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28 Cards in this Set
- Front
- Back
- 3rd side (hint)
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epinephrine
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alpha1>alpha2>beta1>beta2
low dose is selective for beta 1 |
anaphylaxis, glaucoma, asthma, hypotension
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NE
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alpha1&2>beta 1
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hypotension
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isoproterenol
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beta selectivity
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AV block
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dopamine
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d1&2>bet>alpha; inotropic and chronotropic
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shock and heart failure
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dobutamine
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beta1>beta2; only inotropic
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heart failure, cardiac stress testing
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phenylephrine
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alpha1>alpha2
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pupillary dilation, vasoconstriction, nasal decongestant
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metaproterenol
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selective beta2 agonist
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acute asthma
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albuterol
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selective beta2 agonist
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acute asthma
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salmeterol
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selective beta2 agonist
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long term treatment for asthma
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tertbutaline
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selective beta2 agonist
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reduce premature contractions
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amphetamine
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indirect general agonist, releases stored catecholamines
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narcolepsy, obesity, ADD
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ephedrine
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indirect general agonist, releases stored catecholamines
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nasal decongestion, urinary incontinence, hypotension
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cocaine
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indirect general agonist, uptake inhibitor
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causes vasoconstriction and local anesthesia
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clonidine
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centrally acting alpha 2 agonist, decreases central adrenergic outflow
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hypertension, especially with renal dz (does not decrease blood flow to kidneys)
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alpha-methyldopa
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centrally acting alpha 2 agonist, decreases central adrenergic outflow
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hypertension, especially with renal dz (does not decrease blood flow to kidneys)
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Phenoxybenzamine
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irreversible alpha blocker
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Use: Pheochromocytoma before surgery
Toxicity: orthostatic hypotension, reflex tachycardia |
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phentolamine
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reversible alpha blocker
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Use: Pheochromocytoma before surgery
Toxicity: orthostatic hypotension, reflex tachycardia |
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prazosin, terazosin, doxazosin
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selective alpha 1 blocker
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Use: hypertension, urinary retention in BPH
Toxicity: 1st dose orthostatic hypotension, dizziness, H/A |
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mirtazapine
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selective alpha 2 blocker
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Use: depression
Toxicity: sedation, increase serum cholesterol, increase appetite |
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acebutolol
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beta 1 selective blocker, partial agonist
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Use:
HTN: decrease CO and renin secretion Angina: decrease HR and contractility MI: decrease mortality CHF: slow progession Toxicity: Impotence, exacerbation of asthma, bradycardia, AV block, CHF; sedation, sleep alterations; use cautiously with diabetics |
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betaxolol
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beta 1 selective blocker
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Use:
HTN: decrease CO and renin secretion Angina: decrease HR and contractility MI: decrease mortality CHF: slow progession Toxicity: Impotence, exacerbation of asthma, bradycardia, AV block, CHF; sedation, sleep alterations; use cautiously with diabetics |
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esmolol
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beta 1 selective blocker, short acting
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Use:
HTN: decrease CO and renin secretion Angina: decrease HR and contractility MI: decrease mortality CHF: slow progession SVT: decrease AV conduction velocity (class II) Toxicity: Impotence, exacerbation of asthma, bradycardia, AV block, CHF; sedation, sleep alterations; use cautiously with diabetics |
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metoprolol
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beta 1 selective blocker
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Use:
HTN: decrease CO and renin secretion Angina: decrease HR and contractility MI: decrease mortality CHF: slow progession Toxicity: Impotence, exacerbation of asthma, bradycardia, AV block, CHF; sedation, sleep alterations; use cautiously with diabetics |
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propanolol
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non-selective beta blocker
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Use:
HTN: decrease CO and renin secretion Angina: decrease HR and contractility MI: decrease mortality CHF: slow progession SVT: decrease AV conduction velocity (class II) Toxicity: Impotence, exacerbation of asthma, bradycardia, AV block, CHF; sedation, sleep alterations; use cautiously with diabetics |
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timolol
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non-selective beta blocker
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Use:
HTN: decrease CO and renin secretion Angina: decrease HR and contractility MI: decrease mortality CHF: slow progession Glaucoma: decrease production of aqueous humor Toxicity: Impotence, exacerbation of asthma, bradycardia, AV block, CHF; sedation, sleep alterations; use cautiously with diabetics |
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pindolol
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non-selective beta blocker, partial agonist
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Use:
HTN: decrease CO and renin secretion Angina: decrease HR and contractility MI: decrease mortality CHF: slow progession Toxicity: Impotence, exacerbation of asthma, bradycardia, AV block, CHF; sedation, sleep alterations; use cautiously with diabetics |
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labetalol
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non-selective beta and alpha blocker
(carvedilol) |
Use:
HTN: decrease CO and renin secretion Angina: decrease HR and contractility MI: decrease mortality CHF: slow progession Toxicity: Impotence, exacerbation of asthma, bradycardia, AV block, CHF; sedation, sleep alterations; use cautiously with diabetics |
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atenolol
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selective beta 1 blocker
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Use:
HTN: decrease CO and renin secretion Angina: decrease HR and contractility MI: decrease mortality CHF: slow progession Toxicity: Impotence, exacerbation of asthma, bradycardia, AV block, CHF; sedation, sleep alterations; use cautiously with diabetics |
