph


Spleen

Connective tissue grouped according to

texture


soft


firm


rigid


fluid

Soft connective tissue

deep skin


oral mucosa


AKA Connective Tissue Proper



Firm conective

Cartilage

Rigid connective

Bone

Fluid connective

Blood and lymph

Connective tissue proper

Soft


loose dense and specialized

Loose and dense connective tissue in 2 layers forms

Connective tissue proper in deep and oral mucosa

Connective tissue proper of skin and deeper tissue

Dermis


Deep to epidermis


hypodermis - made of loose and specialized

Connective tissue proper of Oral mucosa


and deep connective tissue

lamina propria


deep connective tissue is submucosa

Loose connective tissue/ papillary layer

superficial layers of skin and lamina propria


equal parts of cells, intercellular space, fibers and fluid in loose irregular arrangement


protection/ Padding

Papillary papillae

extensions of connective tissue into epithelium for communication



Dense connective tissue/ reticular layer

Deep to loose connective tissue


In Deep Layers of lamina propria & dermis


Tightly packed for strength


Irregular arrangement



Arrangement of tendons ligaments and aponuroses

regular arrangement

Connective tissue turnover and repair

Slower than epithelial


Produce fibers and intercellular substance by fibroblasts





Injury, clot and repair of connective tissue

Clot


Inflammation


Fibroblast make immature conntective tissue Granulation tissue that appears red and bleeds easily


Replaced by scar tissue

Skin at birht

frgile & sensitive

Skin at puberty

Active


Sensitive to allergens

Skin at 20 `

deteriation

Skin at 50

Rapid deterioration


Elastic stiffens


Melanin decreases


poor healing


susceptible to inflammation, infection, and cancer

Specialized Connective tissue

Adipose


Elastic


Reticular

Adipose

tightly packed, no matrix


beneath skin, around organs & joins


oral cavity

Elastic tissue

elastic fibers give strength and elasticity


Vocal cords

Reticular tissue

delicate network


blood vessels and internal organs

CArtilage

Firm


Temporary skeleton of embryo


In free moveable joint (TMJ)


Flex from fibers in matrix


model for bone development


Avascular & no nerve


long repair process

Pericardium

tissue that surrounds cartilage

Cartilage tissue

Calls and matrix


Chondroblasts &Chondrocytes

Chaondrblast

internal to pericardium


produce matrix

Chondrocyte

mature cohndroblast


maintain matrix


becomes enclose in matrix

Lacuna

surrounds condrocyte in matrix

3 types of cartilage

Hyline


Elastic


Fibrocartilage

Hyline

most common


only collegen


embryonic skeleton & mandibular condyle

Elastic

elastic fibers & collegen


External ear


Auditory tube


Epiglottis


Larynx

Fibrocartilage

Never alone


Merges with Hyaline


TMJ


Transitional


In capsules


No pericardium

Interstitial Growth

Deep in the tissue


Mitosis of chondrocytes


Daughter cells single lacuna


Lacuna secrets matrix and expands tissue


Bone development that use cartilage as model

Appositional growth

Layered on outside from chondroblasts in pericardium


after injury or remodeling

Aging Cartilage

less celular as chondrocytes die


firm fibers or calcify loosing flex

Repair of cartilage

slow


avascular


depends on connective tissue to transform


may fill with dense connective tissuse (vascular) and become bone

Bone

Rigid Connective


protection, support, and attachment


movement. blood cell production, calcium & mineral storage


Vascular


most differentiated

Periosteum

outer bone


double layer dense connective tissue


has nerves and blood vessels

Compact bone

dense layer deep to periosteum


less soft tissue space

Cancellous bone

Spongy


tuburculae matrix, a lattice of piesces


Rings of cone shaped spicules


Osteocytes are between lamellae of trabeculae


Lamella surrounded by space that contain vascular supply

Endosteum

inner lining of bone deep to compact and cancellous bone


thinner than periosteum but same compostion

Bone marrow

innermost portion of bone


gelatinous substance


Stem cells produced to produce RBC


Lymphocytes mature



Bone tissue

matrix 50% inorganic/ minerilized calcified


organic collagen fiber and intercellular substance of matrix

Minerals of bone

HYDROXYAPATITE - inorganic for hardness


magnesium


Potassium


calcium carbonate


flouride

Osteoid

initial matrix component produced by osteoblast

Bone remodleing and repair from layer of what

Osteoblast layer always present in periosteum and external compact bone surfaces

Osteocyte

mature osteoblasts in fully calcified bone


lacuna only 1 osteocyte


no mitosis

canuliculi

canals of matrix with cytoplasmic process for communication of osteocytes

Lamella

sheets of bone matrix


embedded with osteocyte

Haversian System

organized arrangement of lamellae


with haversian canal


noted in alveolar bone

Haversian canal/ osteonic canal

soft tissue surrounded by osteons (5-20 lamella)


