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25 Cards in this Set
- Front
- Back
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spasticitiy is a ___ dysfunc
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CNS
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tension developed in athlete in muscle spasm is involuntary and athlete is ___
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unable to completely relax the muscle
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centrally acting GABA-B agonist
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Baclofen
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GABA-A agonist used for spasticity which causes sedation
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diazepam
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X2 centrally acting muscle relaxant c less side effects than clonidine
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tizanidine
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x2 centrally acting agent which activates inh neuron which reduces symp outflow which decrease vasomotor tone and HR
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clonidine
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drugs that create a sedative effect which allows the athlete to relax and rest allowing muscle to repair itself
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centrally acting drugs
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these two drugs are usually combined c muscle relaxants to produce an analgesic effect
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ASA or Acetaminophen
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instance where baclofen is contraindicated
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peptic ulceration
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instance where dantrolene is contraindicated
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hepatic impairment, pregnancy, acute muscle spasm and breat feeding
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acts directly on skeletal muscle and produces fewer central adverse effects
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dantrolene
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inh transmission at spinal level and depresses CNS
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Baclofen
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indicated for spasticity assoc c MS or SC injury or dx
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Tizanidine
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other uses for tizanidine
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trigeminal neuralgia, chronic LBP, cluster HA, chronic HA, Chronic tension type HA
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muscle relaxants used for chronic LBP
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centrally acting, structural similar to tricyclics and nocturnal muscle spasms
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Cyclobenzaprine
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precursor of meprobamate, reduction of muscle spasms and bad withdrawal symptoms
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Carisoprodol
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investigative usage for MS and used clinically for reduction of muscle spasms
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Methocarbamol
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Has side effects of Nausea, drowsiness, and dizziness
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Metaxalone
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Analog of diphenhydramine, given iv for antispasticity trials and its side effects is rare aplastic anemia
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Orphenadrine Citrate
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2 drugs that commonly cause DUIs
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Carisoprodol/Meprobamate
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Muscle relaxants
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Inapropriate use
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anticholinergic side effects, sedation, weakness
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approprita use
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less than 7 days for acute indication
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alternatuves to muscle relaxants
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baclofen and tizanidine
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