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10 Cards in this Set

  • Front
  • Back
Hydatiform mole - clinical aspects
preeclampsia in the 1st trimester, elevated HCG (>100,000 mlU/ml), uterus "larger than dates", bleeding
Sacrococcygeal teratoma
remnants of the primitive streak (normally degenerates and disappears); contains various tissue types; more common in girls; becomes malignant in infancy, remove by 6 months of age
Chordoma
tumor arising from remnants of the notochord; intracranial or sacral region; men over 50 yo; may be either benign or malignant
Caudal dysplasia (sirenomelia)
due to abnormal gastrulation -> migration of the mesoderm is disturbed; constellation of syndromes from minor lesions of the lower vertebrate to fusion of the lower limbs (mermaid); associated with various cranial abnormalities (VATER, VACTERL)
VATER syndrome
Vertebral defects - Anal Atresia - Tracheoesophageal fistula - Renal defects
VACTERL syndrome
VATER syndrome + Cardiovascular defects - upper Limb defects
Oligohydramnios
low volume of amniotic fluid (<400 ml in late pregnancy); inability of the fetus to excrete urine due to renal agenesis, results from Potter's syndrome, etc; hypoplastic lungs due to increased pressure on the fetal thorax
Polyhydramnios
high volume of amniotic fluid (>2000 ml in late pregnancy); inability of the fetus to swallow due to anencephaly or esophageal atresia; associated with maternal diabetes
Amniotic band syndrome
bands of amniotic membrane encircle and constrict parts of the fetus causing limb amputations and craniofacial abnormalities
Elevated AFP levels
neural tube defects (spina bifida, anencephaly), omphalocele (allows fetal serum to leak into the amniotic fluid), esophageal and duodenal atresia (interfere with fetal swallowing)