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44 Cards in this Set

  • Front
  • Back

Stimulants increase chemical and electrical activity in which systems of the body

Central nervous system, somatic nervous system, peripheral nervous system
what happens when stimulants are used in large quantities or over a long period of time
The user depletes their energy supply and is left without reserves
The “crash” and subsequent withdrawal symptoms from strong stimulants results in
severe depression and lack of energy for days to months.
The reward/reinforcement pathway exists
in all mammals
The neurotransmitter most associated with the reward/reinforcement pathway is
dopamine
Cardiovascular side effects of stimulant drugs
Blood vessel constriction and spasms, weakened blood vessels and increased risk of stroke, increased heart rate and blood pressure
Initially, strong stimulants
increase confidence and induce euphoria
With prolonged use of strong stimulants this can occur
Psychosis and paranoia
Who was the author of Über Coca, a book that promoted the use of refined cocaine hydrochloride in the late 1800s
Sigmund Freud
In 1853, this discovery later allowed cocaine users to experience an intense rush and the highest blood levels of cocaine
The hypodermic needle
Because cocaine constricts blood vessels slowing the flow of blood, snorting cocaine is
a self-limiting method of use
Cocaine doesn’t stimulate a person for as long as amphetamines because it is
metabolized very quickly
What neurotransmitter reuptake ports are blocked by cocaine thus producing most of its effects
Norepinephrine and dopamine
Effects of Cocaine
Keeps endogenous DA and NE in the synaptic cleft longer, dilates the bronchi, causes a rapid rush that diminishes rapidly
Excessive dopamine from cocaine use over-stimulates the brain’s fright center to cause
Paranoia
Cocaine’s effects on sexual behavior
high dose chronic use results in sexual dysfunction, low dose use enhances sexual desire and delays ejaculation, disinhibiting effects lead to high-risk sexual behaviors
When cocaine and alcohol are used at the same time the byproduct of their metabolism is
cocaethylene
Physiologically, long-term cocaine use is most damaging to
heart and blood vessels
Many abnormalities in newborns of drug using mothers are caused by which of the following
the lifestyles of the drug using mother.
What best describes the condition of anhedonia
Inability to feel pleasure.
Cocaine paranoid psychosis is difficult to distinguish from schizophrenia because
both result from dopamine imbalances in the mesolimbic dopamine pathway.
Since cocaine is an intense stimulant, a common polydrug problem is its use
with downers to counter the side effects of each other.
Crack cocaine may be more addicting than powder cocaine because smoking it
delivers a higher dose in the system over a short period of time, in the freebase form allows it to be more readily absorbed by fat cells in the brain, delivers cocaine to the brain faster than even injecting powder cocaine.
Amphetamines can best be described by which of the following
Synthetic stimulants similar to cocaine but lasting longer and a bit cheaper to use.
Describe the brain action of amphetamines
they force the release of catecholamines from vesicles, they reverse direction of transporters to expel catecholamines into the synaptic gap, they block the enzymes that metabolize catecholamines
Other medical uses of amphetamines
epilepsy, narcolepsy, ADHD
Street name for smokable form of methamphetamine
Ice
Amphetamine psychosis is best characterized by
pressed speech and paranoia
This neurotransmitter is thought to be depleted in individuals with ADHD
Dopamine
Caffeine is an alkaloid of which class
Xanthines
The half-life of caffeine in a normal 25 year old adult is about
3-7 hours
What best describes nicotine withdrawal symptoms
irritability, headache and sleep problems
What percent of those who ever try a cigarette will become daily habitual smokers
25 percent
Energy drinks (Red Bull, Rock Star) contain more or less caffeine than Coca Cola
much greater amounts (80-160 mg)
True or False -Stimulants deplete the body’s energy chemicals when used chronically
True
True or False - Stimulants cause constriction of blood vessels, raising blood pressure
True
True or False - The strongest physical and mental dependence to stimulants develops from the use of tobacco
True
True or False - Cocaine is an illegal drug, it has no medical use today
False
True or False - Most soft drinks, including some orange and lemon-lime sodas contain caffeine
True
True or False - The most important reason people continue to smoke is to avoid withdrawal symptoms
True
True or False - Cancer, respiratory disease and cardiovascular diseases are the three most common medical problems associated with smoking tobacco
True
Many experts who treat patients with ADD/ADHD have found best treatment to be
psychotherapy and stimulants combination
Describe the phases of the reward/reinforcement circuit
activation of the nucleus accumbens septi to do the drug or behavior again and again, anticipation of the drug or behavior which causes craving for the stimulus, activation of the orbitofrontal cortex which affects the decision making process for continued use or behavior
Neurotransmitters are synthesized within the neuron and then stored in tiny sacs called
Vesicles