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22 Cards in this Set
- Front
- Back
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pyknosis
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basophilia
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kayhorrexis
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pyknotic nuclear fragmentation
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karolysis
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nuclear fading
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2 genes that can cause intrinsic apoptosis
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inc. Bax
dec. Bcl-2 |
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2 extrinsic apoptosis pathways
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Fas-L (CD95)
Natural Killer Cells (perforin, granzyme B) |
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chronic inflammation is ___ cell mediated
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mononuclear
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rolling PMNs by what endothelial proteins
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E-selectin
P-selectin |
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Tight adherence of PMNs by what endothelial protein
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ICAM-1
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Diapedesis of PMNs by what endothelial protein
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PECAM-1
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4 signal that produce PMN chemotaxis
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CILK
C5a IL-8 LTB4 Kallikrein |
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what phase of liver metabolism can cause free radical production
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I
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what vitamins are antioxidants
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A,C,E
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superoxide can be formed in large quantities after what happens
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reperfusion after anoxia (ex. thrombolytic therapy)
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7 granulomatous diseases
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tuberculosis
fungal infections sarcoidosis syphillis cat scratch fever leprosy chron's disease |
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what cytokine induces granuloma formation
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TNF-alpha (from macrophages)
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3 conditions causing dec. ESR
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sickle cell
polycythemia CHF |
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acute iron poisoning symptom
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gastric bleeding
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chronic iron poisoning syptoms
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metabolic acidosis, GI obstruction due to scarring
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what is amyloid product in:
DM2 medullary carcinoma of the thyroid alzheimers dialysis-associated |
DM2- amylin
medullary carcinoma of the thyroid- A-CAL alzheimers- beta amyloid dialysis-associated- beta2 microglobin |
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1 decreased surface protein and 2 increased surface proteins in metastatic cancer cells
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dec- cadherin
inc.- lamins, integrin receptors |
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anaplasia
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abnormal cells lacking differentiation
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differences between mature teratoma in men and women
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women- benign
men- malignant (usually in testes) |
