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10 Cards in this Set
- Front
- Back
Hydatiform mole - clinical aspects
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preeclampsia in the 1st trimester, elevated HCG (>100,000 mlU/ml), uterus "larger than dates", bleeding
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Sacrococcygeal teratoma
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remnants of the primitive streak (normally degenerates and disappears); contains various tissue types; more common in girls; becomes malignant in infancy, remove by 6 months of age
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Chordoma
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tumor arising from remnants of the notochord; intracranial or sacral region; men over 50 yo; may be either benign or malignant
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Caudal dysplasia (sirenomelia)
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due to abnormal gastrulation -> migration of the mesoderm is disturbed; constellation of syndromes from minor lesions of the lower vertebrate to fusion of the lower limbs (mermaid); associated with various cranial abnormalities (VATER, VACTERL)
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VATER syndrome
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Vertebral defects - Anal Atresia - Tracheoesophageal fistula - Renal defects
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VACTERL syndrome
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VATER syndrome + Cardiovascular defects - upper Limb defects
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Oligohydramnios
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low volume of amniotic fluid (<400 ml in late pregnancy); inability of the fetus to excrete urine due to renal agenesis, results from Potter's syndrome, etc; hypoplastic lungs due to increased pressure on the fetal thorax
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Polyhydramnios
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high volume of amniotic fluid (>2000 ml in late pregnancy); inability of the fetus to swallow due to anencephaly or esophageal atresia; associated with maternal diabetes
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Amniotic band syndrome
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bands of amniotic membrane encircle and constrict parts of the fetus causing limb amputations and craniofacial abnormalities
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Elevated AFP levels
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neural tube defects (spina bifida, anencephaly), omphalocele (allows fetal serum to leak into the amniotic fluid), esophageal and duodenal atresia (interfere with fetal swallowing)
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