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20 Cards in this Set
- Front
- Back
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ARBs/ACE inhibitors |
Renal damage - oligohydramnios |
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Alkylating agents |
Absence of digits, multiple anomalies |
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Aminoglycosides |
Ototoxicity |
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Antiepileptic drugs - Carbamazepine, phenytoin, phenobarbital |
Neural tube defects, cardiac defects, cleft palate, skeletal abnormalities (e.g. phalanx/nail hypoplasia, facial dysmorphism) |
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Diethylstilbestrol |
Vaginal clear cell carcinoma, congenital Mullerian anomalies |
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Folate antagonists - Trimethoprim, methotrexate, antiepileptics |
Neural tube defects |
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Isotretinoin |
Multiple severe birth defects |
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Lithium |
Epstein anomaly (atypical displacement of tricuspid valve) |
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Methimazole |
Aplasia cutis congenita |
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Tetracyclines |
Discolored teeth, inhibited bone growth |
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Thalidomide |
Limb defects (phocomelia, micromelia - "flipper" limbs) |
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Warfarin |
Bone deformities, fetal hemorrhage, abortion, ophthalmologic abnormalities |
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Alcohol |
Common cause of birth defects and intellectual disability; fetal alcohol syndrome |
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Cocaine |
Low birth weight, preterm birth, IUGR, placental abruption |
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Smoking (nicotine, CO) |
Low birth weight (leading cause in developed countries), preterm labor, placental problems, IUGR, SIDS |
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Iodine (lack or excess) |
Congenital goiter or hypothyroidism (cretinism) |
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Maternal diabetes |
Caudal regression syndrome (anal atresia to sirenomelia), congenital heart defects, neural tube defects, macrosomia |
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Methylmercury - highest in swordfish, shark, tilefish, king mackerel |
Neurotoxicity |
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Vitamin A excess |
Extremely high risk for spontaneous abortions and birth defects (cleft palate, cardiac) |
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X-rays |
Microcephaly, intellectual disability |
