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28 Cards in this Set

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EOL OPIOID
1. morphine sulfate

*dyspnea
*dilates pulmonary BV & reduces congestion
*anxiety from air hunger
*lower dose than for pain
*given before activity
*via IV
*Narcan is antedote
EOL ANTICHOLINERGICS
1. Atropine ophthalmic solution o/sl
2. Hyoscyamine (Levsin)--oral/sublin
3. Scopolamine--transderm

*dries up secretions that cause death rattle
*used for dyspnea
*position pt on side with towel
*no sunctioning
*retention and dryness are SE
EOL SEDATIVES
*promote relaxation of pt
*dyspnea
*benzos--pams
EOL CORTICOSTEROIDS
1. Prednisone (deltasone)

*used for bronchospasms and inflammation in and outside of lung
*used for dyspnea
EOL DIURETIC
1. Furosemide (Lasik)

*used in dyspnea
*for fluid overload, crackles, edema to reduce congestion
*preferred for heart failure & pulmonary edema
*given iv, subq, IM
EOL ANTIBIOTICS
*used for respiratory infection
*dyspnea
*considered for comfort measures
EOL ANTIEMETICS
1. Prochlorperazine (Compazine)
2. Dexamethasone (Decadron)
3. Metoclopramide (Reglan)

*if n/v is caused by constipation, an enema is used
*manage odors that can cause nausea and keep room at an appropriate temp
*combined in rectal suppository
*uremia, hypercalcemia, urinary retention
EOL ANTIPSYCHOTICS
1. Haloperidol (Haldol, Peridol)

*nosy, agitated delirium not caused by other drugs, pain, constipation
*don't give more than one antipsychotic
*lorazepam can also be given for mild agitation and restlessness
*music therapy and aroma therapy
*treat underlying cause
Nonpharmacologic for dyspnea
*circulate cool air
*wet cloth to face
*position bed upward to increase chest expansion
*deep breathing and imagery
*possible Foley catheter
EOL BENZODIAZEPINES
1. Lorazepam (Ativan)
2. Diazepam (Valium)
3. Midazolam (Versed) sedation

*given if morphine isn't cutting it
*calms fear and anxiety
*sublingual and rectal
*EOL seizures
EOL BARBITURATES
1. Phenobarbital

*second choice for seizures after benzos
CNS STIMULANTS
(AMPHETAMINE)
1. Amphetamine sulfate (Adderall)
*adhd in older people
*minimal dose
2. Dextroamphetamine sulfate
*WT loss and narcolepsy
*can cause aggression
*can cause sudden death
----amphetamine

3. Methylphenidate HCL (Ritalin)
*ADHD. given 2x/day before meals
*caffeine may increase effects
*don't give with depression
*doesn't disrupt sleep
4. Dexmethylphenidate (Focalin)
----amphetamine like
*increase attention span
*narcolepsy

*stimulate release of norepi & dopamine
*cause euphoria and alertness
*se: sleeplessness, tremors, irritability, incr heart rate, incr blood pressure, palpitations, hypertension, diarrhea, anorexia
*for narcolepsy and ADHD
*don't take at night due to causing insomnia
*avoid alcohol, taper off drug
*limit caffeine intake
*sugarless gum
*nursing mothers should avoid
*monitor WT and ht in kids
CNS STIMULANTS
ANOREXIANTS
1. Benzphetamine HCL
--avoid during preg, potential for abuse
2. Phentermine HCL
--taken in morning for appetite suppression

*appetite suppressants for short term use under 12 weeks
*phenylpropanololamine was removed from market due to hemorrhagic stroke in women
*not for children under 12
CNS STIMULANT
LIPASE INHIBITORS
*drug of choice for WT loss
*decrease GI absorption of fats
*excreted in feces
*SE: oily spotting, wet flatus, HA, N/V, hypoglycemia
CNS STIMULANT
ANALEPTICS
1. caffeine citrate
*incr heart rate and BP
*restore mental alertness
2. theophylline

*neonatal apnea
*affect brainstem, cerebral cortex, spinal
*stimulate respiration
*SE: nervous, restless, tremors, insomnia, palpitations, incr urine, N/D, ringing in ear
*more than 300 mg affects CNS and heart
*half life of caffeine is 5 hrs
RESPIRATORY STIMULANT
1. Doxapram HCL
*treats respiratory distress caused by OD, COPD, post anesthesia
*not for neonatal
*can increase blood pressure
CNS DEPRESSANTS
Side Effects
*SE of sedative hypnotics:
-hangover= residual drowsiness
-REM rebound= vivid dreams and nightmares
-dependance
-tolerance
-excessive depression
-resp depression
-hypersensitivity=skin rxns
CNS DEPRESSANTS
BARBITURATES
1. Pentobarbital sodium
*for those who have trouble falling asleep
*short acting
*used for preoperative
*can cause suicidal ideation

2. Butabarbital sodium
*intermediate
*relieve anxiety and staying asleep insomnia
*avoid using alcohol because cns depressant
*can cause abnormal thinking

