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34 Cards in this Set

  • Front
  • Back
What is the purpose of the ventricular system in the brain?
Provides us with a useful set of landmarks with which to orient ourselves in our study of the brain's anatomy
Lateral ventricles
2 c-shaped ventricles; the outermost ones
Third ventricle
on the midline, between the lateral ventricles
Cerebral aqueduct
links the 3rd and 4th ventricles
Fourth ventricle/Foramen of Luschka
midline, above the spinal cord

below the cerebral aqueduct
cerebrospinal fluid (CSF) - how is it made and what is its purpose
protects CNS and acts as a waste system

made by specialized cells lining the roofs of all the ventricles (particularly the lateral ventricles) called choroid plexus

600-700 mL made each day, chemically similar to serum/plasma
choroid plexus
specialized cells lining the roofs of the ventricles in the brain that make CSF
describe the embryological development of the brain
after the neural plate unfolds, forming the neural tube, the cephalic end of the tube becomes characterized by 3 swellings known as the three primary brain vessicles:

hindbrain (rhombencehpalon)
midbrain (mesencephalon)
forebrain (prosencephalon)
further differentiation in the primary brain vessicles results in how many distinguishable brain vessicles?
five:

mylencephalon
metencephalon

mesencephalon

diencephalon
telencephalon
What two structures compose the differentiated hindbrain?
mylencephalon

metencephalon
What is the principle structure of the mylencephalon, what is its function and in what portion of the brain is it found?
medulla - swollen anterior end of the spinal cord; crossing over of contralateral nerves occurs here; vital nuclei of cranial nerves VI through XII are here

lower part of the hindbrain
What are the two primary components of the metencephalon and in what part of the brain are they?
pons, cerebellum

upper part of the hindbrain

separated by the fourth ventricle
pons
thick, important for communication between parts of the cerebellum

implicated in Locked In syndrome (paper)

hindbrain
cerebellum
principle structure of the extrapyramidal motor system

important for proprioceptive information: muscle spindles and vestibular apparatus (inner ear)

coordinates and integrates voluntary motor movements, adjusts muscle tonus for upright posture, keeps us balanced and oriented, great temporal resolution

when you get drunk your cerebellum is fucked up!

70 billion neurons!
Where is the midbrain (mesencephalon) located?
cephalic to the pons, divided into two parts by the cerebral aquaduct
What are the two parts of the midbrain?
Tegmentum "floor" - below cerebral aqueduct

Tectum "ceiling" - above cerebral aqueduct
Tegmentum
"floor" of midbrain

includes the red nucleus and the substantia nigra; both are important nuclei in the extrapyramidal motor system (along with cerebellum)
Tectum
"ceiling" of midbrain

quadrageminal bodies: colliculi

superior colliculi - eye movement and especially eye reflexes (blinking)

inferior colliculi - some preliminary auditory processing, some sound localization, and especially the startle response to loud noise
superior colliculi
part of tectum of midbrain

eye movement and especially eye reflexes (blinking)

visual protective response - protopathic
inferior colliculi
part of tectum of midbrain

some preliminary auditory processing, some sound localization, and especially the startle response to loud noise

other animals have more processing in colliculi; this is protopathic for humans
brainstem reticular formation
part of the midbrain; network of neurons

ascending reticular activating system (ARAS)
Where's the lesion?

altered level of consciousness
brain stem lesion or dysfunction of both cerebral hemispheres
dysarthria (difficulty pronouncing words)

dysphagia (difficulty swallowing)

Where's the lesion?
lesion in the brainstem or cerebellum
Where's the lesion?

facial weakness ipsilateral to body weakness
lesion in the high pons or above
Where is the midbrain (mesencephalon) located?
cephalic to the pons, divided into two parts by the cerebral aquaduct
What are the two parts of the midbrain?
Tegmentum "floor" - below cerebral aqueduct

Tectum "ceiling" - above cerebral aqueduct
Tegmentum
"floor" of midbrain

includes the red nucleus and the substantia nigra; both are important nuclei in the extrapyramidal motor system (along with cerebellum)
Tectum
"ceiling" of midbrain

quadrageminal bodies: colliculi

superior colliculi - eye movement and especially eye reflexes (blinking)

inferior colliculi - some preliminary auditory processing, some sound localization, and especially the startle response to loud noise
superior colliculi
part of tectum of midbrain

eye movement and especially eye reflexes (blinking)

visual protective response - protopathic
inferior colliculi
part of tectum of midbrain

some preliminary auditory processing, some sound localization, and especially the startle response to loud noise

other animals have more processing in colliculi; this is protopathic for humans
brainstem reticular formation
part of the midbrain; network of neurons

ascending reticular activating system (ARAS)
Where's the lesion?

altered level of consciousness
brain stem lesion or dysfunction of both cerebral hemispheres
dysarthria (difficulty pronouncing words)

dysphagia (difficulty swallowing)

Where's the lesion?
lesion in the brainstem or cerebellum
Where's the lesion?

facial weakness ipsilateral to body weakness
lesion in the high pons or above