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5 Cards in this Set

  • Front
  • Back
terbinafine
synthetic allylamine with structure and activity related to naftifine
axn
inhibits squalene monooxygenase -> interuption of fungal sterol biosynthesis
activity
dermatophytic fungi
(trichophyton microsporum and epidermophyton)
filamentous fundi (aspergillus)
dimorphic fingi (blastomycoses)
yeasts
oral terbinafine use
infxn of toenail and fingernail (onychomycosis, tinea unguium)
tinea capitis and corporis infxn
adv eff
tasete or ocular disturbances
sympthomatic hepatobiliary dysfxn
dec in lymphocyte count and neutropenia and serious skin infxn