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28 Cards in this Set

  • Front
  • Back
“I’m having trouble breathing.”

HPI: WF is a 55 yo man who present to the ED c/o increasing SOB. The patient states that he was well until approximately four days ago when he began experiencing SOB with minimal exertion. He also reports that his coughing has increased and that his sputum color has turned from clear to yellow.

PMH: chronic bronchitis x 10 years; hospitalized three times in the past year for acute exacerbations; HTN
FH: mother is alive and well; father is alive and also has HTN
SH: currently unemployed, previous smoker of two cigars a day x 30 years, quit 1 year gago; occasional alcohol
Meds
Ipratropium bronmide MDI 2 puffs QID
Albuterol MDI 2 puffs QID PRN
HCTZ/triamterene 25 mg/37.5 mg PO daily

Allergies NKDA
ROS: SOB with productive cough (yellow sputum), denies fever or chills
PE
Gen: paitent is a well nourished man in mild respiratory distress
VS: BP 134/82 mmHg left arm sitting, P 106 RR 24 T 36.4 C
Lungs: decreased breath sounds BL; air movement decreased markedly; inspiratory and expiratory wheezes LBL without any rales or rhonchi
Ext: Co CCE
Remainder of PE normal
Labs: Hgb 17.5 Hct 51.9% WBC 11.2 with 67% PMNs, 4% bands, 19% lymphs, 10% monos
ABG: pH 7.42, PCO2 46 PO2 61 SaO2 93% on room air
CXR: increased bronchovascular markings in the lower lung fields consistent with COPD, no effusions of infiltrates




What risk factors does this individual have the COPD?
What signs, symptosm and labs indicate acute exacerbation of COPD
What additional information is necessary to completely evaluate theis paitnt?
Which bacterial organisms are usually responsible for exacerbation fo COPD?
What the tx goals?
What tx alternatives?
Design a paln for actue exacerbation.
Describe montiorign parameters ?
“I’m having trouble breathing.”

HPI: WF is a 55 yo man who present to the ED c/o increasing SOB. The patient states that he was well until approximately four days ago when he began experiencing SOB with minimal exertion. He also reports that his coughing has increased and that his sputum color has turned from clear to yellow.

PMH: chronic bronchitis x 10 years; hospitalized three times in the past year for acute exacerbations; HTN
FH: mother is alive and well; father is alive and also has HTN
SH: currently unemployed, previous smoker of two cigars a day x 30 years, quit 1 year ago; occasional alcohol

Meds
Ipratropium bronmide MDI 2 puffs QID
Albuterol MDI 2 puffs QID PRN
HCTZ/triamterene 25 mg/37.5 mg PO daily

Allergies NKDA
ROS: SOB with productive cough (yellow sputum), denies fever or chills
PE
Gen: paitent is a well nourished man in mild respiratory distress
VS: BP 134/82 mmHg left arm sitting, P 106 RR 24 T 36.4 C
Lungs: decreased breath sounds BL; air movement decreased markedly; inspiratory and expiratory wheezes LBL without any rales or rhonchi
Ext: Co CCE
Remainder of PE normal
Labs: Hgb 17.5 Hct 51.9% WBC 11.2 with 67% PMNs, 4% bands, 19% lymphs, 10% monos
ABG: pH 7.42, PCO2 46 PO2 61 SaO2 93% on room air
CXR: increased bronchovascular markings in the lower lung fields consistent with COPD, no effusions of infiltrates

What risk factors does this individual have the COPD?
Previous smoker
What signs, symptoms and labs indicate acute exacerbation of COPD
Increased intensity of sx, h/o frequent exacerbations (hospitalized 3 x in past year), mild respiratory distress (decreased breath sounds, markedly decreased air movement, general appearance of distress, pO2 dropping and pCO2 rising suggests risk for pending respiratory failure, however, not currently in respiratory distress as the SaO2 is > 90% on room air.
What additional information is necessary to completely evaluate this patient?
Spirometry
Which bacterial organisms are usually responsible for exacerbation fo COPD?
SKIP this question. Covered on p240 of textbook. Note different microbes depending on severity of exacerbation and COPD.
What the tx goals?
Prevent respiratory failure
Treat underlying pulmonary infection

