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115 Cards in this Set
- Front
- Back
How much of the brain is buried due to convolutions?
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2/3
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What is the surface area of the brain?
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2.5 sq. ft.
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Who has the most convoluted brains?
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humans
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What is the prominent cell type of the cerebral cortex?
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pyramidal cells - all excitatory
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T/F all pyramidal cells of the cerebral cortex are excitatory.
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True
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Where does the major output leave from the cerebral cortex layers?
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layer 5 motor cortex (4)
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Where does the major input come in? what cerebral cortex level?
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layer 4 - primary sensory (3,1,2)
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How many layers are in the neocortex?
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6
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How many layers are in the archicortex?
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3 layers - in hippocampus, and limbic lobe and in cerebellum
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Where do you find the opercular, traingular and orbital area?
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in the frontal lobe
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What lobe contains the upramarginal and angular areas?
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parietal lobe
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What lobe contains the cuneus and lingual areas.
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occipital
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what is an ancient surgical procedure of operating on the skull by scraping, chiseling or cutting of bone
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trephanation
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DId people survive trephanation?
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some, yevidence of healing
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Why did ancient people use trephanation?
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TBI, psychiatric disorders, relition
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Where did trephanation usually take place? (on skull)
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frontal and upper parietal areas
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_________ is the study of the mind and character based on the shape of thy skull
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phrenology
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In phrenology bumps and depression in the skull correlated with ____.
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function
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In phrenology, bumps indication _______ gyrus and depressions indicated ______ gyrus
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well-developed and under-developed
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There were ______ faculties identified in phrenology.
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27
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The first 19 faculties are common to ____- and ______; the final eight faculties are specific to _____.
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men and animals, human
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What are the final eight faculties of phrenology?
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comparative sagacity, metphysics, senseof satire, sense of witticism, poetical talent, kindness; venevolence; gentleness; cpmassion; sensitiviy; moral sense; the faculty to imitate; the mimick; the organ of religion, the firmness of purpose; constancy; perseverence; obstinacy
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Who was the discoverer of phrenology?
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Franz Joseph Gall
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What did Pierre Paul broca discover?
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Broca's areas: he described area that when damaged, speech adn written word could be comprehended, but grammatically - correct speech and writing was not possible.
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Where are Broca's areas found?
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Broadmann's areas 44,45
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Where in the brain is broca's area found?
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on the left hemisphere in the frontal lobe -
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When broca's area was lesioned in would result in _______ aphasia
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motor/expressive
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When you have motor aphasia can you comprehend?
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written words and speech
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When trying to speak what would it sound like when someone had wernickes's aphasia?
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word salad - nothing was grammatically correct or made sense
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What did Karl Wernicke discover?
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Wernicke's area: aphasia that involved a distrubanc in the comprehension of speech, no the execution of speech
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What area's are damaged when lesioning Wernicke's area?
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supramarginal and angular gyri of parietal lobe
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Wernicke's area converts ____ and _____-words into and ________ 'code'
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written and spoken auditory
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What area is damaged when someone has sensory or receptive aphasia
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Wernicke's area
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When have Wernicke's aphasia: speech is _______- (possible/impossible) but ______ (can/cannot) comprehend familiar written and spoken language.
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possible, cannot
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Broca's area is speech __________. whereas Wernicke's area is speech _______.
(understanding or formation?) |
formation, understanding
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When you babble incessantly you have _______ aphasia
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Sensory/receptive, or Wernicke's
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When you lesion the path connecting the Broca's area and Wernicke's area what kind of aphasia do you have?
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Conductive aphasia
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When you cannot repeat words/phrases or substitute words or change order what aphasia is being expressed?
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Conductive aphasia
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Who is responsible for documenting phineas gage case?
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John Harlow
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Phineas Gage had an iron rod pierce his skull, what lobe was damaged?
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frontal
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In the documenting of Gage's lesion, Harlow noticed a particular change in personality from ____- to _______.
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personality change, from:
well-balanced smart capable affable to: fitful impatient obstinate profane |
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Harlow discovered the importance of the frontal lobe in _________ because of phineas gage.
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documents frontal lobe’s importance in personality, emotional expression and behavior
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The prefrontal association cortex connects to the _____ _____ nucleus of thalamus.
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dorsal medial
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Prefrontal association cortex is impt. in ?
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planning for volunatry activiy, decision making, personality traits
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T/F the prefrontal assocation cortex is related to the limbic system (emotion)
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true
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Where does concentration, reasoning, spontaneity, social norms occur? which lobe? and what area?
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frontal lobe, in prefrontal association cortex
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What did Brodmann do in 1909?
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classified the cerebral cortex into 52 areas based on cytoarchitecture.
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Broadmann surmised that each area was functionally __________ .(distinct, the same)
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distinct - as different area had different function
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Today we have now realized that brodmann's areas _______.
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are not as distnict as brodmann thought, and many more function areas than originally thought.
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If you lesion the Supplementary motar area (8,6) what will you see?
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akinetic mutism,
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What is akinetic mutism?
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They dont' speak or move - the area damaged is normally responsible for plannign and programming movement (speech and body parts)
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What area is on the inner surface - not visible and is responsible for programming of complex movements?
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supplementary motor area
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What is lesioned if a general paucity of spontaneous movement and speech?
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Supplementary motor area
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If you lesion the primary motor cortex, what defiicit will you see?
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Dyskinesia (execution of movements)
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If you lesion the primary visual cortex what will occur?
