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115 Cards in this Set

  • Front
  • Back
How much of the brain is buried due to convolutions?
2/3
What is the surface area of the brain?
2.5 sq. ft.
Who has the most convoluted brains?
humans
What is the prominent cell type of the cerebral cortex?
pyramidal cells - all excitatory
T/F all pyramidal cells of the cerebral cortex are excitatory.
True
Where does the major output leave from the cerebral cortex layers?
layer 5 motor cortex (4)
Where does the major input come in? what cerebral cortex level?
layer 4 - primary sensory (3,1,2)
How many layers are in the neocortex?
6
How many layers are in the archicortex?
3 layers - in hippocampus, and limbic lobe and in cerebellum
Where do you find the opercular, traingular and orbital area?
in the frontal lobe
What lobe contains the upramarginal and angular areas?
parietal lobe
What lobe contains the cuneus and lingual areas.
occipital
what is an ancient surgical procedure of operating on the skull by scraping, chiseling or cutting of bone
trephanation
DId people survive trephanation?
some, yevidence of healing
Why did ancient people use trephanation?
TBI, psychiatric disorders, relition
Where did trephanation usually take place? (on skull)
frontal and upper parietal areas
_________ is the study of the mind and character based on the shape of thy skull
phrenology
In phrenology bumps and depression in the skull correlated with ____.
function
In phrenology, bumps indication _______ gyrus and depressions indicated ______ gyrus
well-developed and under-developed
There were ______ faculties identified in phrenology.
27
The first 19 faculties are common to ____- and ______; the final eight faculties are specific to _____.
men and animals, human
What are the final eight faculties of phrenology?
comparative sagacity, metphysics, senseof satire, sense of witticism, poetical talent, kindness; venevolence; gentleness; cpmassion; sensitiviy; moral sense; the faculty to imitate; the mimick; the organ of religion, the firmness of purpose; constancy; perseverence; obstinacy
Who was the discoverer of phrenology?
Franz Joseph Gall
What did Pierre Paul broca discover?
Broca's areas: he described area that when damaged, speech adn written word could be comprehended, but grammatically - correct speech and writing was not possible.
Where are Broca's areas found?
Broadmann's areas 44,45
Where in the brain is broca's area found?
on the left hemisphere in the frontal lobe -
When broca's area was lesioned in would result in _______ aphasia
motor/expressive
When you have motor aphasia can you comprehend?
written words and speech
When trying to speak what would it sound like when someone had wernickes's aphasia?
word salad - nothing was grammatically correct or made sense
What did Karl Wernicke discover?
Wernicke's area: aphasia that involved a distrubanc in the comprehension of speech, no the execution of speech
What area's are damaged when lesioning Wernicke's area?
supramarginal and angular gyri of parietal lobe
Wernicke's area converts ____ and _____-words into and ________ 'code'
written and spoken auditory
What area is damaged when someone has sensory or receptive aphasia
Wernicke's area
When have Wernicke's aphasia: speech is _______- (possible/impossible) but ______ (can/cannot) comprehend familiar written and spoken language.
possible, cannot
Broca's area is speech __________. whereas Wernicke's area is speech _______.
(understanding or formation?)
formation, understanding
When you babble incessantly you have _______ aphasia
Sensory/receptive, or Wernicke's
When you lesion the path connecting the Broca's area and Wernicke's area what kind of aphasia do you have?
Conductive aphasia
When you cannot repeat words/phrases or substitute words or change order what aphasia is being expressed?
Conductive aphasia
Who is responsible for documenting phineas gage case?
John Harlow
Phineas Gage had an iron rod pierce his skull, what lobe was damaged?
frontal
In the documenting of Gage's lesion, Harlow noticed a particular change in personality from ____- to _______.
personality change, from:
well-balanced
smart
capable
affable
to:
fitful
impatient
obstinate
profane
Harlow discovered the importance of the frontal lobe in _________ because of phineas gage.
documents frontal lobe’s importance in personality, emotional expression and behavior
The prefrontal association cortex connects to the _____ _____ nucleus of thalamus.
dorsal medial
Prefrontal association cortex is impt. in ?
planning for volunatry activiy, decision making, personality traits
T/F the prefrontal assocation cortex is related to the limbic system (emotion)
true
Where does concentration, reasoning, spontaneity, social norms occur? which lobe? and what area?
frontal lobe, in prefrontal association cortex
What did Brodmann do in 1909?
classified the cerebral cortex into 52 areas based on cytoarchitecture.
Broadmann surmised that each area was functionally __________ .(distinct, the same)
distinct - as different area had different function
Today we have now realized that brodmann's areas _______.
are not as distnict as brodmann thought, and many more function areas than originally thought.
If you lesion the Supplementary motar area (8,6) what will you see?
akinetic mutism,
What is akinetic mutism?
They dont' speak or move - the area damaged is normally responsible for plannign and programming movement (speech and body parts)
What area is on the inner surface - not visible and is responsible for programming of complex movements?
supplementary motor area
What is lesioned if a general paucity of spontaneous movement and speech?
Supplementary motor area
If you lesion the primary motor cortex, what defiicit will you see?
Dyskinesia (execution of movements)
If you lesion the primary visual cortex what will occur?
