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20 Cards in this Set

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What test is used to diagnose thyroid problems?
TSH
What is the usual TSH range?
????
S/S: Hypothyroidism
Cold intolerance
Fatigue
Drowsiness
Poor Memory
Depression
Constipation
MOA: HYPOthyroid medications
T4 is converted to T3 and exerts metabolic effects through control of DNA transcription and protein synthesis
Brand: Levothyroxine
Synthroid
Levoxyl
Don't use HYPOthyroid drugs if...
Recent MI
Uncorrected adrenal insufficiency (if adrenal is the root of the cause, extra thyroid hormone won't fix the problem)
Side effects: Levothyroxine
Angina
Anxiety
Alopecia
Increased LFT
Tachycardia
Brand: Dessicated Thyroid
Armour
Thyroid
Side effects: Armour (dessicated thryoid)
Don't use if hypersensitivity to beef or pork
Same side effects as levothyroxine
Is levothyroxine T3 or T4?
T4 (it must be converted to T3 to be active)
Levothyroxine: Drug Interactions
Positive cations or binding drugs may decrease absorption (cholestyramine, aluminum containing drugs, sucralfate, kayexalate, PHT, CBZ, rifampin)
Name the T3 thyroid medication
Liothyronine
Levothyroxine: Admin
Administer on an EMPTY stomach
S/S: HYPERthyroidism
Heat intolerance
Weight loss
Insomnia
Weakness
Palpitations
Anxiety
Treatment: HYPERthyroidism
Radioactive iodine
Methimazole
Propylthiouracil
MOA: HYPERthyroid medications
inhibits synthesis of thyroid hormones by blocking oxidation of iodine in the thyroid gland
Should methiamazole or propylthiouracil be used during pregnancy or while breast feeding?
NO: Propylthiouracil is preferred in pregnancy if necessary
S/S: Polycystic ovary syndrome
Infertility
Hirsutism
Obesity
Amenorrhea
Treatment: Polycystic ovary syndrome
Insulin sensitizing agents (metformin, pioglitazone, rosiglitazone)
Combination oral contraceptives
Clomiphene citrate (up to 6 months)
Brand: Liothyronine
Cytomel