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25 Cards in this Set

  • Front
  • Back
What happens in early phase reaction and when does it happen?
Occurs minutes after exposure.

Release:
Histamines,
PG,
Kinase,
Lurkotrienes,
Tryptase

causes:
Vasodilation
Production of Nasal secretions
Increased Vascular Premeability
What happens in late phase reaction and when does it happen?
Occurs 4-8 hours after the exposure

Nasal congection
What classifies AR to be intermittent?
<4 days per weeks
OR
<4 consecutive weeks
What classifies AR to be persistent?
>4 days per week
AND
>4 weeks
What do you use to treat Conjuctivitis Rhinitis
Oral or ophthlamic antihistamines

saline

ocular steroids
Antihistamines are H1 receptor ________
antagonists
Negative side effect of Antihistamines
Anticholinergic SE

dec secretions
difficulty urinating, Constipation
DROWSINESS
treatment of conjuctivitis rhinitis
oral or ophthalmic antihistamines

saline

ocular corticosteroids
Negative SE of Antihistamines
Anti- Ach SE
(dec secretions, difficulyt urinating, Constipation, DROWSINESS)
patient counseling for antihistamines
take 1-2 hrs before exposure

drowsiness

take with food
Dont use these antihistamines with a patient with parkinsons
Zyrtec

Xyzal
these are sympathomimetic agents
Decongestants
This combination works best for nasal congestion
Oral antihistamines and Decongestants
SE Decongestants
Systemic:
inc BR and HR
CNS Stimulation

Localized:
Burning
Sneezing

Rebound Congestion
These Allergy meds would not be good for Hypertensives
Decongestants
What are the effects of Nasal Steroids?
dec. Inflammation
Mild Vasoconstriction
Inhibition of Late phase
Patient Counseling for Nasal Steroids
avoid sneezing or blowing nose for 10 minutes

takes 2-3 weeks for peak response

protects against asthma exacerbations
This is reserved for treatment failure with other therapyies
Anticholinergic agent
(Ipratropium Nasal Spray)
This is best for patients with a strong history of severe symptoms that are unsuccessfully controlled by pharmacotherapy and avoidance
Immunotherapy
which is the only nasal corticosteroid that is listed as Preganancy Category B?
Budesonide

Rhinocort AQ
can immunotherapy be continued during pregnancy?
yes
which class of antihistamines is preferred in children?
2nd generation
Best Intranasal corticosteroids for children
mometasone (Nasonex)

Fluticasone (Flonase)

Budesonide (Rhinocort)
this is required with more persistent, severe symptoms of Allergic rhinitis in children
Intranasal Corticosteroids
This may be used in meds for SERIOUS thinorrhea
Ipatropium