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7 Cards in this Set
- Front
- Back
cyclic regimen for woman with uterus
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Cyclic therapy:
0.3mg/d CEE or equivalent estrogen and progestin 10-14 days/month Cyclic progestin = MPA 5mg/d or norethindrone 2.5 mg/d or norgestrel 0.15mg/d |
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WHI prempro study- what was being tested?
outcomes? (3) |
CEE 0.625mg/MPA 2.5mg QD or pbo
cancer- increase in breast CHD** primary outcome- ppl thought prempro could decrease CHD but there were early instances of CHD + stroke later on fracture risk |
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WHI study
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STOPPED BECAUSE OF BREAST CANCER
ALSO INCREASED RISK OF DEMENTIA |
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ARR in WHI
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ARR for everythign in WHI was 1%
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premarin only- outcomes
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premarin only- no increase in CHD, no increase in breast cancer (improved actually)
but increase in everything else (stroke, DVT) |
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onset of action for antidepressant usage
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improvement in 1 week for venlafaxine, paroxetine, gaba
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monitoring for HRT- 6 things at baseline
then how often after d you monitor everything? |
Pelvic and breast exam, Pap smear, mammography
lipid profile, BP Unopposed estrogen = endometrial evaluation to rule out hyperplasia or CA E + P = no endometrial evaluation required BP- eveyr 2 years eveyrthing else annually |