Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
5 Cards in this Set
- Front
- Back
|
What is the treatment for hypothyroidism? Which form is given if the patient is deficient in 5-deiodinase?
|
T4 (Levothyroxine) given (converted to T3 in the body by 5-deiodinase)
Give T3 form (Liothyronine) if deficient in 5-deiodinase. |
|
|
What are the two invasive options for hyperthyroidism?
|
Surgical removal
Radioactive iodine |
|
|
Why are glucocorticoids used to treat hyperthyroidism?
|
Decreases TSH receptor antibody production in Grave's.
Decreases TSH production by the anterior pituitary. Slows T4 --> T3 conversion |
|
|
How does propylthiouracil work to treat hyperthyroidism? What is the main side effect? What formulations are available? When are they used?
|
Inhibits thyroid peroxidase to prevent iodination and coupling of hormone.
Blocks T4--> T3 (propylthiouracil) Side effect- liver damage (propylthiouracil) options: propylthiouracil, methimazole, carbimazole Used for Grave's and prior to thyroidectomy. |
|
|
What are the rapid effects of iodide in the hyperthyroid patient? What occurs after a few days? What is it used to treat?
|
1-2 days, inhibits iodide concentration by blocking the symporter.
7-10 days, decreased hormone synthesis and decreased release of exisiting T4/T3 Used to treat a thyrotoxic storm and as an adjuvant to thyroidectomy. |
