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26 Cards in this Set
- Front
- Back
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What is oxytocin's only use
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stimulate uterine contractions to induce or reinforce labor or promote ejection of breast milk
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To induce labor, oxytocin is administered through what route
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IV
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To induce milk let-down, Oxytocin is administered through what route
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nasal spray
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T or F: Oxytocin contracts the myoepithelial cells around the mammary alveoli
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TRUE
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Although toxicities with oxytocin are uncommon, what side effects have been reported
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hypertensive crises and uterine rupture
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This drug has both antidiuretic and vasopressor effects
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Vasopressin
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How does vasopressin work in the kidney
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it binds to V2 receptor to increase water permeability and resorption in the collecting tubules
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What is the major use of vasopressin
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treat diabetes insipidus
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Where are V1 receptors found
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Vascular smooth muscle (causes constriction)
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What are the major toxicities of vasopressin
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water intoxication and hyponatremia
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This drug has minimal activity at the V1 receptor, making it largely free of pressor effects and is now preferred for diabetes insipidus and nocturnal enuresis
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desmopressin
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How is desmopressin administered
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intranasally
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What is the most active form of the thyroid hormones T3 or T4
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T3
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Bradycardia, poor resistance to cold, mental and physical slowing are all signs of this disorder
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hypothyroidism
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How can hypothyroidism present in children
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mental retardation and dwarfism
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Antibodies to thyroid peroxide are diagnostic of this disorder
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Hashimoto thyroiditis
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Secretion of TSH by anterior pituitary is stimulated by what hypothalamic hormone
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TRH
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Feedback inhibition of TRH occurs with high levels of what hormone
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Thyroid
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Hypothyroidism is diagnosed by elevation in this hormone
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TSH
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What drug treats hypothyroidism
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Levothyroxine
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Toxicity from levothyroxine shows what characteristics
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nervousness, heart palpitations, tachycardia, intolerance to heat, and unexplained weight loss
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Graves disease is a hyperthyroidism state where TSH levels are increased or decrased
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Decreased
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T or F: most pts become hypothyroid as a result of radioactive iodine 131I and require treatment with levothyroxine
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TRUE
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These two drugs inhibit thyroid hormone synthesis
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Propylthiouracil (PTU) and methimazole
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Why are PTU and methimazole not effective in treatment of thyroid storm
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b/c they're slow in onset
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What drugs are effective in thyroid storm tx
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beta blockers such as propranolol administered IV and CCB such as diltiazem in pts who suffer from severe heart failure or asthma
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