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23 Cards in this Set

  • Front
  • Back
1. Known risk factors for squamous cell esophageal cancer?
a. Caustic burns
b. Alcohol consumption
c. Smoking
d. Nitrites and nitrates containing food
2. Risk factors for esophageal adenocarcinoma?
a. GERD
3. What Should think of in a patient who describes dysphagia to solid foods that developed over a fairly short period of time and with a hx of self-medicating w/PPIs.?
a. He may have had a history of GERD and has now developed adenocarcinoma of the distal esophagus.
4. If the patient were to describe a more protracted course (months to years) of dysphagia what would the differential diagnosis include?
1. Benign strictures
2. Congenital malformations
3. Achalasia
5. What is the most accurate imaging modality for identifying the depth of esophageal tumor invasion and for identifying regional nodal disease?
a. Endoscopic ultrasonography (EUS)
6. Endoscopic ultrasonography (EUS)?
a. Patients in whom lymphadenopathy is visualized, EUS – directed fine needle aspiration of the nodes can help confirm regional nodal mets.
7. Type I tumours w/Siewert classification of GE junction adenocarcinomas (Type I-III)?
a. Type one tumors are located more than 1 cm above the GE junction
b. Surgical treatment would generally consist of esophagectomy.
8. Type II tumours w/Siewert classification of GE junction adenocarcinomas (Type I-III)?
a. Located within 1 cm proximal and 2 cm distal to the GE junction.
b. Surgical treatment would consist of esophagectomy with partial resection of the proximal stomach.
9. Type III tumours w/Siewert classification of GE junction adenocarcinomas (Type I-III)?
a. Located more than 2 cm distal to the GE junction
b. Surgical treatment would consist of total gastrectomy
10. Transthoracic esophagectomy (TTE)?
a. This resection is traditionally done through an incision in the abdomen (or laparoscopic approach) and a separate incision through the right chest.
b. The stomach is brought into mediastinum and anastomosed to the proximal esophagus.
c. It is associated with a high rate of pulmonary complications due to pain from incisions in both the chest and upper abdomen.
11. Transhiatal esophagectomy?
a. This resection is done through an abdominal incision (or laparoscopic) and a cervical incision.
b. The gastric conduit is brought up through the posterior mediastinum and anastomosed to the cervical esophagus in the neck.
c. The major advantages of this approach a reduction in pulmonary complications compared to TTE and reduce mortality and morbidity associated with cervical anastomotic leaks.
12. Most predominant esophageal tumor type in the US?
a. Adenocarcinoma
13. Advantages of endoscopic stent placement for esophageal carcinoma?
a. Rapid relief of dysphagia
b. Treatment of choice for tracheoesophageal fistula
c. short procedural time/outpatient procedure
14. Disadvantages of endoscopic stent placement for esophageal cancer?
a. Recurrence due to stent migration
b. Tumor overgrowth
c. Food impaction
d. Transient pain following placement
e. Gastroesophageal reflux
f. Increased risk of late hemorrhage
15. Advantages of photodynamic therapy and laser for esophageal carcinoma-Endoluminal destruction of obstructing lesions for esophageal cancer?
a. Works well with exophytic lesions
b. Generally low complication rates
16. Disadvantages of photodynamic therapy and laser for esophageal carcinoma-Endoluminal destruction of obstructing lesions for esophageal cancer?
a. Often available only in specialized centres
b. Repeat treatment every 4 to 8 weeks is needed.
17. Advantages of single-dose brachytherapy-intraluminal radiotherapy for esophageal cancer?
a. Long-term dysphagia improvement is better than stent placement.
b. Long-term quality-of-life score was better compared with stent placement
c. Lower rate of hemorrhage and stent placement
18. Disadvantages of single-dose brachytherapy-intraluminal radiotherapy for esophageal cancer?
a. Dysphagia relief is delayed in comparison to stent placement.
19. Optimal palliative chemotherapy combination for esophageal cancer?
a. epirubicin, cisplatin, and 5-FU
20. Advantages of palliative chemotherapy for esophageal cancer (epirubicin, cisplatin, and 5-FU)?
a. Treatment improves median survival
b. Responders may have improved quality of life due to release of obstruction.
21. Disadvantages of palliative chemotherapy for esophageal cancer (epirubicin, cisplatin, and 5-FU)?
a. Response to obstruction is variable
b. Therefore, additional treatment for obstruction may be needed
c. Relief from obstruction may be delayed
22. In whom is esophagectomy primarily performed?
a. Patients with potentially curable esophageal cancers.
23. Complete
23. Complete