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6 Cards in this Set
- Front
- Back
Seminoma
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Path: large, uniform cells rather organized; Syncytiotrophoblasts seen in 10% (Corresponds with 10% HCG)
Spermatocytic: older men, usually pure (no concern for mixed) orch and observe -Most common germ cell tumor; REQUIRES normal AFP is "pure" dx. - RADIOSENSITIVE |
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Embryonal
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may secrete both AFP & HCG
histo path: WTF? necrosis and hemorrhage |
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Yolk Sac
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may secrete both AFP & HCG
infants and kids Schiller-Duvall bodies on path often mets hematogenously |
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Chorio
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Syncytiotrophoblasts & Cytotrophoblasts
NEVER secretes AFP & ALWAYS secretes HCG often mets hematogenously can have small testis primary with lots of mets (even wierd places like spleen) worst prognosis of all |
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Teratoma
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"more than one germ layer in different stages of development" GI tissue, lung,bone,cartilage,squamous,neural tissue
SHOULDN'T SECRETE AFP OR HCG RESISTANT TO CHEMO/ RADS, REQUIRES SURGERY |
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Leydig Cell Tumors
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Rienke Crystals (cigar shaped)
produce testosterone & 17OH ketosteroids p/w gynecomastia, low libido, impotence |