3. Mephobarbital
*long acting
*used with seizures
*monitor for respiratory distress

thiopental sodium
*ultra short acting for general anesthesia

--restricted to 2 weeks or less to reduce tolerance and se
CNS DEPRESSANTS
BENZODIAZEPINES
minor tranquilizer that induces sleep

1. Alprazolam (Xanax)
*can cause resp depression, suicidal ideation, not for older adults
*not used with alcohol and certain abx
*increases digoxin levels
*grapefruit increase levels, green tea decreases effects
*SE: lethargy, drowsy, dizzy, ha, constipation, depression
*used for insomnia
*not used longer than 6 wk

2. Lorazepam ( Ativan )
*insomnia, preop sedative, anxiety

3. Diazepam ( Valium )

-rapidly metabolized in liver to active
-highly protein bound and more free drug when combined with other highly protein bound drug which increase adverse effects
CNS DEPRESSANTS
NON BENZODIAZEPINES
1. Zolpidem tartrate
*short term for insomnia, less than 10 days
*decrease dose in older adults
*foods decrease absorption, don't take with alcohol
*SE: HA, hangover, dizzy, n/v, anxiety, depression
*tolerance and dependance
*hypotension, suicide, dysrhythmia
*avoid antidepressants, psychotic, narcotic can cause severe resp depression
*take before bed, urinate prior
BENZODIAZEPINE ANTAGONIST
1. Flumazenil (Romazicon)
ANESTHETICS
1. Halothane
*inhalation liquid
*rapid induction time
*highly potent, could decrease BP
*not used in pregnancy

2. Nitrous oxide
*inhalation gas
*very rapid induction time
*rapid recovery, given with oxygen, low potency

3. thiopental sodium
* IV barbiturate
*rapid induction for general surgery
*short duration of action
*keep pt warm during
*can depress resp center, have ventilator assistance

4. Procaine HCL (Novacain)
*ester, nerve block, epidural, spinal
*dentistry
*short acting

5. Bupivacaine
*long acting
*peripheral nerve block, epidural
*amide
ANTICONVULSANTS
-types of seizures: grand mal, petit mal, psychomotor
-drugs stabilize nerve cell membranes and suppress abnormal electric impulses
-CNS depressants
-taken throughout life
-hydantoins are highly protein bound and compete with anticoagulant and aspirins causing an increase in their activity
-gingko decreases phenytoin
-don't stop taking abruptly
-take with food
-avoid alcohol
ANTICONVULSANTS
1. Phenytoin (Dilantin)
*avoid antacids for gastric distress
*no warfarin or gingko
*decreases absorption of folic acid, calcium, vit d
*caution with: preg, bradycardia, hypotension, hypoglycemia, suicidal, lupus
*slowly absorbed
*prevents grand mal and partial
*SE: HA, dizzy, confusion, sluggish, slurred speech, rash, n/v, hypotension, discoloration of urine
*adverse: leukopenia, hepatitis, depression
*make sure pt is getting adequate nutrients
ANTICONVULSANTS
2. Phenobarbital
*seizures, long acting barbiturate
*grand mal, partial, epilepticus
*used with phenytoin
*high dose in adults cause coma and resp depression. can be fatal
*causes confusion, depression, irritability in older adults and children
*AE: suicidal ideation
*can cause dependence
ANTICONVULSANTSno
3. Fosphenytoin
*grand mal, epilepticus
*decreases sodium and calcium ion influx
*converts to phenytoin
*dilute

4. clonazepam
*used in absence seizures

5. Carbamazepine
*grand mal, partial
*for seizures that don't respond to other meds
*treats bipolar disorder
*don't crush or chew sustained release

6. Lamotrigine
*grand mal, partial
*blocks sodium influx
*discontinue use if rash presents to prevent Stevens Johnson with valproic acid
*given with other anticonvulsants

7.magnesium sulfate
*for seizures caused by preeclampsia and eclampsia
*nasal congestion
*calcium gluconate
*reduces cerebral palsy
PARKINSON
1. carbidopa-levodopa
*decrease symptoms of Parkinson
*initial drug for severe so
*give before meals
*can cause dyskinesia
*less expensive
*increases dopamine
*taken by all patients at some point
*SE: N/V, dark urine, HA, dysphagia, fatigue, bitter taste
*AR: suicidal, hallucination, jerkong, hypotension, thrombocytopenia

2. amantadine
*first used for flu, decrease symptoms. antiviral
*treats drug induced
*less SE than anticholinergic
*used early to delay use of levodopa

3. selegiline hcl
*inhibits dopamine from getting broken down
*MAOIs
*used as early treatment
*decreases freezing
*avoid tyramine in cheese and cured foods
*avoid red wine and beer for 14 days

--high fiber and fluid intake to prevent constipation
-Take drug holiday or change dosage
ALZHEIMERS
1. rivastigmine
*achesterase inhibitor
*don't use with tobacco because it increases clearance
*increases effect of theophylline
*food decreases absorption
*improves memory loss
*SE: N/V/D, constipation, dizzy, depression, dry mouth, dehydration
*AR: seizures, brady, cataract, mi, Stevens Johnson, suicidal

2. donepezil
*for mild to moderate alzheimers