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32 Cards in this Set

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agonist
produce effects similar to those produced by a neurotransmitter
partial agonist
produce effects similar to but less than that produced by aneurotransmitter
inverse agonist
produce effects oppositve those produced by a neurotransmitter
antagonist
bloack effects of nt
traditional (conventional) antipsychotics
considered more effective for positive sx of schizophrenia
block dopamine receptors (antagonists)
side effects of traditional antipsychotics
anticholinergic effect
extrapyramidal effects
neuroleptic malignant syndrome (NMS)(muscle rigidity tachycardia, fever, alterred states of consciousness requires immediate d/c of NMS
examples of traditional antipsychotics
chlorpromazine (thorazine)
thiroidazine (Mellaril)
halperidol (Haldol)
chlorpromazine
thorazine
thiroidazine
mellaril
haloperidol
haldol
atypical antipsychotics
help with negative symptoms examples include clozapine (clozaril), risperidone (Risperdal) Olexapine
(Seroquel)
acts on dopamine, 5ht, and NE
pros and cons of atypicals
less tardive dyskinesia
granolcytosis
anticholingergic effects
obesity diabetes
Tricyclics (TCAs)
examples
imipramine (Tofranil)
doxepin (Sinequan)
clomipramine (Anafranil)
TCA's uses
typical depression
OCD
panic disorder
enureses
TCA mode of action
block reuptake of Norepinephrine, serotonin and dopamine
TCAs side effects
overdoese
anticholingergic symptoms
GI problems
confusion memory problems
cardiotoxic and lethal
SSRIs mode of action
blocks reuptake of serotonin
SSRI side effects
insomnia, anorexia, sexual dysfunction, GI disturbance, less likely to cause cognitive problems and anticholinergic effects
MAO-I's examples
phenilzine (Nardil)
tranylcypromine (Parnate)
Uses for MAO-I's
atypical depression
mode of action for MAO-I
inhibits monoamine oxidase which deactivates dopamine norepinephrine and serotonin
side effects of MAO-i
hypertensive crisis (severe HA elevated BP, convulsions)
anticholinergic, isomnia, foods containing tyramine
mood stabilizers examples
carbamazepine (Tegretol)
valproic acide (Depakote)
lithium (drug of choice for bipolar DO)
mode of action for mood stabilizers
affect reuptake of serotonin and norepinephrine
side effects mood stabilizers
lithium-nausea, polydipsia, polyuria , cognitive dist.
cabamazepine- lethargy, termor, ataxia, visual disturbance
anxiolytics (benzodiazepines)
alprazolam (Xanax)
chlordiazepoxide (Librium)
diazepam (Valium)
anxiolytics mode of action
increase GABA levels
anxiolytics side effects
drowsiness and sedation, confusion and disorientation, paradoxical excitation, highly addictive,
Beta blockers uses
propranolol (Inderal)
used for HTN, angina, migraines, essential tremor, anxiety
psychostimulants
methylphenidate (Ritalin)
pemoline (Cylert)
Adderoll
mode of action for beta blockers
block receptors that resopnd to epinephrine and norepinephrine
side effects of psychostimulants
dysphoria, tic disroder, decreased appetites, OCD symptoms,