CONTRALATERAL - homonymous hemianopsia - loss of entire visual field
What will occur if you damage the frontal eye fields?
IPSILATERAL deviation - lesion impairs volunatry aversive eye movements.
Where is the FEF located?
deep to middle frontal gyrus - responsible for conjugate eye movements.
What happens when FEF is normally stimulated?
causes contralateral eye to deviate to side of stimulation
What is so special about Wilder Penfield?
He discovered the motor/sensory homunculus - studied cortex of conscious pateints during brain surgery for epilepsy.
T/F penfield stimulated parts of the cortex during brain surgery
Treu
What are some techniques to study the cortex?
ablations - damage and see
EEG - evoked potentials
Neuroradiological techniques
Metabolism -- Blood Flow, PET, Beam
Neuropsychological Assessment
what is an impairment of ability to execute a skilled motor act even though now motor paralysis?
apraxia
_____ apraxia is when loss of ability to proper use of an object due to lack of perception of it's purpose
sensory
_____ is failure or inability to recognize the importance of sensory impressions.
agnosia
___________-agnosia is an inability to recognize the significance of sounds.
auditory
_____- agnosia is the when the words are seen but not recognized.
visual
________ is suppression of vision in one eye
anopsia
___-- absence of the sense of taste
ageusia
_________ absence of the sense of smell
anosmia
loss of the ability to write
agraphia
inability to remember the names of objects
anomia
visual aphasia or word blindness
alexia
failure in the formulation of speech event though comprehension of language is normal
expressive aphasia
inability to read music
musical alexia
impairment of ability to comprehend written language
dyslexia
disturbance or loss of ability to comprehend, elaborate, or express speech concepts
aphasia
what connects various lobes in the SAME hemispher together: cortical connections or:
association fibers
Name the association fibers of teh brain.
Superior occipitofrontal
Superior longitudinal fasciculus
Uncinate
inferior occipitofrontal
inferior longitudinal fasciculus
If you damage a fasciculus (association fiber) in the brain what is teh result?
change in cognitive status
What connects the front with the temporal lobe?
uncinate
What connects the temporal lobes
anterior commissure
What connects the frontal and parietal and occipital lobes (INTERHEMISPHERIC)
corpus callosum
What connects gyri?
arcuate fibers
What runs along the corpus callosum and connects the limbic lobes -
cingulum
How many neurons are in the cortex?
20-23 Billion
What are the parts of the corpus callossum?
rostrom genu, body, splenium
How many synpases are in the brain
1.5 quadrillion
What area is primary motor?
4
What area do you visualize
39
Where are the language areas
40,39,19
What B area do you find deja vue?
20,21 Deja Vue
What B area is Broca's area?
Broca’s Area 44, 45(dominant hemisphere) - left
Motor Speech
3,1,2 Primary Sensory Lesion-
sensory neglect of contralateral body.
Lesion: 5,7
lose quality of sensation
What is area 22, and what happens if you lesion it?
Weineke’s area- lesion hear words but
can’t speak word!
What area is 5,7 what if you lesion it?
Sup Parietal
Primary association
Get info from primary sensory and put
Meaning to it (cold vs hot, rough vs smooth
Lesion: Tactile Agnosia!
What is area 41, 42
41,42 pri auditory Transverse gyrus of Heshel
Lesion area 6:
Apraxia
inability to accomplish a
given movement! NO muscle weakness or impairment!
What is area 18,19 responsible for?
19,18 Visual Association - Objects appear
lesion – physic blindness. Agnosia (visual) cannot
recognize object but know it with other senses
What is non-fluent aphasia
44,45 Broca’s non fluent aphasia: Understand but can’t speak
What is area 17 responsible for?
Primary visual lesion- cortical blindness
What does the cingulate and entorhinal cortex do?
Cortex- Cingulate- entorhinal-hippocampus
Learning and memory
What % or R handers have dominant R hemisphere?
90-95% of right handed people
have dominant left hemisphere
Stereognosis:
Figuring out the shape of an
object or direction and speed
of the stimulus
Drawing, music, spatial perception
R hemisphere
Calculation and language
is on L hemisphere
T/F Most left-handed people also have
Dominant left hemisphere, but more
Likely to have a dominant right
Than right handed persons.
true
which hemisphere has speech and writing?
Left
What hemisphere is non-dominant and considered "artsy"
R
What artery runs along the ventral surface of the brainstem?
basilar
Stroke here
ACA =
lower leg, foot contralateral
Stroke here MCA =
upper body contralateral
he anterior cerebral arteries (ACA) are a pair of arteries on human anatomy that the supplies oxygen to most .
medial portions of frontal lobes and superior medial parietal lobes
The posterior cerebral artery (PCA) is one of a pair of blood vessels that supplies oxygenated blood to the .
posterior aspect of the brain (occipital lobe) in human anatomy]
The middle cerebral artery (MCA) is one of the three major paired arteries that supplies blood to the _________. The MCA arises from the internal carotid and continues into the lateral sulcus where it then branches and projects to many parts of the _____________. It also supplies blood to the anterior __________ and the insular cortices.
cerebrum, lateral cerebral cortex,temporal lobes