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20 Cards in this Set
- Front
- Back
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ACEIs
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Renal damage
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Alkylating agents
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Absence of digits, multiple anomalies
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Aminoglycosides
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CN VIII toxicity
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Carbamazepine
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NT defects, carniofacial defects, finger hypoplasia, dev delay, IUGR
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Diethylstilbestrol (DES)
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vaginal clear cell adenocarcinoma
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Folate Antagonists
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NT defects
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Lithium
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Ebstein's anomaly (atrialized RV)
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Phenytoin
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Fetal hydantoin syndrome: microcephaly, dysmorphic carniofacial features, hypoplastic nails and distal phalanges, cardiac defects, IUGR, mental retardation
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Tetracyclines
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Discolored teeth
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Thalidomide
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Limb defects (fipper limbs) - phocomelia
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Valproate
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Inhibition of maternal folate absopriton > NT defects
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Warfarin
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Bone deformities, fetal hemorrhage, abortion, opthalmogic abnormalities
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Alcohol
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FAS - leading cuase of birth defects and mental retardation
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Cocaine
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Abnormal fetal development and fetal addiction; placental abruption
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Smoking (nicotine, CO)
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Preterm labor, placental problems, IUGR, ADHD
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Iodide (lack or xs)
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Congenital goiter or hypothyroidism (hypo -> cretinism)
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Maternal Diabetes
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Caudal regression syndrome (anal atresia to sirenomelia), congenital heart defects, NT defects
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Vitamin A (xs)
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Extremelyhigh risk spontaneous abortions and birht defects (cleft palate, cardiac abnormalities)
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X-rays
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Microcephaly, Mental retardation
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Uncontrolled HTN
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Uteroplacental insufficiency -> fetal death/IUGR, increased risk of placental abruption not a/w congential defects
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