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CONTRALATERAL - homonymous hemianopsia - loss of entire visual field
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What will occur if you damage the frontal eye fields?
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IPSILATERAL deviation - lesion impairs volunatry aversive eye movements.
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Where is the FEF located?
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deep to middle frontal gyrus - responsible for conjugate eye movements.
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What happens when FEF is normally stimulated?
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causes contralateral eye to deviate to side of stimulation
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What is so special about Wilder Penfield?
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He discovered the motor/sensory homunculus - studied cortex of conscious pateints during brain surgery for epilepsy.
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T/F penfield stimulated parts of the cortex during brain surgery
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Treu
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What are some techniques to study the cortex?
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ablations - damage and see
EEG - evoked potentials Neuroradiological techniques Metabolism -- Blood Flow, PET, Beam Neuropsychological Assessment |
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what is an impairment of ability to execute a skilled motor act even though now motor paralysis?
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apraxia
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_____ apraxia is when loss of ability to proper use of an object due to lack of perception of it's purpose
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sensory
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_____ is failure or inability to recognize the importance of sensory impressions.
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agnosia
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___________-agnosia is an inability to recognize the significance of sounds.
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auditory
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_____- agnosia is the when the words are seen but not recognized.
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visual
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________ is suppression of vision in one eye
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anopsia
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___-- absence of the sense of taste
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ageusia
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_________ absence of the sense of smell
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anosmia
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loss of the ability to write
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agraphia
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inability to remember the names of objects
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anomia
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visual aphasia or word blindness
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alexia
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failure in the formulation of speech event though comprehension of language is normal
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expressive aphasia
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inability to read music
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musical alexia
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impairment of ability to comprehend written language
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dyslexia
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disturbance or loss of ability to comprehend, elaborate, or express speech concepts
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aphasia
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what connects various lobes in the SAME hemispher together: cortical connections or:
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association fibers
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Name the association fibers of teh brain.
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Superior occipitofrontal
Superior longitudinal fasciculus Uncinate inferior occipitofrontal inferior longitudinal fasciculus |
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If you damage a fasciculus (association fiber) in the brain what is teh result?
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change in cognitive status
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What connects the front with the temporal lobe?
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uncinate
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What connects the temporal lobes
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anterior commissure
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What connects the frontal and parietal and occipital lobes (INTERHEMISPHERIC)
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corpus callosum
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What connects gyri?
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arcuate fibers
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What runs along the corpus callosum and connects the limbic lobes -
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cingulum
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How many neurons are in the cortex?
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20-23 Billion
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What are the parts of the corpus callossum?
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rostrom genu, body, splenium
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How many synpases are in the brain
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1.5 quadrillion
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What area is primary motor?
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4
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What area do you visualize
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39
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Where are the language areas
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40,39,19
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What B area do you find deja vue?
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20,21 Deja Vue
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What B area is Broca's area?
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Broca’s Area 44, 45(dominant hemisphere) - left
Motor Speech |
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3,1,2 Primary Sensory Lesion-
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sensory neglect of contralateral body.
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Lesion: 5,7
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lose quality of sensation
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What is area 22, and what happens if you lesion it?
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Weineke’s area- lesion hear words but
can’t speak word! |
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What area is 5,7 what if you lesion it?
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Sup Parietal
Primary association Get info from primary sensory and put Meaning to it (cold vs hot, rough vs smooth Lesion: Tactile Agnosia! |
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What is area 41, 42
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41,42 pri auditory Transverse gyrus of Heshel
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Lesion area 6:
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Apraxia
inability to accomplish a given movement! NO muscle weakness or impairment! |
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What is area 18,19 responsible for?
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19,18 Visual Association - Objects appear
lesion – physic blindness. Agnosia (visual) cannot recognize object but know it with other senses |
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What is non-fluent aphasia
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44,45 Broca’s non fluent aphasia: Understand but can’t speak
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What is area 17 responsible for?
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Primary visual lesion- cortical blindness
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What does the cingulate and entorhinal cortex do?
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Cortex- Cingulate- entorhinal-hippocampus
Learning and memory |
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What % or R handers have dominant R hemisphere?
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90-95% of right handed people
have dominant left hemisphere |
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Stereognosis:
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Figuring out the shape of an
object or direction and speed of the stimulus |
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Drawing, music, spatial perception
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R hemisphere
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Calculation and language
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is on L hemisphere
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T/F Most left-handed people also have
Dominant left hemisphere, but more Likely to have a dominant right Than right handed persons. |
true
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which hemisphere has speech and writing?
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Left
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What hemisphere is non-dominant and considered "artsy"
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R
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What artery runs along the ventral surface of the brainstem?
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basilar
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Stroke here
ACA = |
lower leg, foot contralateral
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Stroke here MCA =
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upper body contralateral
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he anterior cerebral arteries (ACA) are a pair of arteries on human anatomy that the supplies oxygen to most .
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medial portions of frontal lobes and superior medial parietal lobes
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The posterior cerebral artery (PCA) is one of a pair of blood vessels that supplies oxygenated blood to the .
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posterior aspect of the brain (occipital lobe) in human anatomy]
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The middle cerebral artery (MCA) is one of the three major paired arteries that supplies blood to the _________. The MCA arises from the internal carotid and continues into the lateral sulcus where it then branches and projects to many parts of the _____________. It also supplies blood to the anterior __________ and the insular cortices.
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cerebrum, lateral cerebral cortex,temporal lobes
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