What tx alternatives?
Antibiotics
Bronchodilators
Systemic corticosteroids
Inhaled corticosteroids
Oxygen
Design a plan for acute exacerbation.
Start 30-40 mg prednisolone PO daily x 7-10 days
After complete, add ICS
Recommend pulmonary rehab
Describe monitoring parameters ?
Spirometry, SaO2, ABGs in two weeks after completion of PO steroid treatment
Symptom resolution daily
Sputum culture after antibiotic regimen complete
COPD Textbook case
A 49 y.o. man with a PMH of HTN presents to the clinic c/o SOB that began about 3-4 years ago. His sx have gradually gotten worse since then. He is now unable to walk 100 yards without have to stop and rest. He also has a daily cough that is usually productive of yellowish sputum. He smokes about 11/2 ppd and has done so x the past 30 years. He also drinks on average 6-7 beers a day. He does not have any significant occupational exposures to dust, gases, or fumes.

What info is suggestive of COPD?


What risk factors does he have for COPD?

What additional information do you need to know before creating a treatmen plan for this patient?
COPD Textbook case
A 49 y.o. man with a PMH of HTN presents to the clinic c/o SOB that began about 3-4 years ago. His sx have gradually gotten worse since then. He is now unable to walk 100 yards without have to stop and rest. He also has a daily cough that is usually productive of yellowish sputum. He smokes about 11/2 ppd and has done so x the past 30 years. He also drinks on average 6-7 beers a day. He does not have any significant occupational exposures to dust, gases, or fumes.

What info is suggestive of COPD?
SOB that is chronic (3-4 years) with evidence of progression (“gradually worse”).
Productive daily cough with yellow sputum
Smokes 1 and ½ ppd x 30 years.
[study hint: see box “Key Indicators for COPD” ]

What risk factors does he have for COPD?
Tobacco smoke

What additional information do you need to know before creating a treatment plan for this patient?
PMH: any h/o asthma, allergy, sinusitis, etc
FH
History of exacerbations or previous hospitalizations
Comorbidities (heart disease, osteoporosis, malignancies)
Impact of sx on functioning
Social and family support available
Tests:
Reversibility testing to rule out (r/o) asthma
CXR to r/o tuberculosis, pneumonia, heart failure
ABGs (only if FEV1 < 50%)
SaO2 on room air
Spirometry (FEV1, FVC, FVC/FEV1)
Alpha-1 antitrypsin (only if < 45 y.o.a. with FH of COPD)
Medication allergies
Part 2
PMH: HTN x 6 years, currently controlled
SH: works as an accountant, married with two children
FH: father with emphysema and lung cancer. There is no family h/o DMType2 or heart disease
Meds: lisinopril 40 mg PO once daily; HCTZ 25 mg PO once daily

ROS:
(-) skins rash, (-) nasal congestion, drainage; (-) chest pain, paroxysmal nocturnal dyspnea, orthopnea; (+) SOB, cough, intermittent wheezing; (-) hemoptysis; (-) heartburn, reflux sx, N/V/D, change in appetite, change in bowel habits; (-) joint pain or swelling; (-) pedal edema

PE:
VS: BP 134/82 mm Hg, P 80 bpm, RR 20 /min T 35.8 C Wt 132# Ht 64 in BMI 22.7
HEENT: EOMI; mucosal membranes are moist; no evidence of JVD; no palpably enlarged cervical lymph nodes.
Lungs: barrel-shaped chest; hyperresonant percussion noted BL; lung sounds are fairly distant, no rhonchi or crackles.
CV: RRR, normal heart sounds
ABD: soft, non-tender, no hepatomegaly
EXT: no cyanosis, edema, or finger clubbing; evidence of onychomycosis on all fingernails

PFTS
Prebronchodilator Postbronchodilator
Actual % Predicted Actual % Predicted
FVC (L) 4.4 107% 4.0 97%
FEV1 (L) 1.68 50% 1.59 47%
FEV1/FVC 39%
CXR: hyperlucency and hyperinflation of the lungs suggestive of emphysematous change


What is your assessment of this person’s COPD?

What stage of COPD?

List treatment goals for his COPD.


