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16 Cards in this Set

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  • Back

Levothyroxine

T4 (First Choice)




Rx: Hypothyroidism, Cretinism, Hashimoto's, Myxedema Coma

Liothyronine

T3




Rx: Hypothyroidism, Cretinism, Hashimoto's, Myxedema Coma




S/E: Cardiotoxic (Increased BP/HR)

Liotrix

T4 + T3




Rx: Hypothyroidism, Cretinism, Hashimoto's, Myxedema Coma




S/E: Cardiotoxic (Increased BP/HR)

Propylthiouracil (PTU)

Rx: Hyperthyroid (Pregnancy), Graves, Toxic Adenoma, Multinodular Goiter, Thyroid Storm




MoA: Inhibit Thyroid Peroxidase (Oxidation / Coupling), and Peripheral conversion of T4 to T3




Tox: Maculopapular pruritic rash, Hepatitis, Agranulocytosis

Methimazole

Rx: Hyperthyroid (First Choice), Graves, Toxic Adenoma, Multinodular Goiter, Thyroid Storm




MoA: Inhibit Thyroid Peroxidase (Oxidation / Coupling)




Tox: Maculopapular pruritic rash, Category D Agranulocytosis

Carbimazole

Rx: Hyperthyroid, Graves, Toxic Adenoma, Multinodular Goiter




MoA: Inhibit Thyroid Peroxidase (Oxidation / Coupling)




Tox: Maculopapular pruritic rash, Category D Agranulocytosis

Perchlorate (ClO4-)

Rx: Hyperthyroid, Graves, Toxic Adenoma, Multinodular Goiter




MoA: Block Iodine Trapping




S/E: Aplastic Anemia

Pertechnetate (TcO4-)

Rx: Hyperthyroid, Graves, Toxic Adenoma, Multinodular Goiter




MoA: Block Iodine Trapping




S/E: Aplastic Anemia

Thiocyanate (SCN-)

Rx: Hyperthyroid, Graves, Toxic Adenoma, Multinodular Goiter




MoA: Block Iodine Trapping




S/E: Aplastic Anemia

Iodine (Lugol's, Na+, K+)

Rx: Hyperthyroid, Thyroid Storm, Surgery, Radiation




MoA: Inhibit hormone release, Shrink gland (Wolff-Chaikoff)




Tox: Acneiform rash, Swollen Salivary glands, Mucous Membrane Ulcers, Conjunctivitis, Rhinorrhea, Anaphylactoid reaction

Radioactive Iodine (I-131)

Rx: Hyperthyroid, Graves (First Choice), Toxic Adenoma, Multinodular Goiter




MoA: Beta radiation




S/E: Hypothyroidism (80%)




C/I: Pregnancy, Young

Metoprolol

Rx: Hyperthyroid, Graves, Toxic Adenoma, Multinodular Goiter




MoA: Adrenoceptor Blocker




S/E: Palpitations, Nervousness, Tremor

Propranolol

Rx: Hyperthyroid, Graves, Toxic Adenoma, Multinodular Goiter, Thyroid Storm




MoA: Adrenoceptor Blocker




S/E: Palpitations, Nervousness, Tremor

Atenolol

Rx: Hyperthyroid, Graves, Toxic Adenoma, Multinodular Goiter




MoA: Adrenoceptor Blocker




S/E: Palpitations, Nervousness, Tremor

Diltiazem

Rx: Thyroid Storm




MoA: Ca+ Channel Blocker

Hydrocortisone

Rx: Thyroid Storm