contains bollod vessel, nerve and connective tissue


lined by endosteum


provide nourishment

Development of bone

Ossification

2 methods of ossification

Intramembranous


Endrochondral

Intermembranous ossification

Mesenchymal cells differentiate into osteoblast and form osteoid


appositional


osteoid materialize into bone


maxilla, mandible, clavical

Endrochondral ossification

osteoid in hyaline cartilage


cartilage dies and osteoblast penatrate cartilage and form osteoid


Interstitial growth then appositional


long bones and head of mandibular condyle

Bone grows in stages

No matter the type


Immature


Secondary

Immature bone

initial bone


lamellae not distinct


Irregular collegen

Secondary Bone

replaces initial bone


distinct lamella


regular collegen arrangement

Bone repair and remodel

Dependent on adequate blood supply


Immature then secondary bone


Osteoblasts

Osteoclast

reabsorbtion


removal of bone

Localized reabsorption

specific area of bone as a result of infection or pressure


uncontrolled manner - perio


controlled - orthodontics

Generalized reabsorption

varying amounts in skeleton from endocrine activity


Can occur with a bone disorder

Arrest lines

in general reabsorption


lines from resting osteoblasts

Reversal lines

General reabsorption


scalloped lines from bone repair

Blood

Fluid connective


transport nutrients, metabolites, and gases


carried in endothelium lined blood vessels


plasma and cells

Plasma

fluid that carries plasma rotiens, blood cells, adn metabolites

Serum

fluid from plasma


NO clotting protiens

Blood cells come from

Stem cells in bone marrow


RBC


WBC


Platelets

RBC

most common


hemoglobin to transport 02 and CO2


no nucleus


no mitosis


5-6 million / microliter

Platelets

thrombocytes


clotting


250,000- 400,000/ microliter`

WBC

leukocyte from stem cells


defense against inflmmatory and immune responses


migrate


5,000- 10,000/ microliter


colorless



5 types WBC

neutrophil


lymphocyte


monocyte


eosinophil


basophil

Nutrophil

most common


1st appear at injury site


large numbers in suppuration


54-62% of WBC in total blood


short life span

Lymphocyte

25-33% WBC


B cell


T cell


NK cell



B cells

mature in bone marrow and lymphnodes


(lymphocyte)


divide during immune response to form plasma then immunoglobulins (Ig A, D, E, G, M) or blood protien

Immunoglobulins

response to anitigen or immunogen


trigger immune response

T cell

mature in thymus


(Lymphocyte)



NK cells

mature in bone marrow


1st line of defense in tumor or viral infection

Monocyte

most common in connective tissue


2-10% of WBC count


macrophage



Macrophage

arrive later at injury site


fuse together in some disease states


*in bone they are osteoclasts

Eosinophil

granulocyte


double nucleus


6%


Allergy resonse

Basophil

granulocyte


double nucleus


.5 -1 %


Hypersensitivity

Mast Cells

similar to basophils


Hypersensitivity

Muscle tissue derived from

Somites


Shorten under neural control and cause movement of soft tissue and bone



Smooth & cardiac

involuntary


Autonomic nervous system

Skeletal

Voluntary


Somatic nervous system


Striated


Bundles, facicles of myofibers

Nerve

Carry message


for muscle contraction


stimulate gland secretion


Regulate other systems (CVS)


Sensations


Neuroectoderm

Neuron

3 component


body


2 cytoplasmic processes

Nerve bundle

neural process outsie CNS within PNS

Synapse

junction between 2 neurons

Afferent

sensory


To the brain

Efferent

Away from the brain


Muscles & glands

CNS

Brain & Spine

PNS

spine and cranial nerves

Somatic

concious control

Autonomic

with out control

Sympathetic

fight-or-flight


dry mouth

Parasympathetic

rest-or-digest


saliva to aid digestion