What nonpharmacologic and pharmacologic interventions would you recommend?
Part 2
PMH: HTN x 6 years, currently controlled
SH: works as an accountant, married with two children
FH: father with emphysema and lung cancer. There is no family h/o DMType2 or heart disease
Meds: lisinopril 40 mg PO once daily; HCTZ 25 mg PO once daily

ROS:
(-) skins rash, (-) nasal congestion, drainage; (-) chest pain, paroxysmal nocturnal dyspnea, orthopnea; (+) SOB, cough, intermittent wheezing; (-) hemoptysis; (-) heartburn, reflux sx, N/V/D, change in appetite, change in bowel habits; (-) joint pain or swelling; (-) pedal edema

PE:
VS: BP 134/82 mm Hg, P 80 bpm, RR 20 /min T 35.8 C Wt 132# Ht 64 in BMI 22.7
HEENT: EOMI; mucosal membranes are moist; no evidence of JVD; no palpably enlarged cervical lymph nodes.
Lungs: barrel-shaped chest; hyperresonant percussion noted BL; lung sounds are fairly distant, no rhonchi or crackles.
CV: RRR, normal heart sounds
ABD: soft, non-tender, no hepatomegaly
EXT: no cyanosis, edema, or finger clubbing; evidence of onychomycosis on all fingernails

PFTS
Prebronchodilator Postbronchodilator
Actual % Predicted Actual % Predicted
FVC (L) 4.4 107% 4.0 97%
FEV1 (L) 1.68 50% 1.59 47%
FEV1/FVC 39%
CXR: hyperlucency and hyperinflation of the lungs suggestive of emphysematous change


What is your assessment of this person’s COPD?
Stage III COPD with reduced exercise capacity as evidenced by unable to walk 100 yards, FEV1 < 50%, at risk for respiratory failure
What stage of COPD?
3
List treatment goals for his COPD.
Relieve symptoms
Prevent disease progression
Improve exercise tolerance
Improve health status
Prevent complications
Prevent exacerbations
Reduce mortality
Prevent or minimize side effects

What nonpharmacologic and pharmacologic interventions would you recommend?
Pulmonary rehab
Oxygen may be needed if SaO2 < 90% on room air and/or PaO2 < 60 mm Hg
Pharmacologic regimen should include:
Up-to-date influenza vaccination
SABD PRN (beta-agonist or anticholinergic)
LABD scheduled
Inhaled glucocorticosteroids (if repeated exacerbations)
What is treatment option that is worst case scenario in COPD?
Pulmectomy
Hallmark symptom of COPD?
Dyspnea
preventable and treatable disease characterized by progressive airflow limitation that is not fully reversible and abnormal inflammatory response of lung to noxious particles or gases
COPD
presence of cough and sputum production for at least 3 months in each of 2 consecutive years(not necessarily associated with airflow limitation).
Chronic Bronchitis
destruction of the alveoli; a pathological term used clinically but only describes one of several structural abnormalities present in pts with COPD.
Emphysema
List the common risk factors for developing COPD. Which one is the most commonly encountered?(4)
Tobacco smoke(most common)
Occupational dusts and chemicals
Indoor air pollution
Outdoor air pollution
Describe the key indicators when a diagnosis of COPD is being considered? Over what age are these good indicators?(4)
Age over 40 with:
1. Dyspnea: progressive, worse with exercise, persistent(daily)
2. Chronic cough: intermittent, unproductive
3. Chronic sputum production: any pattern
4. History of exposure to risk factors
Stage I -MILD
FEV1:
FEV1/FVC:
Presentation
S1
FEV1: >80%
FEV1/FVC: <70%
Presentation: May be unaware of abnormal lung function
Stage II -moderate
FEV1:
FEV1/FVC:
Presentation
S2
FEV1: 50-80%
FEV1/FVC: <70%
Presentation: Often difficulty on expiration(this is where most pts seek help)
Stage III-severe
FEV1:
FEV1/FVC:
Presentation: (3)
S3
FEV1: 30-50%
FEV1/FVC: <70%
Presentation: More SOB, reduced exercise capacity, repeated exacerbations
Stage IV Very severe
FEV1:
FEV1/FVC:
Presentation
S4
FEV1: <30%
FEV1/FVC: <70%
Presentation: FEV1 <50% + Chronic Respiratory failure
Though asthma can usually be distinguished from COPD, what symptoms makes them difficult to distinguish?
In some individuals with Chronic Respiratory symptoms and fixed airflow limitation it remains difficult to differentiate
What are the 5 A's for helping someone quit smoking?
Ask - document
Advise - Implore against
Assess -are you ready to quit
Assist - Quit plan
Arrange - Schedule follow-up
What are the general principles of managing stable COPD?(3)
-Determine disease severity
-Implement a stepwise treatment plan
-Choose treatments
At what stage of COPD would a LABD(long-acting bronchodilator be used)
SII
When would an ICS be added to COPD therapy. Under what conditions?
SIII. Repeated exacerbations