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74 Cards in this Set
- Front
- Back
down syndrome neoplasms
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ALL
AML |
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Xenoderma Pigmentosum neoplasms
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squamous cell carcinoma
basal cell carcinoma melanoma |
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chronic atrophic gastritis/ pernicious anemia/ postsurgical gastric remnants neoplasms
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gastric adenocarcinoma
|
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tuberous sclerosis neoplasms (3)
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astrocytoma, angiomyolipoma, cardiac rhabdomyoma
|
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actinic keratosis neoplasms
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squamous cell carcinoma
|
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Barrett's esophagus neoplasms
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Esophageal Carcinoma
|
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Plummer-Vinson syndrome (iron deficiency causing atrophic glossitis, esophageal webs, anemia) neoplasms
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squamous cell carcinoma of esophagus
|
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alcoholism, hep b, hep C neoplasms
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hepatocellular carcinoma
|
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ulcerative colitis neoplasms
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colonic adenocarcinoma
|
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paget's disease (of bone) neoplasms (2)
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2ndary osteosarcoma, fibrosarcoma
|
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Immunodeficient state neoplasms
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malignant lymphomas
|
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AIDS neoplasms (2)
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aggressive malignant non-Hodgkin's lymphomas, Kaposi's sarcoma
|
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Autoimmune disease (Hashimotos's, myasthenia gravis) neoplasms
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lymphoma
|
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acanthosis nigrans neoplasms
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visceral malignancy (stomach, lung, breast, uterus)
|
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dysplastic nevus neoplasms
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malignant melanoma
|
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radiation exposure neoplasms (2)
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papillary thyroid cancer
sarcoma |
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abl
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CML (oncogene)
|
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c-myc
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Burkitt's lymphoma (oncogene)
|
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bcl-2
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Follicular and undifferentiated lymphomas (oncogene)
|
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erb-B2 (3)
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breast, ovarian, gastric carcinomas (oncogene)
|
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ras
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colon cancer (oncogene)
|
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L-myc
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Lung tumor (oncogene)
|
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N-myc
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Neuroblastoma (oncogene)
|
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ret
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MEN types 2 and 3 (oncogene)
|
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c-kit
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gastrointestinal stromal tumor (oncogene)
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Rb (2)
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retinoblastoma, osteosarcoma (13q) (tumor suppressor)
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p53 syndrome associated
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most human cancers and Li-Fraumeni syndrome (17p) (tumor suppressor)
|
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BRCA1
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breast cancer
ovarian cancer (17q) (tumor suppressor) |
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BRCA2
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breast cancer
(13q) (tumor suppressor) |
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p16
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melanoma
(9p) (tumor suppressor) |
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APC
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colon cancer (associated with familial adenomatous polyposis)
(5q) (tumor suppressor) |
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WT1
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Wilm's Tumor (associated with WAGR complex)
(11p) |
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NF1
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Neurofibromatosis 1
(17q) (tumor suppressor) |
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NF2
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Neurofibromatosis 2
(22q) (tumor suppressor) |
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DPC
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pancreatic cancer (dpc depleted in pancreatic cancer)
(18q) (tumor suppressor) |
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DCC
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colon cancer (depleted in colon cancer)
(18q) (tumor suppressor) |
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PSA tumor marker
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prostate carcinoma (+ BPH, prostatitis)
|
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Prostatic acid phosphatase tumor marker
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prostate carcinoma
|
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CEA tumor marker
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carcinoembryonic antigen. colorectal, pancreatic, gastric, breast, thyroid medullary cancers
|
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AFP tumor marker (2)
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hepatocellular carcinoma, yolk sac tumor
|
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bHCG (3) tumor marker
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hydratiform moles, choriocarcinoma, gestational trophoblastic tumors
|
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CA-125 tumor marker
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ovarian, malignant epithelial tumors
|
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S-100 (3) tumor marker
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melanoma, neural tumors, astrocytoma
|
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Alkaline Phosphatase (3) tumor marker
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metastases to bone, Paget's disease of bone, obstructive biliary disease
|
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TRAP (tartrate-restistant acid phophatase) tumor marker
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hairy cell leukemia (TRAP the hairy animal)
|
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aflatoxins (from aspergillus)
(chemical carcinogens) |
hepatocellular carcinoma
|
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vinyl chloride
(chemical carcinogens) |
angiosarcoma
|
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CCl4
(chemical carcinogens) |
liver (centrilobular necrosis, fatty change)
|
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nitrosamines (in smoked foods)
(chemical carcinogens) |
esophagus cancer
stomach cancer |
|
cigarette smoke (4)
(chemical carcinogens) |
-esophageal cancer (squamous cell)
-lung cancer (squamous cell, small cell) -kidney (renal cell carcinoma) -bladder (transitional cell carcinoma) |
|
asbestos
(chemical carcinogens) |
mesothelioma
bronchogenic carcinoma |
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arsenic (2)
(chemical carcinogens) |
skin (squamous cell carcinoma)
liver (angiosarcoma) |
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napthelene (anilene) dyes
(chemical carcinogens) |
transitional cell bladder cancer
|
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alkylating agents
|
leukemia
|
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ACTH
(paraneoplastic syndromes) |
small cell lung carcinoma
|
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ADH
(paraneoplastic syndromes) |
small cell lung carcinoma
intracranial neoplasms |
|
PTHrp
(paraneoplastic syndromes) |
squamous cell carcinoma
renal cell carcinoma breast carcinoma |
|
Epo
(paraneoplastic syndromes) |
renal cell carcinoma
hemangioblastoma |
|
Lambert-Eaton syndrome
(paraneoplastic syndromes) |
antibodies to presynaptic Ca2+ channels at neuromuscular jxns
Thymoma small cell lung carcinoma |
|
Hyperuricemia
(paraneoplastic syndromes) |
(excess nucleic acid turnover)
Leukemia Lymphoma |
|
small cell lung carcinoma paraneoplastic syndromes
|
ACTH
ADH antibodies against CA2+ |
|
Psammoma bodies seen in (4)
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-papillary adenocarcinoma of thyroid
-serous papillary cystadenocarcinoma of ovary -meningioma -malignant mesothelioma |
|
metastasis to brain (5)
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Lot of Bad Stuff Kills Glia
Lung Breast Skin (melanoma) Kidney GI |
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metastasis to liver (5)
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Cancer Sometimes Penetrates Benign Liver
Colon Stomach Pancreas Breast Lung |
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Metastasis to bone (6)
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Boners Penetrate TiTties of Kinky Ladies
Prostate (common) Thyroid & Testes Breast (common) Lung Kidney |
|
drugs: Renal toxicity (2)
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Cisplatin, Methotrexate
|
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drugs: hepatotoxicity (3)
|
6-MP, cyclophosphamide, busulfan
|
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drugs: respiratory toxicity (4)
|
busulfan, bleomycin, procarbazine, amiodarone
|
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drugs: Cardiac toxicity (2)
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Doxorubicin, Daunorubicin
|
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drugs: neurologic toxicity (3)
|
vincristine, cisplatin, paclitaxel
|
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drugs: immunosuppressive toxicity (2)
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cyclophosphamide, methotrexate
|
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drugs: hemorrhagic cystitis toxicity
|
cyclophosphamide
|
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drugs: leukemia toxicity
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procarbazine
|
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drugs: pancreatitis toxicity
|
asparaginase
|