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25 Cards in this Set

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___ feedback is when any deviation from set point is returned back to set pt. Stable
Negative
____ feedback any deviation from set pt drives further from set pt. no true set pt. UNSTABLE
positive
___ systems no input needed about controlled variable for initiation. Pre-emptive strike. Anticipation prevents occurence
Feed forward system
Rapid upsweep AP(inactivation gate), labor delivery, ovulation, blood clotting-(thrombosis if no control) are types of________
positive feedback
What is the sensor?
controller?
Effector?
Controlled variable?
Thermoreceptors
hypothalamus
heat prod/heat loss
core temp
Majority of control systems in body are _______
negative feedback
THe _______potential is graded, depol of AFFERENT SENSORY neuron
Generator
_____ is needed to make an action potential
voltage gated sodium channels
Thermoreceptors are found in what three places in body and how do they work?
skin, gut, brain (pre opticof hypothalamus) change firing rate
____ use C fibers (small unmyel) are TRP-V1-4,vanilloid, Capsaicin hotpeppers. 30-45 C
Warm sensitive
_____ is the only warm receptor that is voltage gated
TRPV1 Temp increase->threshold moves closer to Vm (Vm no change)
_____ receptors use menthol,TRVPM8, Potassium leak closing or sodium opening 10-38 C
Cold sensitive
Anterior hypothalamus:
Posterior hypothalamus:
responses to heat
responses to cooling

hypo: has strong ties to ANS
Oral is ___than rectal
Skin is 2 degrees ____ than core
Core temp is lowest at____
less than
cooler
6:00 A.M.
Each thermoregulatory behavior (sweating,shivering) has a specific ______ and wont be activated until its reached
set point
Cutaneous:
Viscera:
Hypothalamus:(thermostat)
pre-optic and superoptic
environment
core and environment
core
____ is activated when cold
sympathetic
thyroxin releases (inc metab)
epi/norep rele. increases hydolysis ATP ANS adrenal m
shivering
increases food intake/behavior
hyp rel TRH to pit rel TSH to thyroid rel thyroxine to every cell
_____ activated when hot
parasympathetic
insensible water loss (not controlled (respir)
sweating (sympath cholinergic bc T and L SSL Ach = increase vasodilation to duct
___adipose only in infants hydrolysis ATP (uncouples)
brown
If cutan change but core same _____ system. to increase heat loss _______
decrease heat loss_______
feed forward
vasodilation
vasoconstriction
Catecholamines,epi/nor/aldosterone decrease sodium part of heat acclimation can lead to _______
sweat inducing
Primary secretion : sodium, Cl back to blood, cause reabsor of water very concentrated
Increase ROS:________
Low ROS_______
similar to plasma but no protein, high in water, sodium
lots water litle sodium
little water, lots sodium
Purpose goosebumps-
increase heat prod
prevent conduction
increase hunger
TSH
catecholamines from adrenals
nonshivering thermogenesis
Fever- must be driven by______
made by cytokines cant cross _____
exert effects on____, this produces ____ acts on_____ cause setpt change at _____ receptor. make ____, during___, Resolution
hypothalamus
BBB
OVLT
Prostaglandin E2
hypothalamic neurons
EP3
Tb<Tset
Tb=Tset
Tb>Tset
____ body temps less than 85F
low rate chemical rxns, can be used clinically to reduce metab and O2 demand for heart or neurosurgery
Hypothermia