Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
35 Cards in this Set
- Front
- Back
facial dysmorphism, heart defects, growth retardation, ADD/ADHD
|
alcohol
|
|
IUGR, low BW, pre-term delivery, CL and P
|
cigarettes, marijuana
|
|
vascular disruptions assoc w/ cranium/limbs/genitals/etc, SAB's, placental/uterine rupture
|
cocaine
|
|
stippled epiphyses, nasal hypoplasia, MR, seizures
|
warfarin embryopathy/fetal coumadin syndrome
|
|
transposition of great vessels, ASD, VSD, tet of fallot, GI/GU issues, caudal regression, NTD's, microcephaly, CL+/-P
|
diabetes
|
|
microtia, anotia, thymic anomalies, cardiovascular defects, CNS defects, DD
|
accutane
|
|
increased birth defects and SAB's, hypoxia, acidosis, preeclampsia, premature labor
|
epilepsy
|
|
phocomelia, amelia, clubfoot, supernumerary fingers, VSD, ASD, conotruncal, microtia, clefts
|
thalidomide
|
|
Dandy-Walker, polycystic kidneys, CP, microcephaly, dysmorphism, MR, low BW, small head circumference
|
Benzodiazepenes
|
|
nail hypoplasia, cardiac defects, DD, 1% NTD risk, short nose with broad philtrum
|
Tegretol
|
|
MR, similar to facial characteristics of FAS, heart defects
|
maternal PKU
|
|
CL+/-P, hypoplasia, cardiac defects
|
phenylhydantoin
|
|
CL+/- CP, long fingers and toes, 1-2% risk NTD
|
valproic acid
|
|
petechiae, blindness, deafness, epilepsy, CP, MR
|
CMV
|
|
deafness*, MR, long bone ossification, cardiac issues, hepatosplenomegaly, MR, ocular defects
|
Rubella
|
|
increased risk of vaginal adenocarcinoma, genital anomalies
|
DES
|
|
brachycephaly, CP, craniosynostosis
|
fluconazole
|
|
ebstein's anomaly of tricuspid valve
|
lithium
|
|
aplasia cutis congenita of scalp
|
methiamazole
|
|
limb reduction defects, moebius syndrome, cns anomalies, arthrogyposis
|
Misopristol
|
|
cutis laxia
|
penicillamine
|
|
limb reduction defects, skin scarring, microcephaly, chorioretinitis, neurologic abnormalities, IUGR
|
varicella zoster
|
|
hydrocephalus, microcephaly, microopthalmia, chorioretinitis, intracranial calcs, seizures, blindness, deafness, MR, prematurity, SB
|
toxoplasmosis
|
|
severe anemia, hydrops, IUFD, IUGR
|
parvo/5th dz
|
|
microcephaly, CP, MR, ataxia, psychomotor retardation
|
methylmercury
|
|
microcephaly, growth retardation, MR, mutagenesis, carcinogenesis
|
XRT
|
|
hearing loss, damage to 8th nerve
|
streptomycin
|
|
teeth yellow, caries, enamel hypoplasia
|
tetracycline
|
|
ONTD's, growth deficiency, CNS defects
|
hyperthermia
|
|
small increased risk of IQ decrease
|
lead
|
|
similar facial issues as FAS, microcephaly, CNS dysfunction, growth deficiency
|
toluene
|
|
lack of calvarial ossification, growth deficiency, mild MR
|
chemo (aminopterin, methotrexate)
|
|
IUGR, hypocalvaria, persistent patent ductus, renal tubular dysplasia, Potter's syndrome
|
ACE inhibitors
|
|
grwoth deficiency, mental deficiency, cardiac septal defects, poorly developed ear helices and craniofacial anomalies
|
trimethadione
|
|
masculinization of females and labial fusion
|
steroids
|