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25 Cards in this Set

  • Front
  • Back
spasticitiy is a ___ dysfunc
CNS
tension developed in athlete in muscle spasm is involuntary and athlete is ___
unable to completely relax the muscle
centrally acting GABA-B agonist
Baclofen
GABA-A agonist used for spasticity which causes sedation
diazepam
X2 centrally acting muscle relaxant c less side effects than clonidine
tizanidine
x2 centrally acting agent which activates inh neuron which reduces symp outflow which decrease vasomotor tone and HR
clonidine
drugs that create a sedative effect which allows the athlete to relax and rest allowing muscle to repair itself
centrally acting drugs
these two drugs are usually combined c muscle relaxants to produce an analgesic effect
ASA or Acetaminophen
instance where baclofen is contraindicated
peptic ulceration
instance where dantrolene is contraindicated
hepatic impairment, pregnancy, acute muscle spasm and breat feeding
acts directly on skeletal muscle and produces fewer central adverse effects
dantrolene
inh transmission at spinal level and depresses CNS
Baclofen
indicated for spasticity assoc c MS or SC injury or dx
Tizanidine
other uses for tizanidine
trigeminal neuralgia, chronic LBP, cluster HA, chronic HA, Chronic tension type HA
muscle relaxants used for chronic LBP
centrally acting, structural similar to tricyclics and nocturnal muscle spasms
Cyclobenzaprine
precursor of meprobamate, reduction of muscle spasms and bad withdrawal symptoms
Carisoprodol
investigative usage for MS and used clinically for reduction of muscle spasms
Methocarbamol
Has side effects of Nausea, drowsiness, and dizziness
Metaxalone
Analog of diphenhydramine, given iv for antispasticity trials and its side effects is rare aplastic anemia
Orphenadrine Citrate
2 drugs that commonly cause DUIs
Carisoprodol/Meprobamate
Muscle relaxants
Inapropriate use
anticholinergic side effects, sedation, weakness
approprita use
less than 7 days for acute indication
alternatuves to muscle relaxants
baclofen and tizanidine