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26 Cards in this Set
- Front
- Back
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ACE inhibitors |
renal damage |
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alkylating agents |
absence of digits |
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aminoglycosides |
CN VIII toxicity |
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CBZ |
facial dysmorphism developmental delay NTDs phalanx/fingernail hypoplasia |
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Phenytoin |
fetal hydantion syndrome: cleft palate cardiac defects phalanx/fingernail hypoplasia microcephaly |
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DES |
vaginal clear cell adenocarcinoma Mullerian abnormalities (vaginal atresia, bifid uterus, etc) |
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folate antagonists (TMP, pyrimethamine, MTX) |
NTDs |
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Isoretinoin |
contraception mandatory severe birth defects |
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methimazole |
aplasia cutis congenita (scalp) also seen in Patua |
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tetracyclines |
discolored teeth |
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thalidomide |
limb defects |
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valproate |
inhibited maternal folate absorption causes NTDs |
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warfarin |
bone deformities fetal hemorrhage abortion eye abnormalities |
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alcohol |
MR facial abnormalities (hypertelorism, smooth philtrum) limb dislocation heart lung fistulas holoprosencephaly microcephaly **cell migration failure** |
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cocaine |
IUGR placental abruption prematurity |
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smoking (nicotine, CO) |
LBW and IUGR preterm labor placenta issues ADHD |
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maternal diabetes |
macrosomia hypoglycemia (baby makes too much insulin) caudal regression syndrome (anal atresia and sirenomelia) VSDs and transposition of BVs anencephaly |
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vitamin A excess |
spontaneous abortion cleft palate (craniofacial) posterior fossa abnormalities (dandy-walker, chiari malformation) great vessel abnormalities (ToF, etc) |
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x-rays |
microcephaly MR |
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Caudal regression syndrome |
maternal diabetes babies agenesis of sacrum and/or lumbar spine causes flaccid paralysis of LLs and absent reflexes at ankles contractures of feet anal atresia sirenomelia |
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dizygotic twins |
dichorionic diamniotic |
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monozygotic twins from 0-4 days |
25% dichorionic diamniotic split before morula |
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monozygotic twins that split between 4-8 days (before blastocyst) |
monochorionic diamniotic (same placenta but separate sacs) |
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monozygotic twins that split once blastocyst implants (8-12 days) |
monochorionic monoamniotic |
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monozygotic twins that split after 13 days once implanted |
conjoined (embryonic bilaminar disc already formed) |
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2 vessel cord |
single umbilical a Edwards syndrome |
