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22 Cards in this Set
- Front
- Back
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avg 1/2 life of erythrocytes = ?
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120 days
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name the 6 stages of erythropoiesis
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pronormoblast, basophilic normoblast, polychromatic normoblast, orthochromatic normoblast, reticulocyte, mature RBC
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T/F: reticulocyte contains some rRNA
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T, even though it has extruded its nucleus, it still contains some rRNA and is thus still capable of making Hb
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as erythropoiesis occurs, there is a _(inc/dec)_ in RNA and and _(inc/dec)_ in Hb
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dec in RNA, inc. in Hb as RBCs mature
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the _______ erythroblast is the last immature RBC to divide
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polychromatic
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reticulocytes stain with a _______ stain that stains the RNA
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supravital
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quality ______A________ is the periodic monitoring of precsion and accuracy of equipment, technique, and testing; federal law requires quality _____A______ accreditation, proficiency testing, and inspections
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control (bare-minimum quality req'd)
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quality ______A________ is the integrated process by which the desired and feasible level of quality is affected; there is a quality _______A________ section, department, and/or institution.
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improvement (QI + some)
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what does HTC stand for? What is it also know as (3-letter abb)?
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hematocrit; PCV - packed cell volume; it's expressed as the % of cell mass relative to the total vol of whole blood in the sample; automated machine measure MCV and calculate HCT
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what does MCV stand for?
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mean corpuscular volume- it represents the avg volume of a RBC and gives an avg RBC size
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what does MCH stand for?
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mean cell Hb - represents the content of Hb in the avg RBC
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what does MCHC stanf for?
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mean cell Hb concentration - measures the conc of HB in the avg RBC
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what does RDW stand for?
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Red cell distribution width - it’s a coefficient of variation (st dev) fro the distributino of RBC; a measure of anisocytosis (variation of RBC size)
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what does MPV stand for?
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Mean platelet volume - avg platelet size; thus, a high MPV = high variation in size
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what manual counts still occur today (as opposed to automated counts)
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WBCs and RBCs for fluids (spinal, peritoneal, etc)
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2 methods for cell counts (automated): 1) _______ method - sp'c amt of diluted blood flows through a small aperature btw 2 sensing electrodes, amp of pulse produced is proportional to cell volume; 2) _____ method - a sp'c amt of dilute blood is hydrodynamically focused in a flow cell illuminated by a beam of light --> light scatters --> pulse, amp is proportional to cell volume
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1) impedence method, 2) light scattering method
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HTC x 10 =
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RBC count
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(MCV x RBC)/10 = ?
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HTC
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(HGB x 10)/RBC count = ?
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MCH - calc represents the content of Hb in the avg RBC
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(HGB x 100)/HTC % = ?
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MCHC - measures the conc of HB in the avg RBC
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corrected retic = (retic x HTC of pt)/45[avg HTC] reticulocyte count is corrected b/c …. ?
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it is corrected to the degree of anemia in each pt to better estimate the adequacy of the bm response
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reticulocytes are ______chromatophilic
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polychromatophilc and stain with SUPRAVITAL methylene blue stain
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