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5 Cards in this Set
- Front
- Back
What is the treatment for hypothyroidism? Which form is given if the patient is deficient in 5-deiodinase?
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T4 (Levothyroxine) given (converted to T3 in the body by 5-deiodinase)
Give T3 form (Liothyronine) if deficient in 5-deiodinase. |
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What are the two invasive options for hyperthyroidism?
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Surgical removal
Radioactive iodine |
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Why are glucocorticoids used to treat hyperthyroidism?
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Decreases TSH receptor antibody production in Grave's.
Decreases TSH production by the anterior pituitary. Slows T4 --> T3 conversion |
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How does propylthiouracil work to treat hyperthyroidism? What is the main side effect? What formulations are available? When are they used?
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Inhibits thyroid peroxidase to prevent iodination and coupling of hormone.
Blocks T4--> T3 (propylthiouracil) Side effect- liver damage (propylthiouracil) options: propylthiouracil, methimazole, carbimazole Used for Grave's and prior to thyroidectomy. |
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What are the rapid effects of iodide in the hyperthyroid patient? What occurs after a few days? What is it used to treat?
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1-2 days, inhibits iodide concentration by blocking the symporter.
7-10 days, decreased hormone synthesis and decreased release of exisiting T4/T3 Used to treat a thyrotoxic storm and as an adjuvant to thyroidectomy. |