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5 Cards in this Set

  • Front
  • Back
thiamin structure
-pyrimidine ring
-thiazole
-sulfur containing
-phosphorylation (adding P)
thiamin sources
yeast, pork, legumes, whole or enriched grains, watermelon, spinach, green peas
thiamin digestion
-exists in free form in plants and as TDP in animal products
-intestinal phosphatases remove P prior to absorption
thiamin bioavailability
-high except when present w/ antithiamin factors
-thiaminases (enzymes that destroy thiamin; present in raw fish; certain fruits and veggies; destruction can be prevented by presence of reducing agents or heat)
-inhibitors (teas and coffee)
thiamin absorption
-free thiamin absorbed from intestine
-active transport (intakes less than 5 mg/d)
-passive transport (higher intakes)
*ethanol interferes w/ absorption (into blood)-inhibits transport of thiamin from mucosal cell across the basolateral membrane (not brush border)*