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35 Cards in this Set

  • Front
  • Back
facial dysmorphism, heart defects, growth retardation, ADD/ADHD
alcohol
IUGR, low BW, pre-term delivery, CL and P
cigarettes, marijuana
vascular disruptions assoc w/ cranium/limbs/genitals/etc, SAB's, placental/uterine rupture
cocaine
stippled epiphyses, nasal hypoplasia, MR, seizures
warfarin embryopathy/fetal coumadin syndrome
transposition of great vessels, ASD, VSD, tet of fallot, GI/GU issues, caudal regression, NTD's, microcephaly, CL+/-P
diabetes
microtia, anotia, thymic anomalies, cardiovascular defects, CNS defects, DD
accutane
increased birth defects and SAB's, hypoxia, acidosis, preeclampsia, premature labor
epilepsy
phocomelia, amelia, clubfoot, supernumerary fingers, VSD, ASD, conotruncal, microtia, clefts
thalidomide
Dandy-Walker, polycystic kidneys, CP, microcephaly, dysmorphism, MR, low BW, small head circumference
Benzodiazepenes
nail hypoplasia, cardiac defects, DD, 1% NTD risk, short nose with broad philtrum
Tegretol
MR, similar to facial characteristics of FAS, heart defects
maternal PKU
CL+/-P, hypoplasia, cardiac defects
phenylhydantoin
CL+/- CP, long fingers and toes, 1-2% risk NTD
valproic acid
petechiae, blindness, deafness, epilepsy, CP, MR
CMV
deafness*, MR, long bone ossification, cardiac issues, hepatosplenomegaly, MR, ocular defects
Rubella
increased risk of vaginal adenocarcinoma, genital anomalies
DES
brachycephaly, CP, craniosynostosis
fluconazole
ebstein's anomaly of tricuspid valve
lithium
aplasia cutis congenita of scalp
methiamazole
limb reduction defects, moebius syndrome, cns anomalies, arthrogyposis
Misopristol
cutis laxia
penicillamine
limb reduction defects, skin scarring, microcephaly, chorioretinitis, neurologic abnormalities, IUGR
varicella zoster
hydrocephalus, microcephaly, microopthalmia, chorioretinitis, intracranial calcs, seizures, blindness, deafness, MR, prematurity, SB
toxoplasmosis
severe anemia, hydrops, IUFD, IUGR
parvo/5th dz
microcephaly, CP, MR, ataxia, psychomotor retardation
methylmercury
microcephaly, growth retardation, MR, mutagenesis, carcinogenesis
XRT
hearing loss, damage to 8th nerve
streptomycin
teeth yellow, caries, enamel hypoplasia
tetracycline
ONTD's, growth deficiency, CNS defects
hyperthermia
small increased risk of IQ decrease
lead
similar facial issues as FAS, microcephaly, CNS dysfunction, growth deficiency
toluene
lack of calvarial ossification, growth deficiency, mild MR
chemo (aminopterin, methotrexate)
IUGR, hypocalvaria, persistent patent ductus, renal tubular dysplasia, Potter's syndrome
ACE inhibitors
grwoth deficiency, mental deficiency, cardiac septal defects, poorly developed ear helices and craniofacial anomalies
trimethadione
masculinization of females and labial fusion
steroids