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57 Cards in this Set

  • Front
  • Back
Bacteria
prokaryotes, have no true nucleus, unicellual
Bacteria shapes
cocci (circle),
bacillus (oblong),
vibrio (fetal)
Mycobacteria
myco means waxy, thick waxy cell wall
ex: leprosy, TB
Mycobacterium leprae
Leprosy
Leprosy
slow growing, difficult to transmit
2 forms:
Tuberculoid (paucibacillary)
Lepromatous (multibacillary)
Tuberculoid (paucibacillary)
Leprosy: skin and nerves only, hypopigmented lesions, minor loss of sensation, may spontaneously heal
Lepromatous (multibacillary)
Leprosy: many skin lesions, nodules, skin, nerves, bones affected, is infectious
Leonine facies
Lion face, result of leprosy
Penciling
MP (metacarpal, phalangeal), deterioration of bone causing loss of digits; nerve damage allows for damage and infection of other bacterial attack
King Uzziah
King in bible, who is stuck by god and receives Leprosy: Leprosy results from sin, carnal desires, immorality
Leprosarium
place where lepers are sent to live separate from others
Kalaupapa
island of Hawaii, 1866 lepers shipped there
Father Damien
Belgian Catholic Priest 1873 cared for lepers at Kalaupapa Leprosarium, died 1889
Gerhard Hansen
norweigian doctor, 1873 identified bacillus (m. leprae) in patient, was first discovery of disease casing bacterium, idea was stolen by another
Hansen’s disease
– leprosy alt name honoring dr Hansen, no negative connotations
9-banded armadillo
only other animal affected by leprosy
Characteristics favoring eradication
humans are primary reservoir, cases rarely originate otherwise, if reduced enough, resurgence unlikely
Baccilus anthracis
rod-shaped, waxy shell; pigs, sheep, cows – lays in waste, decomposing body
Anthrax
can survive long period of time by spores, decades dormant (in soil or grass)
Cutaneous anthrax
spores enter wound on skin, most common but not fatal; kills skin tissue, blackened mass dead tissue, scar
Inhalational anthrax
– rare but fatal (flu-like symptoms), 1 wk or so short breath, close to 100% fatality
Gastrointestinal anthrax
– ingested, rarest form (in US), moderately fatal, symptoms: bloody diarrhea, adominel pain, vomiting
Woolsorter’s disease
industrial handling of animal byproduct, anthrax
Robert Koch
german physician who discovered anthrax, considered one of the founders of bacteriology
Sverdlovsk
– inhalation anthrax outbreak in Soviet Union affected at least 94 ppl, killed at least 64, covered up by government
2001 bioterror in the US
22 cases, 11 inhalation, 11 cutaneous, 7 states, 5 deaths; inside job, infectious strain (ames), milled, antistatic, lab worker suspected
Salmonella
10% fatality, headache, fever, abdominal pain, human disease, fecal/oral route, rare in US; prevalent in areas where health infrastructure is damaged
Hansen’s disease
– leprosy alt name honoring dr Hansen, no negative connotations
9-banded armadillo
only other animal affected by leprosy
Characteristics favoring eradication
humans are primary reservoir, cases rarely originate otherwise, if reduced enough, resurgence unlikely
Baccilus anthracis
rod-shaped, waxy shell; pigs, sheep, cows – lays in waste, decomposing body
Anthrax
can survive long period of time by spores, decades dormant (in soil or grass)
Cutaneous anthrax
spores enter wound on skin, most common but not fatal; kills skin tissue, blackened mass dead tissue, scar
Inhalational anthrax
– rare but fatal (flu-like symptoms), 1 wk or so short breath, close to 100% fatality
Gastrointestinal anthrax
– ingested, rarest form (in US), moderately fatal, symptoms: bloody diarrhea, adominel pain, vomiting
Woolsorter’s disease
industrial handling of animal byproduct, anthrax
Robert Koch
german physician who discovered anthrax, considered one of the founders of bacteriology
Sverdlovsk
– inhalation anthrax outbreak in Soviet Union affected at least 94 ppl, killed at least 64, covered up by government
2001 bioterror in the US
22 cases, 11 inhalation, 11 cutaneous, 7 states, 5 deaths; inside job, infectious strain (ames), milled, antistatic, lab worker suspected
Salmonella
10% fatality, headache, fever, abdominal pain, human disease, fecal/oral route, rare in US; prevalent in areas where health infrastructure is damaged
William Budd
1811-1880, English doctor, contra miasma theory, believed person to person, early contagionist-rural doctor
George Soper
hired to investigate Mary Mallon
Typhoid Mary
Irish cook in NYC, quarantined twice, caused families she worked for to come down with typhoid, was carrier: invaded biliary tract, excretes through feces, didn’t wash hands
Cholera
acute diarrheal disease usually accompanied by vomiting, produces extreme dehydration with high rate of mortality
Vibrio cholerae
bacillus shaped like a coma with flagellum, seen in excreta and intestinal contents of cholera victims
Filippo Pacini
saw cholera in excreta and intestinal contents of cholera victims and documented it 1854, in Florence; still holds name Vibrio by Pacini, did not make big impact then
Robert Koch
during 5th pandemic 1881-1896 conducted research in Calcutta and Alexandria led to identification and isolation of causative bacterium
Plague
14th century plague evolved from pneumonic to bubonic within changing seasons
Yersinia pestis
bacillus lives in bloodstream of animal or stomach of flea, how plague is spread
Bubonic plague
disease attacking lymph nodes, bubos develop on groin, armpit, neck, subcutaneous hemorrhaging, poisons nervous system
Septicemic plague
transmitted by insects, blood is infected w/ bacillus, victim dead before buboes form, rarest of 3 interwoven diseases that make up black death, as lethal as pneumonic
Plague pneumonia
– 2nd form, attacked lungs, nearly 100% fatality, killed more quickly, most infectious of trio
Buboes
size of almond, sometimes an orange, found in groin, armpit, neck
Black death
consists of 3 plague/disease, 14th century killed 1/3 of Europe population, evolved from pneumonic to bubonic within changing seasons
Epizootic
– disease that spread among animals and humans
Brotherhood of the Flagellants
religious brotherhood taken to beating themselves bloody with whips to atone for sins
Influenza
RNA virus, single-stranded, 8 strands; was first thought to be caused by mal aligned stars/planets, astronomy