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28 Cards in this Set

  • Front
  • Back
internal defense mechanism against pathogens

immune system

the immune system that is immediate, non-specific immunity, germline encoded, and has no learning process or memory

innate immune system

the immune system that has acquired specific immunity, develops throughout our life and has specific recognition and memory
adaptive immune system
What are the 3 components of the innate immune system?

first line defenses, sensor system, innate effector actions

What do the first line defenses of the innate immune system do?

blocks entry

What do the sensor systems of the innate immune system do?

detect invasion

What do the innate effector actions of the innate immune system do?
destroy invaders
these are barriers blocking entry

first line defenses

these detect when invaders breach the innate immune system

sensor systems

these work to destroy invaders

innate effector actions
What are the 4 first line defenses?

skin, mucous membranes, antimicrobial substances, normal microbiota

What first line defense is not a part of the immune system but provides considerable protection?

normal microbiota

the largest organ in our body that is difficult for microbes to penetrate, impermeable and inhospitable
skin

many layers of epithelial cells

epidermis
the outermost later of epithelial cells of the epidermis are dead and filled with what?

keratin

what are the mucous membranes of the innate immune system?

digestive, respiratory, genitourinary tracts

this removes microbes upwards towards the throat to be swallowed

mucociliary escalator

wormlike squeezing movement of intestines until secretion

peristalsis

what is the pH of our stomach?

2

what are the 3 layers of skin?

hypodermis, dermis, epidermis

a microorganism that can cause disease

pathogen

what specifically in the microorganism triggers the immune system

antigen

substances produced by our body that want to rid of microbes

antimicrobial substances

accumulates from perspiration and protects the skin

salt

this degrades peptidoglycan

lysozyme

this kills most bacteria
stomach acid
this uses H202 to form antimicrobial oxidized compounds
peroxidase enzymes

a protein that binds iron, a major element for microbes

lactoferrin